日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Aberrant splicing in neuroblastoma generates RNA-fusion transcripts and provides vulnerability to spliceosome inhibitors

神经母细胞瘤中的异常剪接产生 RNA 融合转录本,并导致其易受剪接体抑制剂的攻击

Yao Shi, Juan Yuan, Vilma Rraklli, Eva Maxymovitz, Miriam Cipullo, Mingzhi Liu, Shuijie Li, Isabelle Westerlund, Oscar C Bedoya-Reina, Petra Bullova, Joanna Rorbach, C Christofer Juhlin, Adam Stenman, Catharina Larsson, Per Kogner, Maureen J O'Sullivan, Susanne Schlisio, Johan Holmberg

EPAS1/HIF2α correlates with features of low-risk neuroblastoma and with adrenal chromaffin cell differentiation during sympathoadrenal development

EPAS1/HIF2α 与低风险神经母细胞瘤的特征以及交感肾上腺发育过程中的肾上腺嗜铬细胞分化相关

Isabelle Westerlund, Yao Shi, Johan Holmberg

EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance

EglN3 羟化酶稳定 BIM-EL,将 VHL 2C 型突变与嗜铬细胞瘤发病机制和化疗耐药性联系起来

Shuijie Li, Javier Rodriguez, Wenyu Li, Petra Bullova, Stuart M Fell, Olga Surova, Isabelle Westerlund, Danijal Topcic, Maria Bergsland, Adam Stenman, Jonas Muhr, Monica Nistér, Johan Holmberg, C Christofer Juhlin, Catharina Larsson, Alex von Kriegsheim, William G Kaelin Jr, Susanne Schlisio

Combined epigenetic and differentiation-based treatment inhibits neuroblastoma tumor growth and links HIF2α to tumor suppression

表观遗传和分化联合治疗可抑制神经母细胞瘤肿瘤生长,并将 HIF2α 与肿瘤抑制联系起来

Isabelle Westerlund, Yao Shi, Konstantinos Toskas, Stuart M Fell, Shuijie Li, Olga Surova, Erik Södersten, Per Kogner, Ulrika Nyman, Susanne Schlisio, Johan Holmberg