日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
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2026
影响因子:
–

Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors

针对含GluN2C/2D亚型的NMDA受体的亚型选择性竞争性拮抗作用的结构基础

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-020-14321-0
Wang, Jue Xiang; Irvine, Mark W; Burnell, Erica S; Sapkota, Kiran; Thatcher, Robert J; Li, Minjun; Simorowski, Noriko; Volianskis, Arturas; Collingridge, Graham L; Monaghan, Daniel T; Jane, David E; Furukawa, Hiro
信号转导
发表日期：2020
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Investigation of the structural requirements for N-methyl-D-aspartate receptor positive and negative allosteric modulators based on 2-naphthoic acid

基于2-萘甲酸的N-甲基-D-天冬氨酸受体正负变构调节剂的结构要求研究

期刊:European Journal of Medicinal Chemistry
影响因子:5.9
doi:10.1016/j.ejmech.2018.12.054
Irvine, Mark W; Fang, Guangyu; Sapkota, Kiran; Burnell, Erica S; Volianskis, Arturas; Costa, Blaise M; Culley, Georgia; Collingridge, Graham L; Monaghan, Daniel T; Jane, David E
信号转导
发表日期：2019
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The Startle Disease Mutation E103K Impairs Activation of Human Homomeric α1 Glycine Receptors by Disrupting an Intersubunit Salt Bridge across the Agonist Binding Site

惊吓病突变 E103K 通过破坏激动剂结合位点上的亚基间盐桥，损害人同源 α1 甘氨酸受体的激活。

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.M116.767616
Safar, Fatemah; Hurdiss, Elliot; Erotocritou, Marios; Greiner, Timo; Lape, Remigijus; Irvine, Mark W; Fang, Guangyu; Jane, David; Yu, Rilei; Dämgen, Marc A; Biggin, Philip C; Sivilotti, Lucia G
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Human
发表日期：2017
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The NMDA receptor as a target for cognitive enhancement.

NMDA受体作为认知增强的靶点

期刊:Neuropharmacology
影响因子:4.6
doi:10.1016/j.neuropharm.2012.06.051
Collingridge Graham L, Volianskis Arturas, Bannister Neil, France Grace, Hanna Lydia, Mercier Marion, Tidball Patrick, Fang Guangyu, Irvine Mark W, Costa Blaise M, Monaghan Daniel T, Bortolotto Zuner A, Molnár Elek, Lodge David, Jane David E
神经科学
信号转导
发表日期：2013
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Piperazine-2,3-dicarboxylic acid derivatives as dual antagonists of NMDA and GluK1-containing kainate receptors

哌嗪-2,3-二羧酸衍生物作为NMDA和含GluK1的红藻氨酸受体的双重拮抗剂

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/jm201230z
Irvine, Mark W; Costa, Blaise M; Dlaboga, Daniel; Culley, Georgia R; Hulse, Richard; Scholefield, Caroline L; Atlason, Palmi; Fang, Guangyu; Eaves, Richard; Morley, Richard; Mayo-Martin, Maria B; Amici, Mascia; Bortolotto, Zuner A; Donaldson, Lucy; Collingridge, Graham L; Molnár, Elek; Monaghan, Daniel T; Jane, David E
信号转导
发表日期：2012
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Structure-activity relationships for allosteric NMDA receptor inhibitors based on 2-naphthoic acid

基于2-萘甲酸的变构NMDA受体抑制剂的构效关系

期刊:Neuropharmacology
影响因子:4.6
doi:10.1016/j.neuropharm.2011.11.019
Costa, Blaise Mathias; Irvine, Mark W; Fang, Guangyu; Eaves, Richard J; Mayo-Martin, Maria Belen; Laube, Bodo; Jane, David E; Monaghan, Daniel T
信号转导
发表日期：2012
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Coumarin-3-carboxylic acid derivatives as potentiators and inhibitors of recombinant and native N-methyl-D-aspartate receptors

香豆素-3-羧酸衍生物作为重组和天然N-甲基-D-天冬氨酸受体的增强剂和抑制剂

期刊:Neurochemistry International
影响因子:4
doi:10.1016/j.neuint.2011.12.020
Irvine, Mark W; Costa, Blaise M; Volianskis, Arturas; Fang, Guangyu; Ceolin, Laura; Collingridge, Graham L; Monaghan, Daniel T; Jane, David E
信号转导
发表日期：2012
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Pharmacological modulation of NMDA receptor activity and the advent of negative and positive allosteric modulators

NMDA受体活性的药理学调节以及负变构调节剂和正变构调节剂的出现

期刊:Neurochemistry International
影响因子:4
doi:10.1016/j.neuint.2012.01.004
Monaghan, Daniel T; Irvine, Mark W; Costa, Blaise Mathias; Fang, Guangyu; Jane, David E
信号转导
发表日期：2012
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A novel family of negative and positive allosteric modulators of NMDA receptors

一种新型的NMDA受体正负变构调节剂家族

期刊:Journal of Pharmacology and Experimental Therapeutics
影响因子:3.8
doi:10.1124/jpet.110.174144
Costa, Blaise Mathias; Irvine, Mark W; Fang, Guangyu; Eaves, Richard J; Mayo-Martin, Marie Belen; Skifter, Donald A; Jane, David E; Monaghan, Daniel T
信号转导
发表日期：2010
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N-methyl-D-aspartate (NMDA) receptor NR2 subunit selectivity of a series of novel piperazine-2,3-dicarboxylate derivatives: preferential blockade of extrasynaptic NMDA receptors in the rat hippocampal CA3-CA1 synapse

一系列新型哌嗪-2,3-二羧酸衍生物对N-甲基-D-天冬氨酸（NMDA）受体NR2亚基的选择性：优先阻断大鼠海马CA3-CA1突触外NMDA受体

期刊:Journal of Pharmacology and Experimental Therapeutics
影响因子:3.8
doi:10.1124/jpet.109.156752
Costa, Blaise Mathias; Feng, Bihua; Tsintsadze, Timur S; Morley, Richard M; Irvine, Mark W; Tsintsadze, Vera; Lozovaya, Natasha A; Jane, David E; Monaghan, Daniel T
信号转导
Rat
神经科学
发表日期：2009
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