BRAF Inhibitors Amplify the Proapoptotic Activity of MEK Inhibitors by Inducing ER Stress in NRAS-Mutant Melanoma
BRAF 抑制剂通过诱导 NRAS 突变型黑色素瘤中的 ER 应激来增强 MEK 抑制剂的促凋亡活性
期刊:Clinical Cancer Research
影响因子:10
doi:10.1158/1078-0432.CCR-17-0098
Heike Niessner, Tobias Sinnberg, Corinna Kosnopfel, Keiran S M Smalley, Daniela Beck, Christian Praetorius, Marion Mai, Stefan Beissert, Dagmar Kulms, Martin Schaller, Claus Garbe, Keith T Flaherty, Dana Westphal, Ines Wanke, Friedegund Meier
