日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Type I and III interferons synergize with TNF to promote virally-triggered damage to the intestinal epithelium

I型和III型干扰素与TNF协同作用,促进病毒引发的肠道上皮损伤。

Bernard-Raichon, Lucie; Neil, Jessica A; Kim, Kayla; Heaney, Thomas; Miller, Brittany M; Moon, Damee; Lubkin, Ashira; DuMont, Ashley L; Torres, Victor J; Axelrad, Jordan; Matsuzawa-Ishimoto, Yu; Cadwell, Ken

Studies of mice with a large deletion of the ARPKD-associated Pkhd1 locus likely explain its GWAS association with glaucoma in humans.

对 ARPKD 相关基因 Pkhd1 位点大片段缺失的小鼠的研究可能解释了其 GWAS 与人类青光眼的关联。

Ishimoto Yu, Menezes Luis F, Nakaya Naoki, Barbosa Karla, Horie Yukihiro, Yoshida Teruhiko, Reece Jeff, Zhou Fang, Tomarev Stanislav, Kerosuo Laura, Germino Gregory G

Single-Nucleus RNA Sequencing Reveals Loss of Distal Convoluted Tubule 1 Renal Tubules in HIV Viral Protein R Transgenic Mice.

单核 RNA 测序揭示 HIV 病毒蛋白 R 转基因小鼠远端肾小管 1 的缺失

Latt Khun Zaw, Yoshida Teruhiko, Shrivastav Shashi, Abedini Amin, Reece Jeff M, Sun Zeguo, Lee Hewang, Okamoto Koji, Dagur Pradeep, Ishimoto Yu, Heymann Jurgen, Zhao Yongmei, Chung Joon-Yong, Hewitt Stephen, Jose Pedro A, Lee Kyung, He John Cijiang, Winkler Cheryl A, Knepper Mark A, Kino Tomoshige, Rosenberg Avi Z, Susztak Katalin, Kopp Jeffrey B

A novel ARPKD mouse model with near-complete deletion of the Polycystic Kidney and Hepatic Disease 1 (Pkhd1) genomic locus presents with multiple phenotypes but not renal cysts

一种新型ARPKD小鼠模型,其多囊肾和肝病1(Pkhd1)基因组位点几乎完全缺失,表现出多种表型,但不出现肾囊肿。

Ishimoto, Yu; Menezes, Luis F; Zhou, Fang; Yoshida, Teruhiko; Komori, Taishi; Qiu, Jiahe; Young, Marian F; Lu, Huiyan; Potapova, Svetlana; Outeda, Patricia; Watnick, Terry; Germino, Gregory G

An intestinal organoid-based platform that recreates susceptibility to T-cell-mediated tissue injury

一种基于肠道类器官的平台,可重现对T细胞介导的组织损伤的易感性

Matsuzawa-Ishimoto, Yu; Hine, Ashley; Shono, Yusuke; Rudensky, Eugene; Lazrak, Amina; Yeung, Frank; Neil, Jessica A; Yao, Xiaomin; Chen, Ying-Han; Heaney, Thomas; Schuster, Samantha L; Zwack, Erin E; Axelrad, Jordan E; Hudesman, David; Tsai, Jennifer J; Nichols, Katherine; Dewan, M Zahidunnabi; Cammer, Michael; Beal, Allison; Hoffman, Sandra; Geddes, Brad; Bertin, John; Liu, Chen; Torres, Victor J; Loke, P'ng; van den Brink, Marcel R M; Cadwell, Ken

Gut epithelial TSC1/mTOR controls RIPK3-dependent necroptosis in intestinal inflammation and cancer

肠道上皮细胞TSC1/mTOR调控肠道炎症和癌症中的RIPK3依赖性坏死性凋亡

Xie, Yadong; Zhao, Yifan; Shi, Lei; Li, Wei; Chen, Kun; Li, Min; Chen, Xia; Zhang, Haiwei; Li, Tiantian; Matsuzawa-Ishimoto, Yu; Yao, Xiaomin; Shao, Dianhui; Ke, Zunfu; Li, Jian; Chen, Yan; Zhang, Xiaoming; Cui, Jun; Cui, Shuzhong; Leng, Qibin; Cadwell, Ken; Li, Xiaoxia; Wei, Hong; Zhang, Haibing; Li, Huabin; Xiao, Hui

Physiological and pathophysiological role of reactive oxygen species and reactive nitrogen species in the kidney

活性氧和活性氮在肾脏中的生理和病理生理作用

Ishimoto, Yu; Tanaka, Tetsuhiro; Yoshida, Yoko; Inagi, Reiko