日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

KCNE1 induces fenestration in the Kv7.1/KCNE1 channel complex that allows for highly specific pharmacological targeting

KCNE1 诱导 Kv7.1/KCNE1 通道复合物的开窗,从而实现高度特异性的药物靶向作用

Eva Wrobel, Ina Rothenberg, Christoph Krisp, Franziska Hundt, Benjamin Fraenzel, Karina Eckey, Joannes T M Linders, David J Gallacher, Rob Towart, Lutz Pott, Michael Pusch, Tao Yang, Dan M Roden, Harley T Kurata, Eric Schulze-Bahr, Nathalie Strutz-Seebohm, Dirk Wolters, Guiscard Seebohm0

Structural interplay of KV7.1 and KCNE1 is essential for normal repolarization and is compromised in short QT syndrome 2 (KV7.1-A287T)

KV7.1 和 KCNE1 的结构相互作用对于正常复极至关重要,但在短 QT 综合征 2 (KV7.1-A287T) 中受到损害

Ina Rothenberg, Ilaria Piccini, Eva Wrobel, Birgit Stallmeyer, Jovanca Müller, Boris Greber, Nathalie Strutz-Seebohm, Eric Schulze-Bahr, Nicole Schmitt, Guiscard Seebohm

Structural basis of PI(4,5)P2-dependent regulation of GluA1 by phosphatidylinositol-5-phosphate 4-kinase, type II, alpha (PIP5K2A)

PI(4,5)P2 依赖性调节 GluA1 的结构基础,由 II 型磷脂酰肌醇-5-磷酸 4-激酶 α(PIP5K2A)实现

Guiscard Seebohm, Eva Wrobel, Michael Pusch, Markus Dicks, Jan Terhag, Veronika Matschke, Ina Rothenberg, Oana N Ursu, Fabian Hertel, Lutz Pott, Florian Lang, Eric Schulze-Bahr, Michael Hollmann, Raphael Stoll, Nathalie Strutz-Seebohm