日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Synergistic involvement of the NZF domains of the LUBAC accessory subunits HOIL-1L and SHARPIN in the regulation of LUBAC function

LUBAC辅助亚基HOIL-1L和SHARPIN的NZF结构域协同参与LUBAC功能的调控

期刊:Cell Death & Disease
影响因子:9.6
doi:10.1038/s41419-024-07199-z
Toda, Yusuke; Fujita, Hiroaki; Mino, Koshiki; Koyama, Takuto; Matsuoka, Seiji; Kaizuka, Toshie; Agawa, Mari; Matsumoto, Shigeyuki; Idei, Akiko; Nishikori, Momoko; Okuno, Yasushi; Osada, Hiroyuki; Yoshida, Minoru; Takaori-Kondo, Akifumi; Iwai, Kazuhiro
信号转导
发表日期：2024
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Author Correction: HOIL-1L deficiency induces cell cycle alteration which causes immaturity of skeletal muscle and cardiomyocytes

作者更正：HOIL-1L 缺乏会诱导细胞周期改变，从而导致骨骼肌和心肌细胞发育不成熟。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-024-61046-x
Akagi, Kentaro; Baba, Shiro; Fujita, Hiroaki; Fuseya, Yasuhiro; Yoshinaga, Daisuke; Kubota, Hirohito; Kume, Eitaro; Fukumura, Fumiaki; Matsuda, Koichi; Tanaka, Takayuki; Hirata, Takuya; Saito, Megumu K; Iwai, Kazuhiro; Takita, Junko
细胞生物学
发育与干细胞
发表日期：2024
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Solution structure of the HOIL-1L NZF domain reveals a conformational switch regulating linear ubiquitin affinity

HOIL-1L NZF结构域的溶液结构揭示了一种构象转换，该转换调控线性泛素亲和力。

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2023.105165
Walinda, Erik; Sugase, Kenji; Ishii, Naoki; Shirakawa, Masahiro; Iwai, Kazuhiro; Morimoto, Daichi
信号转导
发表日期：2023
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Biochemistry, Pathophysiology, and Regulation of Linear Ubiquitination: Intricate Regulation by Coordinated Functions of the Associated Ligase and Deubiquitinase

线性泛素化的生物化学、病理生理学和调控：相关连接酶和去泛素酶协同功能的复杂调控

期刊:Cells
影响因子:5.2
doi:10.3390/cells10102706
Fuseya, Yasuhiro; Iwai, Kazuhiro
信号转导
泛素化
表观遗传
发表日期：2021
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Cooperative Domain Formation by Homologous Motifs in HOIL-1L and SHARPIN Plays A Crucial Role in LUBAC Stabilization

HOIL-1L 和 SHARPIN 中同源基序的协同结构域形成在 LUBAC 稳定中起着至关重要的作用

期刊:Cell Reports
影响因子:6.9
doi:10.1016/j.celrep.2018.03.112
Fujita, Hiroaki; Tokunaga, Akira; Shimizu, Satoshi; Whiting, Amanda L; Aguilar-Alonso, Francisco; Takagi, Kenji; Walinda, Erik; Sasaki, Yoshiteru; Shimokawa, Taketo; Mizushima, Tsunehiro; Ohki, Izuru; Ariyoshi, Mariko; Tochio, Hidehito; Bernal, Federico; Shirakawa, Masahiro; Iwai, Kazuhiro
发表日期：2018
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HIF and HOIL-1L-mediated PKCζ degradation stabilizes plasma membrane Na,K-ATPase to protect against hypoxia-induced lung injury

HIF 和 HOIL-1L 介导的 PKCζ 降解可稳定质膜 Na,K-ATPase，从而保护肺免受缺氧引起的损伤。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1713563114
Magnani, Natalia D; Dada, Laura A; Queisser, Markus A; Brazee, Patricia L; Welch, Lynn C; Anekalla, Kishore R; Zhou, Guofei; Vagin, Olga; Misharin, Alexander V; Budinger, G R Scott; Iwai, Kazuhiro; Ciechanover, Aaron J; Sznajder, Jacob I
PKC
发表日期：2017
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Survival of mature T cells depends on signaling through HOIP

成熟T细胞的存活依赖于HOIP信号通路。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/srep36135
Okamura, Kazumi; Kitamura, Akiko; Sasaki, Yoshiteru; Chung, Doo Hyun; Kagami, Shoji; Iwai, Kazuhiro; Yasutomo, Koji
信号转导
T细胞
T细胞
免疫/内分泌
细胞生物学
发表日期：2016
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Phenotypic complementation of genetic immunodeficiency by chronic herpesvirus infection

慢性疱疹病毒感染对遗传性免疫缺陷的表型互补作用

期刊:Elife
影响因子:6.4
doi:10.7554/eLife.04494
MacDuff, Donna A; Reese, Tiffany A; Kimmey, Jacqueline M; Weiss, Leslie A; Song, Christina; Zhang, Xin; Kambal, Amal; Duan, Erning; Carrero, Javier A; Boisson, Bertrand; Laplantine, Emmanuel; Israel, Alain; Picard, Capucine; Colonna, Marco; Edelson, Brian T; Sibley, L David; Stallings, Christina L; Casanova, Jean-Laurent; Iwai, Kazuhiro; Virgin, Herbert W
炎症/感染
免疫/内分泌
疱疹
微生物学
发表日期：2015
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LUBAC Formation Is Impaired in the Livers of Mice with MCD-Dependent Nonalcoholic Steatohepatitis

在患有MCD依赖性非酒精性脂肪性肝炎的小鼠肝脏中，LUBAC的形成受损

期刊:Mediators of Inflammation
影响因子:4.2
doi:10.1155/2015/125380
Matsunaga, Yasuka; Nakatsu, Yusuke; Fukushima, Toshiaki; Okubo, Hirofumi; Iwashita, Misaki; Sakoda, Hideyuki; Fujishiro, Midori; Yamamotoya, Takeshi; Kushiyama, Akifumi; Takahashi, Shin-Ichiro; Tsuchiya, Yoshihiro; Kamata, Hideaki; Tokunaga, Fuminori; Iwai, Kazuhiro; Asano, Tomoichiro
肝炎
发表日期：2015
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HOIL-1L functions as the PKCζ ubiquitin ligase to promote lung tumor growth

HOIL-1L 作为 PKCζ 泛素连接酶，促进肺肿瘤生长

期刊:American Journal of Respiratory and Critical Care Medicine
影响因子:19.4
doi:10.1164/rccm.201403-0463OC
Queisser, Markus A; Dada, Laura A; Deiss-Yehiely, Nimrod; Angulo, Martin; Zhou, Guofei; Kouri, Fotini M; Knab, Lawrence M; Liu, Jing; Stegh, Alexander H; DeCamp, Malcolm M; Budinger, G R Scott; Chandel, Navdeep S; Ciechanover, Aaron; Iwai, Kazuhiro; Sznajder, Jacob I
肿瘤
PKC
肿瘤免疫
发表日期：2014
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