日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Enhanced therapeutic potential of antibody fragment via IEDDA-mediated site-specific albumin conjugation

通过 IEDDA 介导的位点特异性白蛋白结合增强抗体片段的治疗潜力

Eun Byeol Go #, Jae Hun Lee #, Jeong Haeng Cho #, Na Hyun Kwon #, Jong-Il Choi, Inchan Kwon

In vivo study of newly developed albumin-conjugated urate oxidase for gout treatment

新开发的白蛋白结合尿酸氧化酶治疗痛风的体内研究

Jeonghaeng Cho #, Byungseop Yang #, Jae Hun Lee, Hyunwoo Kim, Hyeongseok Kim, Eun Byeol Go, Dong-Ho Bak, Su Jin Park, Inchan Kwon, Jong-Il Choi, Kyunghee Lee

Hydrogen-fueled CO2 reduction using oxygen-tolerant oxidoreductases

利用耐氧氧化还原酶进行氢燃料二氧化碳还原

Jaehyun Cha, Hyeonseon Bak, Inchan Kwon

Computation-Aided Design of Albumin Affibody-Inserted Antibody Fragment for the Prolonged Serum Half-Life

计算辅助设计白蛋白亲和体插入抗体片段以延长血清半衰期

Na Hyun Kwon, Jae Hun Lee, Inchan Kwon

Thermostable and Long-Circulating Albumin-Conjugated Arthrobacter globiformis Urate Oxidase

耐热、长循环白蛋白结合球形节杆菌尿酸氧化酶

Byungseop Yang, Inchan Kwon

Chemical Modification of Cysteine with 3-Arylpropriolonitrile Improves the In Vivo Stability of Albumin-Conjugated Urate Oxidase Therapeutic Protein

3-芳基丙腈对半胱氨酸进行化学修饰可提高白蛋白结合尿酸氧化酶治疗蛋白的体内稳定性

Byungseop Yang, Inchan Kwon

Recombinant Peptide Production Platform Coupled with Site-Specific Albumin Conjugation Enables a Convenient Production of Long-Acting Therapeutic Peptide

重组肽生产平台结合位点特异性白蛋白结合,可方便生产长效治疗肽

Mijeong Bak, Junyong Park, Kiyoon Min, Jinhwan Cho, Jihyoun Seong, Young S Hahn, Giyoong Tae, Inchan Kwon

Generation of therapeutic protein variants with the human serum albumin binding capacity via site-specific fatty acid conjugation

通过位点特异性脂肪酸结合生成具有人血清白蛋白结合能力的治疗性蛋白质变体

Jinhwan Cho, Sung In Lim, Byung Seop Yang, Young S Hahn, Inchan Kwon

Site-specific albumination of a therapeutic protein with multi-subunit to prolong activity in vivo

多亚基治疗性蛋白质的位点特异性白化以延长体内活性

Sung In Lim, Young S Hahn, Inchan Kwon

Suppressing mutation-induced protein aggregation in mammalian cells by mutating residues significantly displaced upon the original mutation

通过突变原始突变后明显移位的残基来抑制哺乳动物细胞中突变引起的蛋白质聚集

Simpson Gregoire, Kelly Glitzos, Inchan Kwon