Timing matters: early administration of a high-affinity antibody targeting the tau repeat domain prevents aggregation in a mouse tauopathy model
时机至关重要:在小鼠tau蛋白病模型中,早期注射靶向tau重复结构域的高亲和力抗体可预防聚集。
期刊:Alzheimers Research & Therapy
影响因子:7.6
doi:10.1186/s13195-026-01985-x
Penny, Lewis K; Arastoo, Mohammad; Lofthouse, Richard; Abdallah, Aya; Imoesi, Peter I; Schwab, Karima; Shiells, Helen; Melis, Valeria; Riedel, Gernot; Harrington, Charles R; Wischik, Claude M; Porter, Andrew; Palliyil, Soumya