A laminin 511 matrix is regulated by TAZ and functions as the ligand for the α6Bβ1 integrin to sustain breast cancer stem cells
层粘连蛋白511基质受TAZ调控,并作为α6Bβ1整合素的配体,维持乳腺癌干细胞的活性。
期刊:Genes & Development
影响因子:7.7
doi:10.1101/gad.253682.114
Chang, Cheng; Goel, Hira Lal; Gao, Huijie; Pursell, Bryan; Shultz, Leonard D; Greiner, Dale L; Ingerpuu, Sulev; Patarroyo, Manuel; Cao, Shiliang; Lim, Elgene; Mao, Junhao; McKee, Karen Kulju; Yurchenco, Peter D; Mercurio, Arthur M
肿瘤
发育与干细胞
肿瘤免疫
信号转导
乳腺癌
干细胞
细胞生物学
TAZ