Isacson Ole相关文献与解析，生知库 | 链接生命科学的每一步

ApoE4 requires lipidation enhancement to resolve cellular lipid and protein abnormalities following NPC1 inhibition.

ApoE4 需要脂化增强来解决 NPC1 抑制后细胞脂质和蛋白质异常

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-025-96531-4

Di Biase Erika, Connolly Kyle J, Crumpton Ingrid, Cooper Oliver, Hallett Penelope J, Isacson Ole

细胞生物学

发表日期：2025

文献求助收藏

APOE3 astrocytes can rescue lipid abnormalities and dystrophic neurites of APOE4 human neurons

APOE3星形胶质细胞可以挽救APOE4人类神经元的脂质异常和营养不良性神经突。

期刊:

影响因子:

doi:10.1101/2025.10.24.684364

Halim, Dilara O; Di Biase, Erika; Rajon, Amélie; Jordi, Luc; Hallett, Penelope J; Isacson, Ole

Neuronal threshold functions: Determining symptom onset in neurological disorders

神经元阈值功能：确定神经系统疾病的症状发作

期刊:Progress in Neurobiology

影响因子:6.1

doi:10.1016/j.pneurobio.2024.102673

Jordi, Luc; Isacson, Ole

神经科学

发表日期：2024

文献求助收藏

Upstream lipid and metabolic systems are potential causes of Alzheimer's disease, Parkinson's disease and dementias

上游脂质和代谢系统是阿尔茨海默病、帕金森病和痴呆症的潜在病因。

期刊:

影响因子:

doi:10.1111/febs.16638

Cooper, Oliver; Hallett, Penny; Isacson, Ole

Advantages and Recent Developments of Autologous Cell Therapy for Parkinson's Disease Patients

自体细胞疗法治疗帕金森病患者的优势及最新进展

期刊:Frontiers in Cellular Neuroscience

影响因子:4

doi:10.3389/fncel.2020.00058

Osborn, Teresia M; Hallett, Penelope J; Schumacher, James M; Isacson, Ole

Lipid and immune abnormalities causing age-dependent neurodegeneration and Parkinson's disease

脂质和免疫异常导致与年龄相关的神经退行性变和帕金森病

期刊:Journal of Neuroinflammation

影响因子:10.1

doi:10.1186/s12974-019-1532-2

Hallett, Penelope J; Engelender, Simone; Isacson, Ole

Comprehensive Cell Surface Antigen Analysis Identifies Transferrin Receptor Protein-1 (CD71) as a Negative Selection Marker for Human Neuronal Cells

全面的细胞表面抗原分析鉴定出转铁蛋白受体蛋白-1 (CD71) 为人类神经元细胞的阴性选择标志物

期刊:Stem Cells

影响因子:3.6

doi:10.1002/stem.3057

Menon, Vishal; Thomas, Ria; Elgueta, Claudio; Horl, Marcus; Osborn, Teresia; Hallett, Penny J; Bartos, Marlene; Isacson, Ole; Pruszak, Jan

Novel Results and Concepts Emerging From Lipid Cell Biology Relevant to Degenerative Brain Aging and Disease

脂质细胞生物学领域涌现出的新成果和新概念与脑退行性衰老和疾病相关

期刊:Frontiers in Neurology

影响因子:2.8

doi:10.3389/fneur.2019.01053

Isacson, Ole; Brekk, Oeystein R; Hallett, Penelope J

Successful function of autologous iPSC-derived dopamine neurons following transplantation in a non-human primate model of Parkinson's disease

自体iPSC衍生的多巴胺神经元移植到帕金森病非人灵长类动物模型后成功发挥功能

期刊:Cell Stem Cell

影响因子:20.4

doi:10.1016/j.stem.2015.01.018

Hallett, Penelope J; Deleidi, Michela; Astradsson, Arnar; Smith, Gaynor A; Cooper, Oliver; Osborn, Teresia M; Sundberg, Maria; Moore, Michele A; Perez-Torres, Eduardo; Brownell, Anna-Liisa; Schumacher, James M; Spealman, Roger D; Isacson, Ole

APOE3 astrocytes can rescue lipid abnormalities and dystrophic neurites of APOE4 human neurons.

APOE3 星形胶质细胞可以挽救 APOE4 人类神经元的脂质异常和营养不良性神经突。

ApoE4 requires lipidation enhancement to resolve cellular lipid and protein abnormalities following NPC1 inhibition.

ApoE4 需要脂化增强来解决 NPC1 抑制后细胞脂质和蛋白质异常

APOE3 astrocytes can rescue lipid abnormalities and dystrophic neurites of APOE4 human neurons

APOE3星形胶质细胞可以挽救APOE4人类神经元的脂质异常和营养不良性神经突。

Neuronal threshold functions: Determining symptom onset in neurological disorders

神经元阈值功能：确定神经系统疾病的症状发作

Upstream lipid and metabolic systems are potential causes of Alzheimer's disease, Parkinson's disease and dementias

上游脂质和代谢系统是阿尔茨海默病、帕金森病和痴呆症的潜在病因。

Advantages and Recent Developments of Autologous Cell Therapy for Parkinson's Disease Patients

自体细胞疗法治疗帕金森病患者的优势及最新进展

Lipid and immune abnormalities causing age-dependent neurodegeneration and Parkinson's disease

脂质和免疫异常导致与年龄相关的神经退行性变和帕金森病

Comprehensive Cell Surface Antigen Analysis Identifies Transferrin Receptor Protein-1 (CD71) as a Negative Selection Marker for Human Neuronal Cells

全面的细胞表面抗原分析鉴定出转铁蛋白受体蛋白-1 (CD71) 为人类神经元细胞的阴性选择标志物

Novel Results and Concepts Emerging From Lipid Cell Biology Relevant to Degenerative Brain Aging and Disease

脂质细胞生物学领域涌现出的新成果和新概念与脑退行性衰老和疾病相关

Successful function of autologous iPSC-derived dopamine neurons following transplantation in a non-human primate model of Parkinson's disease

自体iPSC衍生的多巴胺神经元移植到帕金森病非人灵长类动物模型后成功发挥功能