日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Host-parasite co-metabolic activation of antitrypanosomal aminomethyl-benzoxaboroles

抗锥虫氨甲基苯并氧硼酸的宿主-寄生虫共代谢激活

Ning Zhang, Martin Zoltner, Ka-Fai Leung, Paul Scullion, Sebastian Hutchinson, Ricardo C Del Pino, Isabel M Vincent, Yong-Kang Zhang, Yvonne R Freund, Michael R K Alley, Robert T Jacobs, Kevin D Read, Michael P Barrett, David Horn, Mark C Field

The trypanocidal benzoxaborole AN7973 inhibits trypanosome mRNA processing

杀锥虫剂苯并氧硼酸 AN7973 可抑制锥虫 mRNA 加工

Daniela Begolo, Isabel M Vincent, Federica Giordani, Ina Pöhner, Michael J Witty, Timothy G Rowan, Zakaria Bengaly, Kirsten Gillingwater, Yvonne Freund, Rebecca C Wade, Michael P Barrett, Christine Clayton

Sterol 14α-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana

甾醇 14α-脱甲基酶突变导致墨西哥利什曼原虫对两性霉素 B 产生耐药性

Roy Mwenechanya, Julie Kovářová, Nicholas J Dickens, Manikhandan Mudaliar, Pawel Herzyk, Isabel M Vincent, Stefan K Weidt, Karl E Burgess, Richard J S Burchmore, Andrew W Pountain, Terry K Smith, Darren J Creek, Dong-Hyun Kim, Galina I Lepesheva, Michael P Barrett

Different Mutations in a P-type ATPase Transporter in Leishmania Parasites are Associated with Cross-resistance to Two Leading Drugs by Distinct Mechanisms

利什曼原虫 P 型 ATPase 转运蛋白的不同突变通过不同的机制与对两种主要药物的交叉耐药性相关

Christopher Fernandez-Prada, Isabel M Vincent, Marie-Christine Brotherton, Mathew Roberts, Gaétan Roy, Luis Rivas, Philippe Leprohon, Terry K Smith, Marc Ouellette

Untargeted metabolomic analysis of miltefosine action in Leishmania infantum reveals changes to the internal lipid metabolism

对婴儿利什曼原虫米替福新作用的非靶向代谢组学分析揭示了内部脂质代谢的变化

Isabel M Vincent, Stefan Weidt, Luis Rivas, Karl Burgess, Terry K Smith, Marc Ouellette

Untargeted metabolomics reveals a lack of synergy between nifurtimox and eflornithine against Trypanosoma brucei

非靶向代谢组学揭示硝呋噻氧和依氟鸟氨酸对布氏锥虫缺乏协同作用

Isabel M Vincent, Darren J Creek, Karl Burgess, Debra J Woods, Richard J S Burchmore, Michael P Barrett