日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

An injectable PEG-like conjugate forms a subcutaneous depot and enables sustained delivery of a peptide drug

可注射的 PEG 类缀合物形成皮下储库,并能够持续输送肽类药物

Imran Ozer, Anna Slezak, Parul Sirohi, Xinghai Li, Nikita Zakharov, Yunxin Yao, Jeffrey I Everitt, Ivan Spasojevic, Stephen L Craig, Joel H Collier, Jonathan E Campbell, David A D'Alessio, Ashutosh Chilkoti

Polyethylene Glycol-Like Brush Polymer Conjugate of a Protein Drug Does Not Induce an Antipolymer Immune Response and Has Enhanced Pharmacokinetics than Its Polyethylene Glycol Counterpart

蛋白质药物的聚乙二醇类刷状聚合物结合物不会诱发抗聚合物免疫反应,且比聚乙二醇对应物具有增强的药代动力学

Imran Ozer, Garrett Kelly, Renpeng Gu, Xinghai Li, Nikita Zakharov, Parul Sirohi, Smita K Nair, Joel H Collier, Michael S Hershfield, Angus M Hucknall, Ashutosh Chilkoti