日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Targeting NAD+ Metabolism Vulnerability in FH-Deficient Hereditary Leiomyomatosis and Renal Cell Carcinoma with the Novel NAMPT Inhibitor OT-82.

利用新型 NAMPT 抑制剂 OT-82 靶向 FH 缺陷型遗传性平滑肌瘤病和肾细胞癌中的 NAD+ 代谢脆弱性

期刊:Molecular Cancer Therapeutics
影响因子:5.5
doi:10.1158/1535-7163.MCT-24-0225
Najera Susana S, Ricketts Christopher J, Schmidt Laura S, Medina Julia I, Saito Keita, Ileva Lilia, Brender Jeffrey R, James Amy M, Peer Cody J, Gouker Brad, Karim Baktiar O, Chernova Olga, Wells Catherine, Wei Ming-Hui, Yang Youfeng, Zhang Xiaohu, Klumpp-Thomas Carleen, Travers Jameson, Chen Lu, Wilson Kelli M, Issaq Sameer H, Figg William D, Difilippantonio Simone, Kalen Joseph D, Krishna Murali C, Thomas Craig J, Ceribelli Michele, Heske Christine M, Crooks Daniel R, Meier Jordan L
代谢
细胞生物学
肿瘤免疫
发表日期：2025
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Total versus robotic-assisted unicompartmental knee replacement (TRAKER) for medial compartment osteorthritis: a randomized controlled trial

内侧间室骨关节炎全膝关节置换术与机器人辅助单髁膝关节置换术（TRAKER）的比较：一项随机对照试验

期刊:Bone Joint Open
影响因子:
doi:10.1302/2633-1462.62.BJO-2024-0155.R1
Clement, Nick D; Scott, Chloe E H; Macpherson, Gavin J; Simpson, Philip M; Leitch, Gillian; Patton, James T; Ahmed, Issaq; Amin, Anish K; Gaston, Paul; Goudie, Ewan; Goudie, Stuart; Macdonald, Deborah M; Martinson, Eliott; Moran, Matthew; Wade, Fazer
关节炎
发表日期：2025
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Inhibition of NAD+-Dependent Metabolic Processes Induces Cellular Necrosis and Tumor Regression in Rhabdomyosarcoma Models

抑制NAD+依赖性代谢过程可诱导横纹肌肉瘤模型中的细胞坏死和肿瘤消退

期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-23-0200
McKay-Corkum, Grace B; Collins, Victor J; Yeung, Choh; Ito, Takeshi; Issaq, Sameer H; Holland, David; Vulikh, Ksenia; Zhang, Yiping; Lee, Unsun; Lei, Haiyan; Mendoza, Arnulfo; Shern, Jack F; Yohe, Marielle E; Yamamoto, Kazutoshi; Wilson, Kelli; Ji, Jiuping; Karim, Baktiar O; Thomas, Craig J; Krishna, Murali C; Neckers, Leonard M; Heske, Christine M
肿瘤
肿瘤免疫
代谢
细胞生物学
横纹肌肉瘤
毒理研究
发表日期：2023
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Glutaminase-1 (GLS1) inhibition limits metastatic progression in osteosarcoma

谷氨酰胺酶-1（GLS1）抑制可限制骨肉瘤的转移进展

期刊:Cancer & Metabolism
影响因子:6
doi:10.1186/s40170-020-0209-8
L Ren #, V Ruiz-Rodado #, T Dowdy, S Huang, S H Issaq, J Beck, H Wang, C Tran Hoang, A Lita, M Larion, A K LeBlanc
肿瘤
骨肉瘤
发表日期：2020
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Inhibition of nicotinamide phosphoribosyltransferase (NAMPT) with OT-82 induces DNA damage, cell death, and suppression of tumor growth in preclinical models of Ewing sarcoma

使用 OT-82 抑制烟酰胺磷酸核糖转移酶 (NAMPT) 可导致尤文氏肉瘤临床前模型中的 DNA 损伤、细胞死亡和肿瘤生长抑制

期刊:Oncogenesis
影响因子:5.9
doi:10.1038/s41389-020-00264-0
Anna E Gibson, Choh Yeung, Sameer H Issaq, Victor J Collins, Michael Gouzoulis, Yiping Zhang, Jiuping Ji, Arnulfo Mendoza, Christine M Heske
细胞生物学
肿瘤
其它细胞
发表日期：2020
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EWS-FLI1-regulated Serine Synthesis and Exogenous Serine are Necessary for Ewing Sarcoma Cellular Proliferation and Tumor Growth

EWS-FLI1 调节的丝氨酸合成和外源丝氨酸是尤文肉瘤细胞增殖和肿瘤生长所必需的

期刊:Molecular Cancer Therapeutics
影响因子:5.3
doi:10.1158/1535-7163.MCT-19-0748
Sameer H Issaq, Arnulfo Mendoza, Ria Kidner, Tracy I Rosales, Damien Y Duveau, Christine M Heske, Jason M Rohde, Matthew B Boxer, Craig J Thomas, Ralph J DeBerardinis, Lee J Helman
肿瘤
肿瘤细胞
发表日期：2020
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Clinical performance of a semi-quantitative assay for SARS-CoV2 IgG and SARS-CoV2 IgM antibodies

SARS-CoV-2 IgG 和 SARS-CoV-2 IgM 抗体半定量检测的临床性能

期刊:Clinica Chimica Acta
影响因子:2.9
doi:10.1016/j.cca.2020.09.023
Jung, Joanna; Garnett, Emily; Jariwala, Purviben; Pham, Hue; Huang, Rongrong; Benzi, Eduardo; Issaq, Niveen; Matzuk, Martin; Singh, Ila; Devaraj, Sridevi
SARS-CoV-2
IgM
IgG
发表日期：2020
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Targeting metabolic dependencies in pediatric cancer

针对儿童癌症的代谢依赖性进行治疗

期刊:Current Opinion in Pediatrics
影响因子:2.5
doi:10.1097/MOP.0000000000000853
Issaq, Sameer H; Heske, Christine M
肿瘤
肿瘤免疫
代谢
发表日期：2020
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Targeting Glycolysis through Inhibition of Lactate Dehydrogenase Impairs Tumor Growth in Preclinical Models of Ewing Sarcoma

通过抑制乳酸脱氢酶靶向糖酵解可抑制尤文氏肉瘤临床前模型中的肿瘤生长

期刊:Cancer Research
影响因子:12.5
doi:10.1158/0008-5472.CAN-19-0217
Choh Yeung, Anna E Gibson, Sameer H Issaq, Nobu Oshima, Joshua T Baumgart, Leah D Edessa, Ganesha Rai, Daniel J Urban, Michelle S Johnson, Gloria A Benavides, Giuseppe L Squadrito, Marielle E Yohe, Haiyan Lei, Sandy Eldridge, John Hamre 3rd, Tyrone Dowdy, Victor Ruiz-Rodado, Adrian Lita, Arnulfo Men
肿瘤
发表日期：2019
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Glutamine synthetase is necessary for sarcoma adaptation to glutamine deprivation and tumor growth

谷氨酰胺合成酶是肉瘤适应谷氨酰胺缺乏和肿瘤生长所必需的

期刊:Oncogenesis
影响因子:5.9
doi:10.1038/s41389-019-0129-z
Sameer H Issaq, Arnulfo Mendoza, Stephen D Fox, Lee J Helman
肿瘤
发表日期：2019
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