日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mutant p53 binds and controls estrogen receptor activity to drive endocrine resistance in ovarian cancer

突变型p53结合并控制雌激素受体活性,从而驱动卵巢癌的内分泌耐药性。

Shao, Chunlei; Indeglia, Alexandra; Foster, Maya; Casey, Kaitlyn; Leung, Jessica; Modarai, Shirin R; Leu, Julia I-Ju; Duong, Bryant; Mes-Masson, Anne-Marie; Sims-Mourtada, Jennifer; Auslander, Noam; Drapkin, Ronny; Bitler, Benjamin G; Zhang, Nan; Murphy, Maureen E

Protocol for identification of protein citrullination by immunoprecipitation followed by mass spectrometry.

利用免疫沉淀结合质谱法鉴定蛋白质瓜氨酸化的方案。

Indeglia Alexandra, Tang Hsin-Yao

Targeted citrullination enables p53 binding to non-canonical sites.

靶向瓜氨酸化使 p53 能够与非经典位点结合。

Indeglia Alexandra, Valdespino Andrea, Pantella Giulia, Offley Sarah, Hill Connor, Foster Maya, Casey Kaitlyn, Tang Hsin-Yao, Faustino Anneliese M, Gardini Alessandro, Murphy Maureen E

NAB2-STAT6 drives an EGR1-dependent neuroendocrine program in solitary fibrous tumors.

NAB2-STAT6 驱动孤立性纤维瘤中 EGR1 依赖性神经内分泌程序

Hill Connor, Indeglia Alexandra, Picone Francis, Murphy Maureen E, Cipriano Cara, Maki Robert G, Gardini Alessandro

Variation at the R181 residue of p53 confers loss of p53 DNA binding cooperativity with the retention of mitochondrial-associated apoptosis.

p53 R181 残基的变异导致 p53 DNA 结合协同作用丧失,但线粒体相关细胞凋亡仍得以保留

Moses Renyta, Indeglia Alexandra, Levine Alison S, Hausler Ryan, Kelly Gregory, Miller Sven A, Anez Isabel, Heller Melissa, Delgado Rosella, Orr Caitlin, Kohlmann Wendy, Naumer Anne, Vagher Jennie, Cahill Sophie R, Maese Luke D, Karanicolas John, Garber Judy E, Murphy Maureen E, Maxwell Kara N

Elucidating the chain of command: our current understanding of critical target genes for p53-mediated tumor suppression

阐明调控链:我们目前对p53介导的肿瘤抑制关键靶基因的理解

Indeglia, Alexandra; Murphy, Maureen E

Regulation of alternative polyadenylation isoforms of Timp2 is an effector event of RAS signaling in cell transformation

Timp2 的选择性多聚腺苷酸化异构体的调控是 RAS 信号通路在细胞转化中的效应事件。

Ai, Yuxi; Ding, Qingbao; Wan, Zezhong; Tyagi, Sanjay; Indeglia, Alexandra; Murphy, Maureen; Tian, Bin

Common activities and predictive gene signature identified for genetic hypomorphs of TP53

TP53基因低效突变体的共同活动和预测基因特征已确定

Leung, Jessica C; Leu, Julia I-Ju; Indeglia, Alexandra; Kannan, Toshitha; Clarke, Nicole L; Kirven, Nicole A; Dweep, Harsh; Garlick, David; Barnoud, Thibaut; Kossenkov, Andrew V; George, Donna L; Murphy, Maureen E

Shifting the paradigms for tumor suppression: lessons from the p53 field

转变肿瘤抑制范式:来自p53领域的启示

Barnoud, Thibaut; Indeglia, Alexandra; Murphy, Maureen E