日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Nanocarriers of shRNA-Runx2 directed to collagen IV as a nanotherapeutic system to target calcific aortic valve disease

shRNA-Runx2 纳米载体针对胶原蛋白 IV,作为治疗钙化性主动脉瓣疾病的纳米治疗系统

Geanina Voicu, Cristina Ana Mocanu, Florentina Safciuc, Maria Anghelache, Mariana Deleanu, Sergiu Cecoltan, Mariana Pinteala, Cristina Mariana Uritu, Ionel Droc, Maya Simionescu, Ileana Manduteanu, Manuela Calin

VCAM-1 Targeted Lipopolyplexes as Vehicles for Efficient Delivery of shRNA-Runx2 to Osteoblast-Differentiated Valvular Interstitial Cells; Implications in Calcific Valve Disease Treatment

VCAM-1 靶向脂质复合物作为将 shRNA-Runx2 有效递送至成骨细胞分化瓣膜间质细胞的载体;对钙化性瓣膜疾病治疗的意义

Geanina Voicu, Daniela Rebleanu, Cristina Ana Mocanu, Gabriela Tanko, Ionel Droc, Cristina Mariana Uritu, Mariana Pinteala, Ileana Manduteanu, Maya Simionescu, Manuela Calin

Parathyroid Hormone Induces Human Valvular Endothelial Cells Dysfunction That Impacts the Osteogenic Phenotype of Valvular Interstitial Cells

甲状旁腺激素诱导人瓣膜内皮细胞功能障碍,进而影响瓣膜间质细胞的成骨表型

Mihaela Vadana ,Sergiu Cecoltan ,Letitia Ciortan ,Razvan D Macarie ,Andreea C Mihaila ,Monica M Tucureanu ,Ana-Maria Gan ,Maya Simionescu ,Ileana Manduteanu ,Ionel Droc ,Elena Butoi

High Glucose Induced Changes in Human VEC Phenotype in a 3D Hydrogel Derived From Cell-Free Native Aortic Root

高葡萄糖诱导的人类 VEC 表型在源自无细胞天然主动脉根部的 3D 水凝胶中发生改变

Sergiu Cecoltan, Letitia Ciortan, Razvan D Macarie, Mihaela Vadana, Andreea C Mihaila, Monica Tucureanu, Mihaela-Loredana Vlad, Ionel Droc, Mihaela Gherghiceanu, Agneta Simionescu, Dan Teodor Simionescu, Elena Butoi, Ileana Manduteanu

Nano-Polyplexes Mediated Transfection of Runx2-shRNA Mitigates the Osteodifferentiation of Human Valvular Interstitial Cells

纳米复合物介导的 Runx2-shRNA 转染减轻了人类瓣膜间质细胞的骨分化

Geanina Voicu, Daniela Rebleanu, Cristina Ana Constantinescu, Elena Valeria Fuior, Letitia Ciortan, Ionel Droc, Cristina Mariana Uritu, Mariana Pinteala, Ileana Manduteanu, Maya Simionescu, Manuela Calin

Molecular mechanisms involved in high glucose-induced valve calcification in a 3D valve model with human valvular cells

人类瓣膜细胞 3D 瓣膜模型中高糖诱导瓣膜钙化的分子机制

Mihaela Vadana, Sergiu Cecoltan, Letitia Ciortan, Razvan D Macarie, Monica M Tucureanu, Andreea C Mihaila, Ionel Droc, Elena Butoi, Ileana Manduteanu

Chronic High Glucose Concentration Induces Inflammatory and Remodeling Changes in Valvular Endothelial Cells and Valvular Interstitial Cells in a Gelatin Methacrylate 3D Model of the Human Aortic Valve

慢性高血糖浓度诱导人主动脉瓣明胶甲基丙烯酸酯 3D 模型中的瓣膜内皮细胞和瓣膜间质细胞发生炎症和重塑变化

Letitia Ciortan, Razvan Daniel Macarie, Sergiu Cecoltan, Mihaela Vadana, Monica Madalina Tucureanu, Andreea Cristina Mihaila, Ionel Droc, Elena Butoi, Ileana Manduteanu