Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model
在小鼠异种移植模型中,靶向 AKT/mTOR 通路可减弱结直肠癌循环肿瘤细胞的转移潜能。
期刊:Molecular Oncology
影响因子:4.5
doi:10.1002/1878-0261.70024
Smit, Daniel J; Pereira-Veiga, Thais; Brauer, Helena; Horn, Michael; Nissen, Paula; Mair, Thomas; Siebels, Bente; Voß, Hannah; Zhuang, Ruimeng; Haider, Marie-Therese; Loreth, Desiree; Iskhakova, Margarita; Lindemann, Bele; Kött, Julian; Cayrefourcq, Laure; Wellbrock, Jasmin; Schlüter, Hartmut; Pantel, Klaus; Alix-Panabières, Catherine; Jücker, Manfred
肿瘤
肠癌
mTOR
肿瘤免疫
信号转导
细胞生物学
肿瘤细胞
AKT