日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Extracellular vesicles from the lung pro-thrombotic niche drive cancer-associated thrombosis and metastasis via integrin beta 2

肺促血栓形成微环境产生的细胞外囊泡通过整合素β2驱动癌症相关血栓形成和转移

Serena Lucotti,Yusuke Ogitani,Candia M Kenific,Jacob Geri,Young Hun Kim,Jinghua Gu,Uthra Balaji,Linda Bojmar,Lee Shaashua,Yi Song,Michele Cioffi,Pernille Lauritzen,Oveen M Joseph,Tetsuhiko Asao,Paul M Grandgenett,Michael A Hollingsworth,Christopher Peralta,Alexandra E Pagano,Henrik Molina,Harry B Lengel,Elizabeth G Dunne,Xiaohong Jing,Madeleine Schmitter,Lucia Borriello,Thomas Miller,Haiying Zhang,Yevgeniy Romin,Katia Manova,Doru Paul,H Lawrence Remmel,Eileen M O'Reilly,William R Jarnagin,David Kelsen,Sharon M Castellino,Lisa Giulino-Roth,David R Jones,John S Condeelis,Virginia Pascual,James B Bussel,Nancy Boudreau,Irina Matei,David Entenberg,Jacqueline F Bromberg,Diane M Simeone,David Lyden

Extracellular vesicles from the lung pro-thrombotic niche drive cancer-associated thrombosis and metastasis via integrin beta 2

肺促血栓形成微环境产生的细胞外囊泡通过整合素β2驱动癌症相关血栓形成和转移

Serena Lucotti ,Yusuke Ogitani ,Candia M Kenific ,Jacob Geri ,Young Hun Kim ,Jinghua Gu ,Uthra Balaji ,Linda Bojmar ,Lee Shaashua ,Yi Song ,Michele Cioffi ,Pernille Lauritzen ,Oveen M Joseph ,Tetsuhiko Asao ,Paul M Grandgenett ,Michael A Hollingsworth ,Christopher Peralta ,Alexandra E Pagano ,Henrik Molina ,Harry B Lengel ,Elizabeth G Dunne ,Xiaohong Jing ,Madeleine Schmitter ,Lucia Borriello ,Thomas Miller ,Haiying Zhang ,Yevgeniy Romin ,Katia Manova ,Doru Paul ,H Lawrence Remmel ,Eileen M O'Reilly ,William R Jarnagin ,David Kelsen ,Sharon M Castellino ,Lisa Giulino-Roth ,David R Jones ,John S Condeelis ,Virginia Pascual ,James B Bussel ,Nancy Boudreau ,Irina Matei ,David Entenberg ,Jacqueline F Bromberg ,Diane M Simeone ,David Lyden

Unique structural configuration of EV-DNA primes Kupffer cell-mediated antitumor immunity to prevent metastatic progression

EV-DNA独特的结构构型可启动库普弗细胞介导的抗肿瘤免疫,从而阻止转移进展。

Inbal Wortzel,Yura Seo #,Ife Akano #,Lee Shaashua,Gabriel Cardial Tobias,Jakob Hebert,Kyung-A Kim,DooA Kim,Shani Dror,Yanshen Liu,Griffin Campbell Azrak,Michele Cioffi,Kofi Ennu Johnson,Tammy Hennika,Meshulam Zisha Twerski,Alexis Kushner,Robert Math,Yoon Dae Han,Dai Hoon Han,Minsun Jung,Juyeong Park,Soonmyung Paik,Jeon-Soo Shin,Min Goo Lee,Marco Vincenzo Russo,Daniel Zakheim,Jesse Barnes,Sunjoy Mehta,Katia Manova,Robert E Schwartz,Basant Kumar Thakur,Nancy Boudreau,Irina Matei,Haiying Zhang,Simone Sidoli,Jacqueline Bromberg,Yael David,Han Sang Kim,David Lyden

Unique structural configuration of EV-DNA primes Kupffer cell-mediated antitumor immunity to prevent metastatic progression

EV-DNA独特的结构构型可启动库普弗细胞介导的抗肿瘤免疫,从而阻止转移进展。

Inbal Wortzel ,Yura Seo # ,Ife Akano # ,Lee Shaashua ,Gabriel Cardial Tobias ,Jakob Hebert ,Kyung-A Kim ,DooA Kim ,Shani Dror ,Yanshen Liu ,Griffin Campbell Azrak ,Michele Cioffi ,Kofi Ennu Johnson ,Tammy Hennika ,Meshulam Zisha Twerski ,Alexis Kushner ,Robert Math ,Yoon Dae Han ,Dai Hoon Han ,Minsun Jung ,Juyeong Park ,Soonmyung Paik ,Jeon-Soo Shin ,Min Goo Lee ,Marco Vincenzo Russo ,Daniel Zakheim ,Jesse Barnes ,Sunjoy Mehta ,Katia Manova ,Robert E Schwartz ,Basant Kumar Thakur ,Nancy Boudreau ,Irina Matei ,Haiying Zhang ,Simone Sidoli ,Jacqueline Bromberg ,Yael David ,Han Sang Kim ,David Lyden

MAP kinase kinase 1 (MEK1) within extracellular vesicles inhibits tumour growth by promoting anti-tumour immunity

细胞外囊泡内的 MAP 激酶激酶 1 (MEK1) 通过促进抗肿瘤免疫来抑制肿瘤生长

Stephen C Searles, Wei-Shan Chen, Jarrod D Yee, Preston Lee, Calvin K Lee, Christine Caron, Felippe Neto, Irina Matei, David Lyden, Jack D Bui

Spatiotemporal expression and control of haemoglobin in space

空间中血红蛋白的时空表达和控制

Josef Borg # ,Conor Loy # ,JangKeun Kim # ,Alfred Buhagiar ,Christopher Chin ,Namita Damle ,Iwijn De Vlaminck ,Alex Felice ,Tammy Liu ,Irina Matei ,Cem Meydan ,Masafumi Muratani ,Omary Mzava ,Eliah Overbey ,Krista A Ryon ,Scott M Smith ,Braden T Tierney ,Guy Trudel ,Sara R Zwart ,Afshin Beheshti ,Christopher E Mason ,Joseph Borg

Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight

“灵感4号”宇航员的单细胞多组学和免疫谱分析揭示了太空飞行中保守的、细胞类型特异性和性别特异性的反应

JangKeun Kim # ,Braden T Tierney # ,Eliah G Overbey ,Ezequiel Dantas ,Matias Fuentealba ,Jiwoon Park ,S Anand Narayanan ,Fei Wu ,Deena Najjar ,Christopher R Chin ,Cem Meydan ,Conor Loy ,Begum Mathyk ,Remi Klotz ,Veronica Ortiz ,Khiem Nguyen ,Krista A Ryon ,Namita Damle ,Nadia Houerbi ,Laura I Patras ,Nathan Schanzer ,Gwyneth A Hutchinson ,Jonathan Foox ,Chandrima Bhattacharya ,Matthew Mackay ,Evan E Afshin ,Jeremy Wain Hirschberg ,Ashley S Kleinman ,Julian C Schmidt ,Caleb M Schmidt ,Michael A Schmidt ,Afshin Beheshti ,Irina Matei ,David Lyden ,Sean Mullane ,Amran Asadi ,Joan S Lenz ,Omary Mzava ,Min Yu ,Saravanan Ganesan ,Iwijn De Vlaminck ,Ari M Melnick ,Darko Barisic ,Daniel A Winer ,Sara R Zwart ,Brian E Crucian ,Scott M Smith ,Jaime Mateus ,David Furman ,Christopher E Mason

Collection of biospecimens from the inspiration4 mission establishes the standards for the space omics and medical atlas (SOMA)

inspiration4 任务收集的生物样本为空间组学和医学图谱 (SOMA) 制定了标准

Eliah G Overbey, Krista Ryon, JangKeun Kim, Braden T Tierney, Remi Klotz, Veronica Ortiz, Sean Mullane, Julian C Schmidt, Matthew MacKay, Namita Damle, Deena Najjar, Irina Matei, Laura Patras, J Sebastian Garcia Medina, Ashley S Kleinman, Jeremy Wain Hirschberg, Jacqueline Proszynski, S Anand Naraya

Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight

“灵感4号”宇航员的单细胞多组学和免疫谱分析揭示了太空飞行中保守的、细胞类型特异性和性别特异性的反应

JangKeun Kim #,Braden T Tierney #,Eliah G Overbey ,Ezequiel Dantas,Matias Fuentealba,Jiwoon Park,S Anand Narayanan,Fei Wu,Deena Najjar,Christopher R Chin,Cem Meydan ,Conor Loy,Begum Mathyk,Remi Klotz,Veronica Ortiz,Khiem Nguyen,Krista A Ryon,Namita Damle,Nadia Houerbi,Laura I Patras,Nathan Schanzer,Gwyneth A Hutchinson ,Jonathan Foox,Chandrima Bhattacharya,Matthew Mackay,Evan E Afshin,Jeremy Wain Hirschberg,Ashley S Kleinman,Julian C Schmidt,Caleb M Schmidt ,Michael A Schmidt,Afshin Beheshti,Irina Matei,David Lyden,Sean Mullane,Amran Asadi,Joan S Lenz,Omary Mzava,Min Yu,Saravanan Ganesan,Iwijn De Vlaminck,Ari M Melnick,Darko Barisic,Daniel A Winer ,Sara R Zwart,Brian E Crucian,Scott M Smith,Jaime Mateus,David Furman ,Christopher E Mason

Role of the afferent lymph as an immunological conduit to analyze tissue antigenic and inflammatory load

传入淋巴作为免疫通道在分析组织抗原和炎症负荷中的作用

Padma P Nanaware ,Zohaib N Khan ,Cristina C Clement ,Madhur Shetty ,Ines Mota ,Ethan S Seltzer ,Monika Dzieciatkowska ,Fabia Gamboni ,Angelo D'Alessandro ,Charles Ng ,Manabu Nagayama ,Cheryl F Lichti ,Rajesh K Soni ,Jacob B Geri ,Irina Matei ,David Lyden ,Randy Longman ,Theresa T Lu ,Xiaoxiao Wan ,Emil R Unanue ,Lawrence J Stern ,Laura Santambrogio