Obesity promotes resistance to anti-VEGF therapy in breast cancer by up-regulating IL-6 and potentially FGF-2
肥胖通过上调IL-6和潜在的FGF-2，促进乳腺癌对VEGF抑制剂的耐药性。
期刊:Science Translational Medicine
影响因子:14.6
doi:10.1126/scitranslmed.aag0945
Incio, Joao; Ligibel, Jennifer A; McManus, Daniel T; Suboj, Priya; Jung, Keehoon; Kawaguchi, Kosuke; Pinter, Matthias; Babykutty, Suboj; Chin, Shan M; Vardam, Trupti D; Huang, Yuhui; Rahbari, Nuh N; Roberge, Sylvie; Wang, Dannie; Gomes-Santos, Igor L; Puchner, Stefan B; Schlett, Christopher L; Hoffmman, Udo; Ancukiewicz, Marek; Tolaney, Sara M; Krop, Ian E; Duda, Dan G; Boucher, Yves; Fukumura, Dai; Jain, Rakesh K
肿瘤
FGF-2
肿瘤免疫
EGF
乳腺癌
代谢
肥胖
VEGF
IL-6
