Epac activation reduces trans-endothelial migration of undifferentiated neuroblastoma cells and cellular differentiation with a CDK inhibitor further enhances Epac effect.

Epac 激活可减少未分化神经母细胞瘤细胞的跨内皮迁移，而 CDK 抑制剂可进一步增强 Epac 的作用