日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structural insights into the Thermus thermophilus type IV pilus machinery assembling two distinct pili

对嗜热栖热菌IV型菌毛组装机制的结构解析,揭示了两种不同菌毛的组装过程。

Neuhaus, Alexander; McLaren, Mathew; Isupov, Michail N; Gaines, Matthew; Buzzard, Emma; Sikora, Mateusz; Hanus, Cyril; Daum, Bertram; Averhoff, Beate; Gold, Vicki A M

UFC1 reveals the multifactorial and plastic nature of oxyanion holes in E2 conjugating enzymes.

UFC1 揭示了 E2 结合酶中氧阴离子孔的多因素和可塑性

Kumar Manoj, Banerjee Sayanika, Cohen-Kfir Einav, Mitelberg Marissa Basia, Tiwari Suryakant, Isupov Michail N, Dessau Moshe, Wiener Reuven

Cryo-EM resolves the structure of the archaeal dsDNA virus HFTV1 from head to tail

冷冻电镜解析了古菌双链DNA病毒HFTV1从头到尾的结构。

Zhang, Daniel X; Isupov, Michail N; Davies, Rebecca M; Schwarzer, Sabine; McLaren, Mathew; Stuart, William S; Gold, Vicki A M; Oksanen, Hanna M; Quax, Tessa E F; Daum, Bertram

Unusual cell surfaces, pili, and archaella of Thermoplasmatales archaea

热原体目古菌的异常细胞表面、菌毛和古菌体

Gaines, Matthew C; Isupov, Michail N; McLaren, Mathew; Haque, Risat Ul; Recalde, Alejandra; Bargiela, Rafael; Gold, Vicki A M; Albers, Sonja-Verena; Golyshin, Peter N; Golyshina, Olga V; Daum, Bertram

Establishment of an efficient one-step enzymatic synthesis of cyclic-2,3-diphosphoglycerate

建立一种高效的一步酶法合成环状-2,3-二磷酸甘油酸酯的方法

Stracke, Christina; Meyer, Benjamin H; De Rose, Simone A; Ferrandi, Erica Elisa; Kublanov, Ilya V; Isupov, Michail N; Harmer, Nicholas J; Monti, Daniela; Littlechild, Jennifer; Müller, Felix; Snoep, Jacky L; Bräsen, Christopher; Siebers, Bettina

Functional and structural insights into a thermostable (S)-selective amine transaminase and its improved substrate scope by protein engineering

通过蛋白质工程技术,深入了解一种耐热(S)选择性胺转氨酶的功能和结构,并提高其底物范围。

Patti, Stefania; De Rose, Simone A; Isupov, Michail N; Magrini Alunno, Ilaria; Riva, Sergio; Ferrandi, Erica Elisa; Littlechild, Jennifer A; Monti, Daniela

Structure and catalytic mechanism of methylisocitrate lyase, a potential drug target against Coxiella burnetii.

甲基异柠檬酸裂解酶的结构和催化机制,一种潜在的抗伯氏考克斯体药物靶点

Stuart William S, Jenkins Christopher H, Ireland Philip M, Isupov Michail N, Norville Isobel H, Harmer Nicholas J

Triosephosphate isomerase from Fasciola hepatica: high-resolution crystal structure as a drug target

肝片吸虫的磷酸丙糖异构酶:高分辨率晶体结构作为药物靶点

Kontellas, Georgios; Studholme, David J; van der Giezen, Mark; Timson, David J; Littlechild, Jennifer A; Isupov, Michail N

CryoEM reveals the structure of an archaeal pilus involved in twitching motility

冷冻电镜揭示了参与颤搐运动的古菌菌毛的结构

Gaines, Matthew C; Sivabalasarma, Shamphavi; Isupov, Michail N; Haque, Risat Ul; McLaren, Mathew; Hanus, Cyril; Gold, Vicki A M; Albers, Sonja-Verena; Daum, Bertram

Structure of the two-component S-layer of the archaeon Sulfolobus acidocaldarius

古菌嗜酸热硫化叶菌双组分S层的结构

Gambelli, Lavinia; McLaren, Mathew; Conners, Rebecca; Sanders, Kelly; Gaines, Matthew C; Clark, Lewis; Gold, Vicki A M; Kattnig, Daniel; Sikora, Mateusz; Hanus, Cyril; Isupov, Michail N; Daum, Bertram