Intagliata Sebastiano相关文献与解析，生知库

Citi, Valentina; Fallica, Antonino N; Salerno, Loredana; Virzì, Nicola F; Ciaffaglione, Valeria; Intagliata, Sebastiano; Veneziano, Sara; Benedetti, Giada; Spezzini, Jacopo; Martelli, Alma; Calderone, Vincenzo; Pittalà, Valeria

发表日期：2026

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Haloperidol drug repurposing unveils ferroptosis involvement in breast cancer cells.

氟哌啶醇药物再利用揭示了铁死亡在乳腺癌细胞中的作用

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-025-12645-9

Consoli Valeria, Sorrenti Valeria, Saccone Salvatore, Federico Concetta, Bruno Francesca, Cristaldi Domenico Andrea, PittalÃ Valeria, Intagliata Sebastiano, Vanella Luca

Synthesis and in Vitro Evaluation of CAPE Derivatives as Ferroptosis Inducers in Triple Negative Breast Cancer

CAPE衍生物作为三阴性乳腺癌铁死亡诱导剂的合成及体外评价

期刊:ACS Medicinal Chemistry Letters

影响因子:4

doi:10.1021/acsmedchemlett.4c00099

Consoli, Valeria; Fallica, Antonino N; Virzì, Nicola F; Salerno, Loredana; Intagliata, Sebastiano; Sorrenti, Valeria; Greish, Khaled; Giuffrida, Alessandro; Vanella, Luca; Pittalà, Valeria

The Inhibition of Neuropathic Pain Incited by Nerve Injury and Accompanying Mood Disorders by New Heme Oxygenase-1 Inducers: Mechanisms Implicated

新型血红素加氧酶-1诱导剂对神经损伤引起的神经性疼痛及伴随情绪障碍的抑制作用：相关机制

期刊:Antioxidants

影响因子:6.6

doi:10.3390/antiox12101859

Suárez-Rojas, Irene; Pérez-Fernández, Montse; Bai, Xue; Martínez-Martel, Ignacio; Intagliata, Sebastiano; Pittalà, Valeria; Salerno, Loredana; Pol, Olga

Examination of the Novel Sigma-1 Receptor Antagonist, SI 1/28, for Antinociceptive and Anti-allodynic Efficacy against Multiple Types of Nociception with Fewer Liabilities of Use

对新型Sigma-1受体拮抗剂SI 1/28进行镇痛和抗异位痛疗效研究，以评估其对多种类型伤害性疼痛的疗效和使用风险。

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms23020615

Wilson, Lisa L; Eans, Shainnel O; Ramadan-Siraj, Insitar; Modica, Maria N; Romeo, Giuseppe; Intagliata, Sebastiano; McLaughlin, Jay P

信号转导

发表日期：2022

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Characterization of CM-398, a Novel Selective Sigma-2 Receptor Ligand, as a Potential Therapeutic for Neuropathic Pain

CM-398（一种新型选择性Sigma-2受体配体）的特性分析及其作为神经性疼痛潜在治疗药物的价值

期刊:Molecules

影响因子:4.6

doi:10.3390/molecules27113617

Wilson, Lisa L; Alleyne, Amy R; Eans, Shainnel O; Cirino, Thomas J; Stacy, Heather M; Mottinelli, Marco; Intagliata, Sebastiano; McCurdy, Christopher R; McLaughlin, Jay P

信号转导

发表日期：2022

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UPLC-MS/MS method for the quantification of MCI-77, a novel sigma-1 receptor ligand, and its application to pharmacokinetic studies

采用超高效液相色谱-串联质谱法定量分析新型σ-1受体配体MCI-77，并将其应用于药代动力学研究

期刊:Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences

影响因子:2.8

doi:10.1016/j.jchromb.2022.123187

Popa, Raluca; Kamble, Shyam H; Kanumuri, Raju S; King, Tamara I; Berthold, Erin C; Intagliata, Sebastiano; Sharma, Abhisheak; McCurdy, Christopher R

信号转导

发表日期：2022

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Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective

Sigma受体配体作为细胞毒性药物的最新进展：药物化学视角

期刊:Journal of Medicinal Chemistry

影响因子:6.8

doi:10.1021/acs.jmedchem.0c02265

Fallica, Antonino N; Pittalà, Valeria; Modica, Maria N; Salerno, Loredana; Romeo, Giuseppe; Marrazzo, Agostino; Helal, Mohamed A; Intagliata, Sebastiano

Development of New Benzylpiperazine Derivatives as σ(1) Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects

开发新型苄基哌嗪衍生物作为σ(1)受体配体，并研究其体内镇痛和抗异位痛作用

期刊:ACS Chemical Neuroscience

影响因子:3.9

doi:10.1021/acschemneuro.1c00106

Romeo, Giuseppe; Bonanno, Federica; Wilson, Lisa L; Arena, Emanuela; Modica, Maria N; Pittalà, Valeria; Salerno, Loredana; Prezzavento, Orazio; McLaughlin, Jay P; Intagliata, Sebastiano

信号转导

发表日期：2021

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Mutual Prodrugs of 5-Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs

5-氟尿嘧啶的互惠前药：从经典的化疗药物到新型潜在抗癌药物

期刊:ChemMedChem

影响因子:3.4

doi:10.1002/cmdc.202100473

Ciaffaglione, Valeria; Modica, Maria N; Pittalà, Valeria; Romeo, Giuseppe; Salerno, Loredana; Intagliata, Sebastiano

Semi-Synthetic H(2)S Releasing Compounds with Antioxidant and Vasorelaxant Properties

具有抗氧化和血管舒张特性的半合成H₂S释放化合物

Haloperidol drug repurposing unveils ferroptosis involvement in breast cancer cells.

氟哌啶醇药物再利用揭示了铁死亡在乳腺癌细胞中的作用

Synthesis and in Vitro Evaluation of CAPE Derivatives as Ferroptosis Inducers in Triple Negative Breast Cancer

CAPE衍生物作为三阴性乳腺癌铁死亡诱导剂的合成及体外评价

The Inhibition of Neuropathic Pain Incited by Nerve Injury and Accompanying Mood Disorders by New Heme Oxygenase-1 Inducers: Mechanisms Implicated

新型血红素加氧酶-1诱导剂对神经损伤引起的神经性疼痛及伴随情绪障碍的抑制作用：相关机制

Examination of the Novel Sigma-1 Receptor Antagonist, SI 1/28, for Antinociceptive and Anti-allodynic Efficacy against Multiple Types of Nociception with Fewer Liabilities of Use

对新型Sigma-1受体拮抗剂SI 1/28进行镇痛和抗异位痛疗效研究，以评估其对多种类型伤害性疼痛的疗效和使用风险。

Characterization of CM-398, a Novel Selective Sigma-2 Receptor Ligand, as a Potential Therapeutic for Neuropathic Pain

CM-398（一种新型选择性Sigma-2受体配体）的特性分析及其作为神经性疼痛潜在治疗药物的价值

UPLC-MS/MS method for the quantification of MCI-77, a novel sigma-1 receptor ligand, and its application to pharmacokinetic studies

采用超高效液相色谱-串联质谱法定量分析新型σ-1受体配体MCI-77，并将其应用于药代动力学研究

Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective

Sigma受体配体作为细胞毒性药物的最新进展：药物化学视角

Development of New Benzylpiperazine Derivatives as σ(1) Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects

开发新型苄基哌嗪衍生物作为σ(1)受体配体，并研究其体内镇痛和抗异位痛作用

Mutual Prodrugs of 5-Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs

5-氟尿嘧啶的互惠前药：从经典的化疗药物到新型潜在抗癌药物