Targeted deletion of CD244 on monocytes promotes differentiation into anti-tumorigenic macrophages and potentiates PD-L1 blockade in melanoma
靶向敲除单核细胞上的CD244可促进其分化为抗肿瘤巨噬细胞，并增强PD-L1阻断在黑色素瘤中的作用。
期刊:Molecular Cancer
影响因子:33.9
doi:10.1186/s12943-024-01936-w
Kim, Jeongsoo; Kim, Tae-Jin; Chae, Sehyun; Ha, Hyojeong; Park, Yejin; Park, Sunghee; Yoon, Chul Joo; Lim, Seon Ah; Lee, Hyemin; Kim, Jiyoung; Kim, Jungwon; Im, Kyungtaek; Lee, Kyunghye; Kim, Jeongmin; Kim, Daham; Lee, Eunju; Shin, Min Hwa; Park, Serk In; Rhee, Inmoo; Jung, Keehoon; Lee, Jeewon; Lee, Keun Hwa; Hwang, Daehee; Lee, Kyung-Mi
巨噬细胞
黑色素瘤
肿瘤
肿瘤免疫
巨噬细胞
CD24
PD-L1
CD244
单核细胞
细胞生物学
CD2
免疫/内分泌
