Notch1 blockade by a novel, selective anti-Notch1 neutralizing antibody improves immunotherapy efficacy in melanoma by promoting an inflamed TME.
一种新型的选择性抗 Notch1 中和抗体通过促进炎症性肿瘤微环境 (TME) 来阻断 Notch1，从而提高黑色素瘤免疫疗法的疗效
期刊:Journal of Experimental & Clinical Cancer Research
影响因子:12.8
doi:10.1186/s13046-024-03214-5
de Freitas Juliano Tiburcio, Thakur Varsha, LaPorte Kathryn M, Thakur Vijay S, Flores Brian, Caicedo Valentina, Ajaegbu Chioma G E, Ingrasci Giuseppe, Lipman Zoe M, Zhang Keman, Qiu Hong, Malek Thomas R, Bedogni Barbara
