Ines Bruno相关文献与解析，生知库 | 链接生命科学的每一步

Dafne Ruggiero, Emis Ingenito, Eleonora Boccia, Vincenzo Vestuto, Maria Rosaria Miranda, Stefania Terracciano, Gianluigi Lauro, Giuseppe Bifulco, Ines Bruno

Human

Caspase3

发表日期：2024

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Identification of Novel Bromodomain-Containing Protein 4 (BRD4) Binders through 3D Pharmacophore-Based Repositioning Screening Campaign

通过基于 3D 药效团的重新定位筛选活动鉴定新型含溴结构域蛋白 4 (BRD4) 结合剂

期刊:Molecules

影响因子:4.2

doi:10.3390/molecules29174025

Ester Colarusso, Erica Gazzillo, Eleonora Boccia, Stefania Terracciano, Ines Bruno, Giuseppe Bifulco, Maria Giovanna Chini, Gianluigi Lauro

Repositioning of Quinazolinedione-Based Compounds on Soluble Epoxide Hydrolase (sEH) through 3D Structure-Based Pharmacophore Model-Driven Investigation

通过基于 3D 结构的药效团模型驱动研究对可溶性环氧化物水解酶 (sEH) 上的喹唑啉二酮基化合物进行重新定位

期刊:Molecules

影响因子:4.2

doi:10.3390/molecules27123866

Erica Gazzillo, Stefania Terracciano, Dafne Ruggiero, Marianna Potenza, Maria Giovanna Chini, Gianluigi Lauro, Katrin Fischer, Robert Klaus Hofstetter, Assunta Giordano, Oliver Werz, Ines Bruno, Giuseppe Bifulco

3D/类器官

发表日期：2022

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Structural Refinement of 2,4-Thiazolidinedione Derivatives as New Anticancer Agents Able to Modulate the BAG3 Protein

2,4-噻唑烷二酮衍生物的结构精炼作为能够调节 BAG3 蛋白的新型抗癌剂

期刊:Molecules

影响因子:4.2

doi:10.3390/molecules27030665

Dafne Ruggiero, Stefania Terracciano, Gianluigi Lauro, Michela Pecoraro, Silvia Franceschelli, Giuseppe Bifulco, Ines Bruno

肿瘤

发表日期：2022

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Discovery of new molecular entities able to strongly interfere with Hsp90 C-terminal domain

发现能够强烈干扰 Hsp90 C 末端结构域的新分子实体

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-017-14902-y

Stefania Terracciano, Alessandra Russo, Maria G Chini, Maria C Vaccaro, Marianna Potenza, Antonio Vassallo, Raffaele Riccio, Giuseppe Bifulco, Ines Bruno

发表日期：2018

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Identification by Inverse Virtual Screening of magnolol-based scaffold as new tankyrase-2 inhibitors

通过逆向虚拟筛选鉴定基于厚朴酚的支架作为新型 tankyrase-2 抑制剂

期刊:Bioorganic & Medicinal Chemistry

影响因子:3.3

doi:10.1016/j.bmc.2018.06.019

Simone Di Micco, Luana Pulvirenti, Ines Bruno, Stefania Terracciano, Alessandra Russo, Maria C Vaccaro, Dafne Ruggiero, Vera Muccilli, Nunzio Cardullo, Corrado Tringali, Raffaele Riccio, Giuseppe Bifulco

信号转导

发表日期：2018

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Nanoradiopharmaceuticals for breast cancer imaging: development, characterization, and imaging in inducted animals

用于乳腺癌成像的纳米放射性药物：开发、表征和诱导动物成像

期刊:Oncotargets and Therapy

影响因子:2.8

doi:10.2147/OTT.S110787

Sarcinelli, Michelle Alvares; Albernaz, Marta de Souza; Szwed, Marzena; Iscaife, Alexandre; Leite, Kátia Ramos Moreira; Junqueira, Mara de Souza; Bernardes, Emerson Soares; da Silva, Emerson Oliveira; Tavares, Maria Ines Bruno; Santos-Oliveira, Ralph

9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain

9H-嘌呤支架揭示了 BRD9 溴结构域的诱导契合口袋可塑性

期刊:Journal of Medicinal Chemistry

影响因子:6.8

doi:10.1021/jm501893k

Sarah Picaud, Maria Strocchia, Stefania Terracciano, Gianluigi Lauro, Jacqui Mendez, Danette L Daniels, Raffaele Riccio, Giuseppe Bifulco, Ines Bruno, Panagis Filippakopoulos

BRD9

发表日期：2015

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Identification of a New Promising BAG3 Modulator Featuring the Imidazopyridine Scaffold

鉴定具有咪唑并吡啶骨架的新型有前景的 BAG3 调节剂

Identification of Novel Bromodomain-Containing Protein 4 (BRD4) Binders through 3D Pharmacophore-Based Repositioning Screening Campaign

通过基于 3D 药效团的重新定位筛选活动鉴定新型含溴结构域蛋白 4 (BRD4) 结合剂

Repositioning of Quinazolinedione-Based Compounds on Soluble Epoxide Hydrolase (sEH) through 3D Structure-Based Pharmacophore Model-Driven Investigation

通过基于 3D 结构的药效团模型驱动研究对可溶性环氧化物水解酶 (sEH) 上的喹唑啉二酮基化合物进行重新定位

Structural Refinement of 2,4-Thiazolidinedione Derivatives as New Anticancer Agents Able to Modulate the BAG3 Protein

2,4-噻唑烷二酮衍生物的结构精炼作为能够调节 BAG3 蛋白的新型抗癌剂

Discovery of new molecular entities able to strongly interfere with Hsp90 C-terminal domain

发现能够强烈干扰 Hsp90 C 末端结构域的新分子实体

Identification by Inverse Virtual Screening of magnolol-based scaffold as new tankyrase-2 inhibitors

通过逆向虚拟筛选鉴定基于厚朴酚的支架作为新型 tankyrase-2 抑制剂

Nanoradiopharmaceuticals for breast cancer imaging: development, characterization, and imaging in inducted animals

用于乳腺癌成像的纳米放射性药物：开发、表征和诱导动物成像

9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain

9H-嘌呤支架揭示了 BRD9 溴结构域的诱导契合口袋可塑性