日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Decreased ATP production and myocardial contractile reserve in metabolic heart disease

代谢性心脏病中ATP生成减少和心肌收缩储备下降

Luptak, Ivan; Sverdlov, Aaron L; Panagia, Marcello; Qin, Fuzhong; Pimentel, David R; Croteau, Dominique; Siwik, Deborah A; Ingwall, Joanne S; Bachschmid, Markus M; Balschi, James A; Colucci, Wilson S

Creatine--a dispensable metabolite?

肌酸——一种可有可无的代谢物?

Taegtmeyer, Heinrich; Ingwall, Joanne S

Myosin-driven rescue of contractile reserve and energetics in mouse hearts bearing familial hypertrophic cardiomyopathy-associated mutant troponin T is mutation-specific

在携带家族性肥厚型心肌病相关突变型肌钙蛋白T的小鼠心脏中,肌球蛋白驱动的收缩储备和能量代谢的恢复具有突变特异性。

He, Huamei; Hoyer, Kirsten; Tao, Hai; Rice, Ronald; Jimenez, Jesus; Tardiff, Jil C; Ingwall, Joanne S

Study design for the Immediate Myocardial Metabolic Enhancement During Initial Assessment and Treatment in Emergency Care (IMMEDIATE) Trial: A double-blind randomized controlled trial of intravenous glucose, insulin, and potassium for acute coronary syndromes in emergency medical services

急诊护理中初始评估和治疗期间即刻心肌代谢增强(IMMEDIATE)试验的研究设计:一项针对急诊医疗服务中急性冠脉综合征患者静脉注射葡萄糖、胰岛素和钾的双盲随机对照试验

Selker, Harry P; Beshansky, Joni R; Griffith, John L; D'Agostino, Ralph B; Massaro, Joseph M; Udelson, James E; Rashba, Eric J; Ruthazer, Robin; Sheehan, Patricia R; Desvigne-Nickens, Patrice; Rosenberg, Yves D; Atkins, James M; Sayah, Assaad J; Aufderheide, Tom P; Rackley, Charles E; Opie, Lionel H; Lambrew, Costas T; Cobb, Leonard A; Macleod, Bruce A; Ingwall, Joanne S; Zalenski, Robert J; Apstein, Carl S

Rearrangement of energetic and substrate utilization networks compensate for chronic myocardial creatine kinase deficiency

能量和底物利用网络的重组可补偿慢性心肌肌酸激酶缺乏症。

Dzeja, Petras P; Hoyer, Kirsten; Tian, Rong; Zhang, Song; Nemutlu, Emirhan; Spindler, Matthias; Ingwall, Joanne S

Compromised myocardial energetics in hypertrophied mouse hearts diminish the beneficial effect of overexpressing SERCA2a

肥大小鼠心脏中受损的心肌能量代谢会减弱SERCA2a过表达的有益作用。

Pinz, Ilka; Tian, Rong; Belke, Darrell; Swanson, Eric; Dillmann, Wolfgang; Ingwall, Joanne S

Progressive loss of creatine maintains a near normal DeltaG approximately (ATP) in transgenic mouse hearts with cardiomyopathy caused by overexpressing Gsalpha

在因Gsalpha过度表达而导致心肌病的转基因小鼠心脏中,肌酸的进行性丢失维持着接近正常的ΔG<sub>a</sub>(ATP)值。

Shen, Weiqun; Vatner, Dorothy E; Vatner, Stephen F; Ingwall, Joanne S

Cardiac myosin heavy chain isoform exchange alters the phenotype of cTnT-related cardiomyopathies in mouse hearts.

心肌肌球蛋白重链同工型交换改变了小鼠心脏中 cTnT 相关心肌病的表型

Rice Ron, Guinto Pia, Dowell-Martino Candice, He Huamei, Hoyer Kirsten, Krenz Maike, Robbins Jeffrey, Ingwall Joanne S, Tardiff Jil C

Early beneficial effects of bone marrow-derived mesenchymal stem cells overexpressing Akt on cardiac metabolism after myocardial infarction

骨髓间充质干细胞过表达Akt对心肌梗死后心脏代谢的早期有益作用

Gnecchi, Massimiliano; He, Huamei; Melo, Luis G; Noiseaux, Nicolas; Morello, Fulvio; de Boer, Rudolf A; Zhang, Lunan; Pratt, Richard E; Dzau, Victor J; Ingwall, Joanne S

Aberrant activation of AMP-activated protein kinase remodels metabolic network in favor of cardiac glycogen storage

AMP激活蛋白激酶的异常激活会重塑代谢网络,使其有利于心脏糖原的储存。

Luptak, Ivan; Shen, Mei; He, Huamei; Hirshman, Michael F; Musi, Nicolas; Goodyear, Laurie J; Yan, Jie; Wakimoto, Hiroko; Morita, Hiroyuki; Arad, Michael; Seidman, Christine E; Seidman, J G; Ingwall, Joanne S; Balschi, James A; Tian, Rong