日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Modulation of the mechanism of action of antibacterial silver N-heterocyclic carbene complexes by variation of the halide ligand

通过改变卤化物配体来调节抗菌银 N-杂环卡宾配合物的作用机理

Igor V Esarev, Ingo Ott

Paraptotic Cell Death as an Unprecedented Mode of Action Observed for New Bipyridine-Silver(I) Compounds Bearing Phosphane Coligands

观察到带有磷烷共配体的新型联吡啶-银 (I) 化合物具有前所未有的作用方式,即旁凋亡细胞死亡

Ricardo G Teixeira, Alessia Stefanelli, Adhan Pilon, Rebecca Warmers, Xavier Fontrodona, Isabel Romero, Paulo J Costa, Maria J Villa de Brito, Xenia Hudec, Christine Pirker, Sebastian Türck, Alexandra M M Antunes, Christian R Kowol, Ingo Ott, Anamaria Brozovic, Andy Sombke, Margret Eckhard, Ana Isab

Silver Organometallics that are Highly Potent Thioredoxin and Glutathione Reductase Inhibitors: Exploring the Correlations of Solution Chemistry with the Strong Antibacterial Effects

银有机金属化合物是强效硫氧还蛋白和谷胱甘肽还原酶抑制剂:探索溶液化学与强抗菌作用的相关性

Igor V Esarev, Bianka Karge, Haoxuan Zeng, Petra Lippmann, Peter G Jones, Hedda Schrey, Mark Brönstrup, Ingo Ott

An organometallic hybrid antibiotic of metronidazole with a Gold(I) N-Heterocyclic Carbene overcomes metronidazole resistance in Clostridioides difficile

甲硝唑与金(I)N-杂环卡宾的有机金属杂化抗生素可克服艰难梭菌对甲硝唑的耐药性

Rolf Büssing, Arne Bublitz, Bianka Karge, Mark Brönstrup, Till Strowig, Ingo Ott

Silver N-heterocyclic carbene complexes are potent uncompetitive inhibitors of the papain-like protease with antiviral activity against SARS-CoV-2

银 N-杂环卡宾复合物是木瓜蛋白酶样蛋白酶的强效非竞争性抑制剂,具有抗 SARS-CoV-2 病毒活性

Maria Gil-Moles, Cillian O'Beirne, Igor V Esarev, Petra Lippmann, Matthias Tacke, Jindrich Cinatl Jr, Denisa Bojkova, Ingo Ott

A biscarbene gold(I)-NHC-complex overcomes cisplatin-resistance in A2780 and W1 ovarian cancer cells highlighting pERK as regulator of apoptosis

双卡宾金(I)-NHC 复合物可克服 A2780 和 W1 卵巢癌细胞中的顺铂耐药性,突出 pERK 作为细胞凋亡调节剂的作用

Philipp König, Roman Zhulenko, Eloy Suparman, Henrik Hoffmeister, Nico Bückreiß, Ingo Ott, Gerd Bendas

Photosubstitution in a trisheteroleptic ruthenium complex inhibits conjunctival melanoma growth in a zebrafish orthotopic xenograft model

三异质钌复合物的光替代作用可抑制斑马鱼原位异种移植模型中结膜黑色素瘤的生长

Quanchi Chen ,Jordi-Amat Cuello-Garibo ,Ludovic Bretin ,Liyan Zhang ,Vadde Ramu ,Yasmin Aydar ,Yevhen Batsiun ,Sharon Bronkhorst ,Yurii Husiev ,Nataliia Beztsinna ,Lanpeng Chen ,Xue-Quan Zhou ,Claudia Schmidt ,Ingo Ott ,Martine J Jager ,Albert M Brouwer ,B Ewa Snaar-Jagalska ,Sylvestre Bonnet

Effects of 4-Br-A23187 on Bacillus subtilis cells and unilamellar vesicles reveal it to be a potent copper ionophore

4-Br-A23187 对枯草芽孢杆菌细胞和单层囊泡的影响表明它是一种有效的铜离子载体

Christoph H R Senges, Helen L Warmuth, Melissa Vázquez-Hernández, Huriye Deniz Uzun, Leonie Sagurna, Pascal Dietze, Claudia Schmidt, Brix Mücher, Stefan Herlitze, Ute Krämer, Ingo Ott, Thomas Günther Pomorski, Julia E Bandow

Rollover Cyclometalation vs Nitrogen Coordination in Tetrapyridyl Anticancer Gold(III) Complexes: Effect on Protein Interaction and Toxicity

四吡啶抗癌金(III)配合物中的翻转环金属化与氮配位:对蛋白质相互作用和毒性的影响

Xue-Quan Zhou, Imma Carbo-Bague, Maxime A Siegler, Jonathan Hilgendorf, Uttara Basu, Ingo Ott, Rongfang Liu, Liyan Zhang, Vadde Ramu, Adriaan P IJzerman, Sylvestre Bonnet

Evaluation of Ruthenium(II) N-Heterocyclic Carbene Complexes as Antibacterial Agents and Inhibitors of Bacterial Thioredoxin Reductase

评估钌 (II) N-杂环卡宾配合物作为抗菌剂和细菌硫氧还蛋白还原酶抑制剂的作用

Hilke Burmeister, Pascal Dietze, Lutz Preu, Julia E Bandow, Ingo Ott