日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Conformational biosensors delineate endosomal G protein regulation by GPCRs

构象生物传感器揭示了GPCR对内体G蛋白的调控作用

Wysolmerski, Brian; Fisher, Nicole M; Dates, Andrew N; Inoue, Asuka; Blythe, Emily E; von Zastrow, Mark

Mechanistic insights into the therapeutic properties of delta opioid receptor

对δ阿片受体治疗特性的机制性见解

Bernhard, Sarah M; Roy Chowdhury, Susovan; Murata, Tsuyoshi; Reinl, Erin L; Ramos-Gonzalez, Nokomis; Denn, Elizabeth; Appourchaux, Kevin; Inoue, Asuka; England, Sarah K; Fay, Jonathan F; Majumdar, Susruta; Chanda, Baron; Che, Tao

Mast cell-specific CysLT2 receptor signaling inhibits cysteinyl leukotriene-dependent mast cell activation and type 2 allergic lung inflammation.

肥大细胞特异性CysLT2受体信号传导抑制半胱氨酰白三烯依赖性肥大细胞活化和2型过敏性肺部炎症。

Nagai Jun, Hastings Madeline M, Nishida Airi, Majumdar Sreyashi, Zaleski Kendall, Marshall Sofia A, Lin Junrui, Saliman Mira A S, Tani Yumi, Murakami Yamato, Feng Chunli, Perniss Alexander, Wong Caitlin, Bankova Lora G, Inoue Asuka, Barrett Nora A, Boyce Joshua A

Re-evaluating Gα protein-response element specificity in GPCR signaling

重新评估GPCR信号传导中Gα蛋白反应元件的特异性

Saito, Ayaki; Kise, Ryoji; Yamaguchi, So; Yanagawa, Masataka; Inoue, Asuka

Gβγ engages PLCβ3 at multiple sites to reorient and facilitate its activation

Gβγ 与 PLCβ3 的多个位点结合,使其重新定向并促进其激活。

Fisher, Isaac J; Senarath, Kanishka; Outlaw, Kennedy; Muralidharan, Kaushik; Garland-Kuntz, Elisabeth E; Van Camp, Michelle; Komay, Tommy; Inoue, Asuka; Kostenis, Eva; Lambert, Nevin A; Lyon, Angeline M

Dietary anthocyanidin pelargonidin activates G protein-coupled receptor 35

膳食花青素天竺葵素激活G蛋白偶联受体35

Nakashima, Fumie; Shimomura, Sayako; Wakabayashi, Mayuka; Loh, Wei Qi; Ando, Harumi; Sei, Haruka; Hattori, Hiroyuki; Utomo, Didik Huswo; Kita, Masaki; Inoue, Asuka; Uchida, Koji; Shibata, Takahiro

Designing allosteric modulators to change GPCR G protein subtype selectivity

设计变构调节剂以改变GPCR G蛋白亚型选择性

Moore, Madelyn N; Person, Kelsey L; Robleto, Valeria L; Alwin, Abigail R; Krusemark, Campbell L; Foster, Noah; Ray, Caroline; Inoue, Asuka; Jackson, Michael R; Sheedlo, Michael J; Barak, Lawrence S; Marron Fernandez de Velasco, Ezequiel; Olson, Steven H; Slosky, Lauren M

Multi-faceted roles of β-arrestins in G protein-coupled receptor endocytosis

β-arrestin在G蛋白偶联受体内吞作用中的多重作用

Liu, Junke; Xue, Li; Ravier, Magalie A; Eshak, Floriane; Acher, Francine C; Goupil-Lamy, Anne; Cimadevila, Marta; Drube, Julia; Hoffmann, Carsten; Inoue, Asuka; Trinquet, Eric; Dupuis, Elodie; Prézeau, Laurent; Pin, Jean-Philippe; Rondard, Philippe

Single-molecule methods for characterizing receptor dimers reveal metastable opioid receptor homodimers that induce functional modulation

用于表征受体二聚体的单分子方法揭示了能够诱导功能调节的亚稳态阿片受体同源二聚体。

Zhou, Peng; Tsunoyama, Taka A; Kasai, Rinshi S; Hirosawa, Koichiro M; Kalay, Ziya; Aladag, Amine; Fujiwara, Takahiro K; Yokoyama, Tatsushi; Sakamoto, Masayuki; Kise, Ryoji; Yanagawa, Masataka; Inoue, Asuka; Pigolotti, Simone; Kusumi, Akihiro

Structural and dynamic insights into the biased signaling mechanism of the human kappa opioid receptor

对人类κ阿片受体偏向性信号传导机制的结构和动力学研究

Suno-Ikeda, Chiyo; Nishikawa, Ryo; Suzuki, Riko; Yokoi, Shun; Iwata, Seiya; Takai, Tomoyo; Ogura, Takaya; Hirose, Mika; Tokuda, Akihisa; Katamoto, Risako; Inoue, Akitoshi; Asai, Eri; Kise, Ryoji; Sugita, Yukihiko; Kato, Takayuki; Nagase, Hiroshi; Mitsutake, Ayori; Saitoh, Tsuyoshi; Katayama, Kota; Inoue, Asuka; Kandori, Hideki; Kobayashi, Takuya; Suno, Ryoji