日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Single-Cell Transcriptomics Identifies a Prominent Role for the MIF-CD74 Axis in Myasthenia Gravis Thymus

单细胞转录组学揭示MIF-CD74轴在重症肌无力胸腺中的重要作用

Paula Terroba-Navajas ,I-Na Lu ,Isaak Quast ,Michael Heming ,Christian W Keller ,Lennard Ostendorf ,Anja Erika Hauser ,Ronja Mothes ,Helena Radbruch ,Frauke Stascheit ,Andreas Georg Otto Meisel ,Heinz Wiendl ,Gerd Meyer Zu Hörste ,Nick Willcox ,Jan D Lünemann

Syndecans and glycosaminoglycans influence B-cell development and activation

聚糖和糖胺聚糖影响B细胞的发育和活化。

Craig I McKenzie,Alexandra R Dvorscek,Zhoujie Ding,Marcus J Robinson,Kristy O'Donnell,Catherine Pitt,Daniel T Ferguson,Jesse Mulder,Marco J Herold,David M Tarlinton,Isaak Quast

Ki67 deficiency impedes chromatin accessibility and BCR gene rearrangement

Ki67 缺乏阻碍染色质的可及性和 BCR 基因重排

Zhoujie Ding #, Maree Hagan #, Feng Yan, Nick W Y Schroer, Jack Polmear, Kim L Good-Jacobson, Alexandra R Dvorscek, Catherine Pitt, Kristy O'Donnell, Stephen L Nutt, Dimitra Zotos, Craig McKenzie, Danika L Hill, Marcus J Robinson, Isaak Quast, Frank Koentgen #, David M Tarlinton #

Intrinsically determined turnover underlies broad heterogeneity in plasma-cell lifespan

内在决定的周转是浆细胞寿命广泛异质性的基础

Marcus James Robinson, Zhoujie Ding, Mark R Dowling, Danika L Hill, Rosela H Webster, Craig McKenzie, Catherine Pitt, Kristy O'Donnell, Jesse Mulder, Erica Brodie, Philip D Hodgkin, Nick C Wong, Isaak Quast, David M Tarlinton

IL-21 has a critical role in establishing germinal centers by amplifying early B cell proliferation

IL-21通过促进早期B细胞增殖在生发中心的建立中起着关键作用。

Alexandra R Dvorscek ,Craig I McKenzie ,Marcus J Robinson ,Zhoujie Ding ,Catherine Pitt ,Kristy O'Donnell ,Dimitra Zotos ,Robert Brink ,David M Tarlinton ,Isaak Quast

CD137L and CD4 T cells limit BCL6-expressing pre-germinal center B cell expansion and BCL6-driven B cell malignancy

CD137L 和 CD4 T 细胞限制表达 BCL6 的前生发中心 B 细胞扩增和 BCL6 驱动的 B 细胞恶性肿瘤

Zhoujie Ding, Isaak Quast, Feng Yan, Yang Liao, Catherine Pitt, Kristy O-Donnell, Marcus J Robinson, Wei Shi, Axel Kallies, Dimitra Zotos, David M Tarlinton

The concerted change in the distribution of cell cycle phases and zone composition in germinal centers is regulated by IL-21

IL-21 调控生发中心细胞周期各阶段分布和区域组成的协同变化

Dimitra Zotos # ,Isaak Quast # ,Connie S N Li-Wai-Suen ,Craig I McKenzie ,Marcus J Robinson ,Andrey Kan ,Gordon K Smyth ,Philip D Hodgkin ,David M Tarlinton

EBV renders B cells susceptible to HIV-1 in humanized mice

在人源化小鼠中,EBV使B细胞易受HIV-1感染。

Donal McHugh ,Renier Myburgh ,Nicole Caduff ,Michael Spohn ,Yik Lim Kok ,Christian W Keller ,Anita Murer ,Bithi Chatterjee ,Julia Rühl ,Christine Engelmann ,Obinna Chijioke ,Isaak Quast ,Mohaned Shilaih ,Victoria P Strouvelle ,Kathrin Neumann ,Thomas Menter ,Stephan Dirnhofer ,Janice Kp Lam ,Kwai F Hui ,Simon Bredl ,Erika Schlaepfer ,Silvia Sorce ,Andrea Zbinden ,Riccarda Capaul ,Jan D Lünemann ,Adriano Aguzzi ,Alan Ks Chiang ,Werner Kempf ,Alexandra Trkola ,Karin J Metzner ,Markus G Manz ,Adam Grundhoff ,Roberto F Speck ,Christian Münz

The autophagy machinery restrains iNKT cell activation through CD1D1 internalization

自噬机制通过 CD1D1 内吞作用抑制 iNKT 细胞活化。

Christian W Keller ,Monica Loi ,Svenja Ewert ,Isaak Quast ,Romina Theiler ,Monique Gannagé ,Christian Münz ,Gennaro De Libero ,Stefan Freigang ,Jan D Lünemann

Fc-Galactosylation of Human Immunoglobulin Gamma Isotypes Improves C1q Binding and Enhances Complement-Dependent Cytotoxicity

人免疫球蛋白γ亚型的Fc-半乳糖基化可改善C1q结合并增强补体依赖性细胞毒性

Benjamin Peschke ,Christian W Keller ,Patrick Weber ,Isaak Quast ,Jan D Lünemann