Discovery of potent and selective inhibitors of human NLRP3 with a novel mechanism of action
发现具有全新作用机制的高效选择性人NLRP3抑制剂
期刊:Journal of Experimental Medicine
影响因子:12.6
doi:10.1084/jem.20242403
Kevin Wilhelmsen,Aditi Deshpande,Sarah Tronnes,Maitriyee Mahanta,Matthew Banicki,Mary Cochran,Samantha Cowdin,Kristen Fortney,George Hartman,Robert E Hughes,Rusty Montgomery,Claudia P Portillo,Paul Rubin,Taiz Salazar,Yan Wang,Shijun Yan,Barry A Morgan,Assem Duisembekova,Romane Riou,Michael Marleaux,Inga V Hochheiser,Hannes Buthmann,Dominic Ferber,Jane Torp,Wei Wang,Melanie Cranston,Chloe M McKee,Thea J Mawhinney,Emma C McKay,Fehime K Eroglu,Jasmin Kümmerle-Deschner,Alexander N R Weber,Bénédicte F Py,Matthias Geyer,Rebecca C Coll