日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Brain organoid models of SZT2-related disease reveal an overproduction of outer radial glial cells through mTORC1 activation.

SZT2 相关疾病的脑类器官模型显示,通过 mTORC1 激活导致外放射状胶质细胞过度生成。

Sato Emi, Nakamura Yuji, Fujimoto Masanori, Shimada Issei S, Iwaki Toshihiko, Ieda Daisuke, Negishi Yutaka, Hattori Ayako, Kato Yoichi, Saitoh Shinji

Aberrant activation of IL-6/JAK/STAT3/FOSL1 signaling induces renal abnormalities in a Xenopus model of Joubert syndrome-related disorders.

IL-6/JAK/STAT3/FOSL1 信号异常激活可导致 Joubert 综合征相关疾病的非洲爪蟾模型出现肾脏异常

Uuganbayar Udval, Ninomiya Hiromasa, Shimada Issei S, Yamada Chisato, Kanie Mayu, Kawai Shinji, Asai Takahiro, Miyoshi-Akiyama Toru, Itoh Masayuki, Hashimoto Yutaka, Kato Yoichi

Biallelic null variants in PNPLA8 cause microcephaly by reducing the number of basal radial glia

PNPLA8 中的双等位基因无效变异通过减少基底放射状胶质细胞的数量导致小头畸形

Yuji Nakamura, Issei S Shimada, Reza Maroofian, Micol Falabella, Maha S Zaki, Masanori Fujimoto, Emi Sato, Hiroshi Takase, Shiho Aoki, Akihiko Miyauchi, Eriko Koshimizu, Satoko Miyatake, Yuko Arioka, Mizuki Honda, Takayoshi Higashi, Fuyuki Miya, Yukimune Okubo, Isamu Ogawa, Annarita Scardamaglia, Mo

The binding of LARP6 and DNAAF6 in biomolecular condensates influences ciliogenesis of multiciliated cells

LARP6 和 DNAAF6 在生物分子凝聚体中的结合影响多纤毛细胞的纤毛发生。

Ryan Earwood,Hiromasa Ninomiya,Hao Wang,Issei S Shimada,Mia Stroud,Diana Perez,Udval Uuganbayar,Chisato Yamada,Toru Akiyama-Miyoshi,Branko Stefanovic,Yoichi Kato

Transcription Factor 23 is an Essential Determinant of Murine Term Parturition.

转录因子 23 是小鼠足月分娩的重要决定因素

Minisy Fatma M, Shawki Hossam H, Fujita Tsubasa, Moustafa Ahmed M, Sener Rumeysa, Nishio Youske, Shimada Issei S, Saitoh Shinji, Sugiura-Ogasawara Mayumi, Oishi Hisashi

Interactions between TULP3 tubby domain and ARL13B amphipathic helix promote lipidated protein transport to cilia

TULP3 tubby 结构域与 ARL13B 两亲螺旋之间的相互作用促进脂质蛋白向纤毛的运输

Vivek Reddy Palicharla, Sun-Hee Hwang, Bandarigoda N Somatilaka, Emilie Legué, Issei S Shimada, Nicole E Familiari, Vanna M Tran, Jeffrey B Woodruff, Karel F Liem Jr, Saikat Mukhopadhyay

Derepression of sonic hedgehog signaling upon Gpr161 deletion unravels forebrain and ventricular abnormalities

Gpr161缺失导致音猬因子信号通路去抑制,从而揭示前脑和脑室异常

Shimada, Issei S; Somatilaka, Bandarigoda N; Hwang, Sun-Hee; Anderson, Ashley G; Shelton, John M; Rajaram, Veena; Konopka, Genevieve; Mukhopadhyay, Saikat

Prdm16 is required for the maintenance of neural stem cells in the postnatal forebrain and their differentiation into ependymal cells.

Prdm16 是维持出生后前脑神经干细胞及其分化为室管膜细胞所必需的

Shimada Issei S, Acar Melih, Burgess Rebecca J, Zhao Zhiyu, Morrison Sean J

Tubby family proteins are adapters for ciliary trafficking of integral membrane proteins

Tubby 家族蛋白是纤毛运输膜蛋白的适配器

Hemant B Badgandi, Sun-Hee Hwang, Issei S Shimada, Evan Loriot, Saikat Mukhopadhyay

Trafficking to the primary cilium membrane

运输至初级纤毛膜

Mukhopadhyay, Saikat; Badgandi, Hemant B; Hwang, Sun-Hee; Somatilaka, Bandarigoda; Shimada, Issei S; Pal, Kasturi