Ingelman-Sundberg相关文献与解析，生知库

Pharmacokinetic recall study of Estonian Biobank participants with novel genetic variants in CYP2C19 and CYP2D6

对携带 CYP2C19 和 CYP2D6 新基因变异的爱沙尼亚生物库参与者进行药代动力学回忆研究

Krebs, Kristi; Luitva, Laura Birgit; Kõre, Anette Caroline; Kokasaar, Raul; Jõeloo, Maarja; Hudjashov, Georgi; Maal, Kadri; Størset, Elisabet; Wollmann, Birgit Malene; Karo-Astover, Liis; Fischer, Krista; Team, Estonian Biobank Research; Lauschke, Volker M; Ingelman-Sundberg, Magnus; Molden, Espen; Irs, Alar; Oselin, Kersti; Lass, Jana; Milani, Lili

发表日期：2026

文献求助收藏

A Long-Term Human Liver Spheroid Model for Assessing Silencing and Durability of GalNAc-Conjugated siRNAs

用于评估 GalNAc 偶联 siRNA 沉默效果和持久性的长期人肝球体模型

期刊:Cts-Clinical and Translational Science

影响因子:2.8

doi:10.1111/cts.70536

Scholten, Gijs-Jan; Grundmann, Clara; Nordling, Åsa; Coskun, Caroline; Engelhardt, Volker; Sadhasivam, Lingheswar; Einfalt, Tomaž; Ingelman-Sundberg, Magnus; van Riet, Sander

Human

发表日期：2026

文献求助收藏

Improved Prediction of CYP2D6 Catalyzed Drug Metabolism by Taking Variant Substrate Specificities and Novel Polymorphic Haplotypes into Account

通过考虑底物特异性变异和新型多态性单倍型，改进对CYP2D6催化药物代谢的预测。

期刊:Clinical Pharmacology & Therapeutics

影响因子:5.5

doi:10.1002/cpt.3680

Johansson, Inger; Xanthopoulou, Emmanouella M; Zhou, Yitian; Sanchez-Spitman, Anabel; van der Lee, Maaike; Wollmann, Birgit M; Størset, Elisabet; Swen, Jesse J; Guchelaar, Henk-Jan; Molden, Espen; Jukic, Marin M; Ingelman-Sundberg, Magnus

代谢

发表日期：2025

文献求助收藏

Impact of the transcription factor nuclear factor 1 B T>C polymorphism on clozapine metabolism in vivo and expression of intestinal transporters in vitro

转录因子核因子1B T>C多态性对体内氯氮平代谢及体外肠道转运蛋白表达的影响

期刊:Drug Metabolism and Disposition

影响因子:4

doi:10.1016/j.dmd.2025.100100

Solbakk, Maria; Smith, Robert Løvsletten; Wollmann, Birgit M; Bråten, Line Skute; Johansson, Inger; Ingelman-Sundberg, Magnus; Andreassen, Ole A; Molden, Espen

代谢

发表日期：2025

文献求助收藏

Pharmacogenetic Variants and Plasma Concentrations of Antiseizure Drugs: A Systematic Review and Meta-Analysis

抗癫痫药物的药理遗传变异与血浆浓度：系统评价和荟萃分析

期刊:Jama Network Open

影响因子:9.7

doi:10.1001/jamanetworkopen.2024.25593

Milosavljevic, Filip; Manojlovic, Marina; Matkovic, Lena; Molden, Espen; Ingelman-Sundberg, Magnus; Leucht, Stefan; Jukic, Marin M

Systemic and mucosal adaptive immunity to SARS-CoV-2 during the Omicron wave in patients with chronic lymphocytic leukemia

慢性淋巴细胞白血病患者在 SARS-CoV-2 奥密克戎疫情期间的系统性和黏膜适应性免疫

期刊:Haematologica

影响因子:7.9

doi:10.3324/haematol.2023.282894

Ingelman-Sundberg, Hanna M; Blixt, Lisa; Wullimann, David; Wu, Jinghua; Gao, Yu; Healy, Katie; Muschiol, Sandra; Bogdanovic, Gordana; Åberg, Mikael; Kjellander, Christian; Grifoni, Alba; Sette, Alessandro; Aleman, Soo; Chen, Puran; Blennow, Ola; Hansson, Lotta; Ljunggren, Hans-Gustaf; Chen, Margaret Sällberg; Buggert, Marcus; Österborg, Anders

The role of sinusoidal endothelial cells and TIMP1 in the regulation of fibrosis in a novel human liver 3D NASH model

肝窦内皮细胞和TIMP1在新型人肝3D NASH模型中纤维化调控中的作用

期刊:Hepatology Communications

影响因子:4.6

doi:10.1097/HC9.0000000000000374

van Riet, Sander; Julien, Anais; Atanasov, Andrea; Nordling, Åsa; Ingelman-Sundberg, Magnus

Mechanisms of 5-HT receptor antagonists in the regulation of fibrosis in a 3D human liver spheroid model

5-HT 受体拮抗剂在 3D 人肝球模型中调节纤维化的机制

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-023-49240-9

Sara Redenšek Trampuž, Sander van Riet, Åsa Nordling, Magnus Ingelman-Sundberg

The evolving landscape of pharmacogenomics: Current achievements and future directions

药物基因组学的发展现状：当前成就与未来方向

Dietary-Driven Gene Expansion

饮食驱动的基因扩增

Pharmacokinetic recall study of Estonian Biobank participants with novel genetic variants in CYP2C19 and CYP2D6

对携带 CYP2C19 和 CYP2D6 新基因变异的爱沙尼亚生物库参与者进行药代动力学回忆研究

A Long-Term Human Liver Spheroid Model for Assessing Silencing and Durability of GalNAc-Conjugated siRNAs

用于评估 GalNAc 偶联 siRNA 沉默效果和持久性的长期人肝球体模型

Improved Prediction of CYP2D6 Catalyzed Drug Metabolism by Taking Variant Substrate Specificities and Novel Polymorphic Haplotypes into Account

通过考虑底物特异性变异和新型多态性单倍型，改进对CYP2D6催化药物代谢的预测。

Impact of the transcription factor nuclear factor 1 B T>C polymorphism on clozapine metabolism in vivo and expression of intestinal transporters in vitro

转录因子核因子1B T>C多态性对体内氯氮平代谢及体外肠道转运蛋白表达的影响

Pharmacogenetic Variants and Plasma Concentrations of Antiseizure Drugs: A Systematic Review and Meta-Analysis

抗癫痫药物的药理遗传变异与血浆浓度：系统评价和荟萃分析

Systemic and mucosal adaptive immunity to SARS-CoV-2 during the Omicron wave in patients with chronic lymphocytic leukemia

慢性淋巴细胞白血病患者在 SARS-CoV-2 奥密克戎疫情期间的系统性和黏膜适应性免疫

The role of sinusoidal endothelial cells and TIMP1 in the regulation of fibrosis in a novel human liver 3D NASH model

肝窦内皮细胞和TIMP1在新型人肝3D NASH模型中纤维化调控中的作用

Mechanisms of 5-HT receptor antagonists in the regulation of fibrosis in a 3D human liver spheroid model

5-HT 受体拮抗剂在 3D 人肝球模型中调节纤维化的机制