日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

IL-2 silencing enables Tfh cell expansion during vaccination but is redundant for antibody production.

IL-2 沉默可促进疫苗接种期间 Tfh 细胞的扩增,但对抗体产生而言是多余的。

Innocentin Silvia, McKenzie Ross, Assalaarachchi Jayalini, Carslaw Helena A, Gupta Anusha, Cole Sanne, Liston Adrian, Linterman Michelle A, Webb Louise, Burton Alice R

Lung B cells in ectopic germinal centers undergo affinity maturation.

异位生发中心的肺B细胞发生亲和力成熟

Guillaume Stephane M, Foster William S, San Martín Molina Isabel, Watson Emily M, Innocentin Silvia, Kennedy Grant M, Denton Alice E, Linterman Michelle A

Improved Resolution of Influenza Vaccination Responses With High-Throughput Live Virus Microneutralisation.

利用高通量活病毒微中和法提高流感疫苗接种反应的分辨率

Adams Lorin, Stevenson-Leggett Phoebe, Lee Jia Le, Bazire James, Dowgier Giulia, Hobbs Agnieszka, Roustan Chloë, Borg Annabel, Carr Christine, Innocentin Silvia, Webb Louise M C, Smith Callie, Bawumia Philip, Lewis Nicola, O'Reilly Nicola, Kjaer Svend, Linterman Michelle A, Harvey Ruth, Wu Mary Y, Carr Edward J

Germinal center formation is resilient to CD69 deletion on T follicular helper cells

生发中心的形成不受滤泡辅助性T细胞上CD69缺失的影响。

Stephane M Guillaume ,Helena A Carslaw ,Silvia Innocentin ,Louise M C Webb ,Adrian Liston ,William S Foster ,Michelle A Linterman

Accelerated waning of the humoral response to COVID-19 vaccines in obesity

肥胖患者对 COVID-19 疫苗的体液反应加速减弱

Agatha A van der Klaauw, Emily C Horner #, Pehuén Pereyra-Gerber #, Utkarsh Agrawal #, William S Foster, Sarah Spencer, Bensi Vergese, Miriam Smith, Elana Henning, Isobel D Ramsay, Jack A Smith, Stephane M Guillaume, Hayley J Sharpe, Iain M Hay, Sam Thompson, Silvia Innocentin, Lucy H Booth, Chris R

Spatial dysregulation of T follicular helper cells impairs vaccine responses in aging

滤泡辅助性T细胞的空间失调会损害老年人的疫苗反应

Alyssa Silva-Cayetano ,Sigrid Fra-Bido ,Philippe A Robert ,Silvia Innocentin ,Alice R Burton ,Emily M Watson ,Jia Le Lee ,Louise M C Webb ,William S Foster ,Ross C J McKenzie ,Alexandre Bignon ,Ine Vanderleyden ,Dominik Alterauge ,Julia P Lemos ,Edward J Carr ,Danika L Hill ,Isabella Cinti ,Karl Balabanian ,Dirk Baumjohann ,Marion Espeli ,Michael Meyer-Hermann ,Alice E Denton ,Michelle A Linterman

B Cells from Aged Mice Do Not Have Intrinsic Defects in Affinity Maturation in Response to Immunization

老年小鼠的B细胞在免疫接种后,其亲和力成熟过程并无内在缺陷

Jia Le Lee ,Silvia Innocentin ,Alyssa Silva-Cayetano ,Stephane M Guillaume ,Michelle A Linterman

Targeting TLR4 during vaccination boosts MAdCAM-1+ lymphoid stromal cell activation and promotes the aged germinal center response

疫苗接种期间靶向 TLR4 可增强 MAdCAM-1+ 淋巴基质细胞活化并促进老化生发中心反应

Alice E Denton, James Dooley, Isabella Cinti, Alyssa Silva-Cayetano, Sigrid Fra-Bido, Silvia Innocentin, Danika L Hill, Edward J Carr, Andrew N J McKenzie, Adrian Liston, Michelle A Linterman

Tfh cells and the germinal center are required for memory B cell formation & humoral immunity after ChAdOx1 nCoV-19 vaccination

接种 ChAdOx1 nCoV-19 疫苗后,Tfh 细胞和生发中心是记忆 B 细胞形成和体液免疫所必需的。

William S Foster ,Jia Le Lee ,Nazia Thakur ,Joseph Newman ,Alexandra J Spencer ,Sophie Davies ,Danielle Woods ,Leila Godfrey ,Iain M Hay ,Silvia Innocentin ,Juan Carlos Yam-Puc ,Emily C Horner ,Hayley J Sharpe ,James E Thaventhiran ,Dalan Bailey ,Teresa Lambe ,Michelle A Linterman

B cell-intrinsic changes with age do not impact antibody-secreting cell formation but delay B cell participation in the germinal centre reaction

B细胞内在特性随年龄的变化并不影响抗体分泌细胞的形成,但会延迟B细胞参与生发中心反应。

Jia Le Lee ,Sigrid C Fra-Bido ,Alice R Burton ,Silvia Innocentin ,Danika L Hill ,Michelle A Linterman