日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Acellular, bioresorbable, ultra-purified alginate gel implantation for intervertebral disc herniation: Phase 1/2, open-label, non-randomized clinical trials

用于治疗椎间盘突出症的无细胞、可生物吸收、超纯藻酸盐凝胶植入：I/II期、开放标签、非随机临床试验

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-59715-0
Yamada, Katsuhisa; Hyakumachi, Takahiko; Kokabu, Terufumi; Maeda, Kenichiro; Isoe, Toshiyuki; Tha, Khin Khin; M Ito, Yoichi; Ohnishi, Takashi; Endo, Tsutomu; Ukeba, Daisuke; Tachi, Hiroyuki; Abe, Yuichiro; Ishikawa, Yoko; Yokota, Nozomi; Miyakoshi, Takashi; Sugita, Osamu; Sato, Norihiro; Iwasaki, Norimasa; Sudo, Hideki
细胞生物学
发表日期：2025
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Multicenter phase II trial of trastuzumab and docetaxel for HER2-positive salivary gland cancer

曲妥珠单抗联合多西他赛治疗HER2阳性唾液腺癌的多中心II期临床试验

期刊:Japanese Journal of Clinical Oncology
影响因子:2.2
doi:10.1093/jjco/hyaf106
Kano, Satoshi; Kiyota, Naomi; Kinoshita, Ichiro; Tada, Yuichiro; Ijichi, Kei; Yamazaki, Tomoko; Shimizu, Yasushi; Hatanaka, Yutaka; Tsuda, Hitoshi; Morinaga, Shojiroh; Matsuno, Yoshihiro; Ito, Yoichi M; Nishimoto, Naoki; Kobayashi, Keiko; Isoe, Toshiyuki; Noguchi, Takuro; Homma, Akihiro; Dosaka-Akita, Hirotoshi
肿瘤
肿瘤免疫
HER2
发表日期：2025
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Protocol for treating lumbar spinal canal stenosis with a combination of ultrapurified, allogenic bone marrow-derived mesenchymal stem cells and in situ-forming gel: a multicentre, prospective, double-blind randomised controlled trial

采用超纯化异体骨髓间充质干细胞联合原位形成凝胶治疗腰椎管狭窄症的方案：一项多中心、前瞻性、双盲随机对照试验

期刊:BMJ Open
影响因子:2.3
doi:10.1136/bmjopen-2022-065476
Sudo, Hideki; Miyakoshi, Takashi; Watanabe, Yudai; Ito, Yoichi M; Kahata, Kaoru; Tha, Khin Khin; Yokota, Nozomi; Kato, Hiroe; Terada, Tomoko; Iwasaki, Norimasa; Arato, Teruyo; Sato, Norihiro; Isoe, Toshiyuki
细胞生物学
发育与干细胞
干细胞
发表日期：2023
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Status of the Current Treatment Options and Potential Future Targets in Uterine Leiomyosarcoma: A Review

子宫平滑肌肉瘤当前治疗方案及潜在未来靶点：综述

期刊:Cancers
影响因子:4.4
doi:10.3390/cancers14051180
Asano, Hiroshi; Isoe, Toshiyuki; Ito, Yoichi M; Nishimoto, Naoki; Watanabe, Yudai; Yokoshiki, Saki; Watari, Hidemichi
发表日期：2022
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Exploratory clinical trial on the safety and capability of dMD-001 in lumbar disc herniation: Study protocol for a first-in-human pilot study

dMD-001治疗腰椎间盘突出症的安全性和有效性探索性临床试验：首次人体试验方案

期刊:Contemporary Clinical Trials Communications
影响因子:1.4
doi:10.1016/j.conctc.2021.100805
Yamada, Katsuhisa; Kenichiro, Maeda; Ito, Yoichi M; Inage, Fujio; Isoe, Toshiyuki; Yokota, Nozomi; Sugita, Osamu; Sato, Norihiro; Tha, Khin Khin; Iwasaki, Norimasa; Arato, Teruyo; Sudo, Hideki
发表日期：2021
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Safety and efficacy of amnion-derived mesenchymal stem cells (AM01) in patients with steroid-refractory acute graft-versus-host disease after allogeneic haematopoietic stem cell transplantation: a study protocol for a phase I/II Japanese trial

羊膜间充质干细胞（AM01）治疗异基因造血干细胞移植后类固醇难治性急性移植物抗宿主病患者的安全性和有效性：一项日本I/II期临床试验的研究方案

期刊:BMJ Open
影响因子:2.3
doi:10.1136/bmjopen-2018-026403
Yamahara, Kenichi; Hamada, Akiko; Soma, Toshihiro; Okamoto, Rika; Okada, Masaya; Yoshihara, Satoshi; Yoshihara, Kyoko; Ikegame, Kazuhiro; Tamaki, Hiroya; Kaida, Katsuji; Inoue, Takayuki; Ohsugi, Yuko; Nishikawa, Hiroki; Hayashi, Hiroshi; Ito, Yoichi M; Iijima, Hiroaki; Ohnishi, Shunsuke; Hashimoto, Daigo; Isoe, Toshiyuki; Teshima, Takanori; Ogawa, Hiroyasu; Sato, Norihiro; Fujimori, Yoshihiro
细胞生物学
发育与干细胞
干细胞
发表日期：2019
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Open-label clinical trial of bezafibrate treatment in patients with fatty acid oxidation disorders in Japan; 2nd report QOL survey

日本开展的贝扎贝特治疗脂肪酸氧化障碍患者的开放标签临床试验；第二份生活质量调查报告

期刊:Molecular Genetics and Metabolism Reports
影响因子:1.9
doi:10.1016/j.ymgmr.2019.100496
Shiraishi, Hideaki; Yamada, Kenji; Oki, Eishin; Ishige, Mika; Fukao, Toshiyuki; Hamada, Yusuke; Sakai, Norio; Ochi, Fumihiro; Watanabe, Asami; Kawakami, Sanae; Kuzume, Kazuyo; Watanabe, Kenji; Sameshima, Koji; Nakamagoe, Kiyotaka; Tamaoka, Akira; Asahina, Naoko; Yokoshiki, Saki; Miyakoshi, Takashi; Oba, Koji; Isoe, Toshiyuki; Hayashi, Hiroshi; Yamaguchi, Seiji; Sato, Norihiro
代谢
发表日期：2019
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Evaluation of amnion-derived mesenchymal stem cells for treatment-resistant moderate Crohn's disease: study protocol for a phase I/II, dual-centre, open-label, uncontrolled, dose-response trial

评估羊膜来源间充质干细胞治疗难治性中度克罗恩病的疗效：一项 I/II 期、双中心、开放标签、非对照、剂量反应试验的研究方案

期刊:BMJ Open Gastroenterology
影响因子:2.9
doi:10.1136/bmjgast-2018-000206
Otagiri, Shinsuke; Ohnishi, Shunsuke; Miura, Arisa; Hayashi, Hiroshi; Kumagai, Izumi; Ito, Yoichi M; Katsurada, Takehiko; Nakamura, Shiro; Okamoto, Rika; Yamahara, Kenichi; Cho, Kyu Yong; Isoe, Toshiyuki; Sato, Norihiro; Sakamoto, Naoya
发育与干细胞
细胞生物学
克罗恩病
干细胞
发表日期：2018
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Open-label clinical trial of bezafibrate treatment in patients with fatty acid oxidation disorders in Japan

日本开展贝扎贝特治疗脂肪酸氧化障碍患者的开放标签临床试验

期刊:Molecular Genetics and Metabolism Reports
影响因子:1.9
doi:10.1016/j.ymgmr.2018.02.003
Yamada, Kenji; Shiraishi, Hideaki; Oki, Eishin; Ishige, Mika; Fukao, Toshiyuki; Hamada, Yusuke; Sakai, Norio; Ochi, Fumihiro; Watanabe, Asami; Kawakami, Sanae; Kuzume, Kazuyo; Watanabe, Kenji; Sameshima, Koji; Nakamagoe, Kiyotaka; Tamaoka, Akira; Asahina, Naoko; Yokoshiki, Saki; Miyakoshi, Takashi; Ono, Kota; Oba, Koji; Isoe, Toshiyuki; Hayashi, Hiroshi; Yamaguchi, Seiji; Sato, Norihiro
代谢
发表日期：2018
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Anti-tumor activity and tumor vessel normalization by the vascular endothelial growth factor receptor tyrosine kinase inhibitor KRN951 in a rat peritoneal disseminated tumor model.

血管内皮生长因子受体酪氨酸激酶抑制剂 KRN951 在大鼠腹膜播散性肿瘤模型中表现出抗肿瘤活性和肿瘤血管正常化作用

期刊:Cancer Science
影响因子:4.3
doi:10.1111/j.1349-7006.2007.00724.x
Taguchi Eri, Nakamura Kazuhide, Miura Toru, Shibuya Masabumi, Isoe Toshiyuki
肿瘤
Rat
肿瘤免疫
发表日期：2008
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