日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Serum proteomic and metabolomic analyses from patients with IBD identify biological pathways associated with treatment success with anti-integrin therapy

对IBD患者血清蛋白质组学和代谢组学分析揭示了与抗整合素治疗成功相关的生物学通路

Rioux, John D; Boucher, Gabrielle; Forest, Anik; Bouchard, Bertrand; Coderre, Lise; Daneault, Caroline; Frayne, Isabelle Robillard; Legault, Julie Thompson; Bitton, Alain; Ananthakrishnan, Ashwin; Lesage, Sylvie; Xavier, Ramnik J; Des Rosiers, Christine

PCSK7: A novel regulator of apolipoprotein B and a potential target against non-alcoholic fatty liver disease

PCSK7:载脂蛋白 B 的新型调节剂和非酒精性脂肪肝的潜在靶点

Vatsal Sachan, Maïlys Le Dévéhat, Anna Roubtsova, Rachid Essalmani, Jean-Francois Laurendeau, Damien Garçon, Delia Susan-Resiga, Stéphanie Duval, Sahar Mikaeeli, Josée Hamelin, Alexandra Evagelidis, Michael Chong, Guillaume Paré, Elizabeta Chernetsova, Zu-Hua Gao, Isabelle Robillard, Matthieu Ruiz, 

A pilot study to identify blood-based markers associated with response to treatment with Vedolizumab in patients with Inflammatory Bowel Disease

一项旨在识别与炎症性肠病患者接受维多珠单抗治疗反应相关的血液标志物的试点研究

Rioux, John D; Boucher, Gabrielle; Forest, Anik; Bouchard, Bertrand; Coderre, Lise; Daneault, Caroline; Frayne, Isabelle Robillard; Legault, Julie Thompson; Bitton, Alain; Ananthakrishnan, Ashwin; Lesage, Sylvie; Xavier, Ramnik J; Des Rosiers, Christine

Depletion of LONP2 unmasks differential requirements for peroxisomal function between cell types and in cholesterol metabolism

LONP2 的缺失揭示了不同细胞类型和胆固醇代谢中过氧化物酶体功能的不同需求

Akihiro Yamashita, Olesia Ignatenko, Mai Nguyen, Raphaëlle Lambert, Kathleen Watt, Caroline Daneault, Isabelle Robillard-Frayne, Ivan Topisirovic, Christine Des Rosiers, Heidi M McBride

Very-Long-Chain Unsaturated Sphingolipids Mediate Oleate-Induced Rat β-Cell Proliferation

超长链不饱和鞘脂介导油酸诱导的大鼠β细胞增殖

Castell, Anne-Laure; Vivoli, Alexis; Tippetts, Trevor S; Frayne, Isabelle Robillard; Angeles, Zuraya Elisa; Moullé, Valentine S; Campbell, Scott A; Ruiz, Matthieu; Ghislain, Julien; Des Rosiers, Christine; Holland, William L; Summers, Scott A; Poitout, Vincent

Branched chain amino acids selectively promote cardiac growth at the end of the awake period

支链氨基酸选择性地促进清醒期末期的心脏生长

Mary N Latimer, Ravi Sonkar, Sobuj Mia, Isabelle Robillard Frayne, Karen J Carter, Christopher A Johnson, Samir Rana, Min Xie, Glenn C Rowe, Adam R Wende, Sumanth D Prabhu, Stuart J Frank, Christine Des Rosiers, John C Chatham, Martin E Young

Mitochondrial pyruvate carriers are required for myocardial stress adaptation

线粒体丙酮酸载体是心肌应激适应所必需的

Yuan Zhang, Paul V Taufalele, Jesse D Cochran, Isabelle Robillard-Frayne, Jonas Maximilian Marx, Jamie Soto, Adam J Rauckhorst, Fariba Tayyari, Alvin D Pewa, Lawrence R Gray, Lynn M Teesch, Patrycja Puchalska, Trevor R Funari, Rose McGlauflin, Kathy Zimmerman, William J Kutschke, Thomas Cassier, Sha

Reducing 14-3-3ζ expression influences adipocyte maturity and impairs function

降低 14-3-3ζ 表达会影响脂肪细胞成熟并损害功能

Abel K Oppong, Kadidia Diallo, Isabelle Robillard Frayne, Christine Des Rosiers, Gareth E Lim

Lipidomics unveils lipid dyshomeostasis and low circulating plasmalogens as biomarkers in a monogenic mitochondrial disorder

脂质组学揭示脂质失衡和低循环缩醛磷脂是单基因线粒体疾病的生物标志物

Matthieu Ruiz, Alexanne Cuillerier, Caroline Daneault, Sonia Deschênes, Isabelle Robillard Frayne, Bertrand Bouchard, Anik Forest, Julie Thompson Legault; LSFC Consortium; Frederic M Vaz, John D Rioux, Yan Burelle, Christine Des Rosiers

Comprehensive and Reproducible Untargeted Lipidomic Workflow Using LC-QTOF Validated for Human Plasma Analysis

经验证可用于人体血浆分析的全面且可重复的非靶向脂质组学工作流程(使用 LC-QTOF)

Anik Forest, Matthieu Ruiz, Bertrand Bouchard, Gabrielle Boucher, Olivier Gingras, Caroline Daneault, Isabelle Robillard Frayne, David Rhainds; iGenoMed Consortium; NIDDK IBD Genetics Consortium; Jean-Claude Tardif, John D Rioux, Christine Des Rosiers