日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Metabolic Reprogramming of T Cells by Dual UCP2 and IL-17 Blockade Enhances Immunity Against Pancreatic Cancer.

通过 UCP2 和 IL-17 双重阻断对 T 细胞进行代谢重编程，增强对胰腺癌的免疫力。

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202513020
Liu Chuan-Teng, Yeh Chun-Chieh, Wu Tsai-Chen, Lin Chia-Hsin, Kuo Yi-Ting, Iwakura Yoichiro, Day Yuan-Ji, Drake Charles, Radojcic Vedran, Song Ying-Chyi, Wu Heng-Hsiung, Yen Hung-Rong
胰腺癌
细胞生物学
UCP2
IL-17
代谢重编程
发表日期：2026
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Colonic Engyodontium fungus triggers neutrophil antimicrobial activity to suppress Lactobacillus johnsonii-derived glutamic acid-maintained Tregs.

结肠 Engyodontium 真菌触发中性粒细胞抗菌活性，抑制由约翰逊乳杆菌衍生的谷氨酸维持的 Tregs。

期刊:Journal of Clinical Investigation
影响因子:13.6
doi:10.1172/JCI196788
Wang Xinying, Sun Haiyang, Tan Ying, Xu Shaoting, Liu Zishan, Ji Kaile, Qiu Ding, Deng Jianping, Feng Bingbing, Wu Xueting, Iwakura Yoichiro, Chen Minhu, Feng Rui, Huang Chanyan, Tang Ce
细胞生物学
粒细胞
ENG
Treg
中性粒细胞
发表日期：2026
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Interleukin-17A Orchestrates Lung Injury and Remodeling Through p53 and uPA System Crosstalk.

白细胞介素-17A通过p53和uPA系统相互作用来调控肺损伤和重塑。

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms27041841
Das Durgesh Nandini, Balnadupete Akarsha, Shetty Rashmi, Gopu Venkadesa Perumal, Sajjan Rushil, Bhandary Yashodhar P, Marudamuthu Amarnath S, Oliver Christian, Patel Aarav, Patel Aryan, Samten Buka, Iwakura Yoichiro, Tang Hua, Citrin Deborah E, Peters Jay, Shetty Sreerama
细胞生物学
P53
uPA
发表日期：2026
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Contribution of CARD9 signaling to wound healing in skin promoted by topical administration of heat-killed Enterococcus faecalis strain KH2 and the involvement of Dectin-2

CARD9信号通路在局部应用热灭活粪肠球菌KH2菌株促进的皮肤伤口愈合中的作用以及Dectin-2的参与

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2025.1550934
Kurosaka, Shiho; Tanno, Hiromasa; Hirose, Minako; Kamada, Wakana; Takayashiki, Rena; Sone, Ikue; Sato, Yuki; Watanabe, Takumi; Ishi, Shinyo; Shoji, Miki; Imai, Yoshimichi; Sato, Ko; Ishii, Keiko; Hara, Hiromitsu; Yamasaki, Sho; Saijo, Shinobu; Iwakura, Yoichiro; Kawakami, Kazuyoshi; Kanno, Emi
信号转导
发表日期：2025
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Enhanced Innate Immunity Mediated by IL-36α in Atopic Dermatitis and Differences in Cytokine Profiles of Lymphocytes in the Skin and Draining Lymph Nodes

特应性皮炎中IL-36α介导的先天免疫增强以及皮肤和引流淋巴结中淋巴细胞细胞因子谱的差异

期刊:Biomolecules
影响因子:4.8
doi:10.3390/biom15060817
Ichikawa, Ayaka; Nishimura, Mai; Ichishi, Masako; Imai, Yasutomo; Matsushima, Yoshiaki; Iwakura, Yoichiro; Watanabe, Masatoshi; Yamanishi, Kiyofumi; Yamanaka, Keiichi
细胞生物学
IL-3
免疫/内分泌
发表日期：2025
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Mipep deficiency in adipocytes impairs mitochondrial protein maturation and leads to systemic inflammation and metabolic dysfunctions.

脂肪细胞中 Mipep 缺乏会损害线粒体蛋白的成熟，并导致全身炎症和代谢功能障碍

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-97307-6
Nozaki Yuka, Kobayashi Masaki, Fukuoh Tomoyoshi, Ishimatsu Mamiko, Narita Takumi, Taki Kanari, Hirao Yuto, Ayabe Shota, Yokoyama Miku, Otani Yuina, Mizunoe Yuhei, Matsumoto Mami, Ohno Nobuhiko, Kaifu Tomonori, Okazaki Shogo, Goitsuka Ryo, Nakagawa Yoshimi, Shimano Hitoshi, Iwakura Yoichiro, Higami Yoshikazu
代谢
细胞生物学
炎症
线粒体
发表日期：2025
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Candida auris persists in the vaginal microaerobic niche in the absence of interleukin-17A

即使在缺乏白细胞介素-17A的情况下，耳念珠菌仍能在阴道微需氧环境中持续存在。

期刊:mSphere
影响因子:3.1
doi:10.1128/msphere.00446-25
Abe, Masahiro; Sadamoto, Sota; Nagamori, Akiko; Shinozaki, Minoru; Oiki, Sayoko; Otani, Amato; Koizumi, Ami; Shinohara, Takayuki; Iwakura, Yoichiro; Shibuya, Kazutoshi; Miyazaki, Yoshitsugu
细胞生物学
发表日期：2025
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Naturally arising memory-phenotype CD4(+) T lymphocytes contain an undifferentiated population that can generate T(H)1, T(H)17, and T(reg) cells

自然产生的记忆表型 CD4(+) T 淋巴细胞包含一个未分化的细胞群，该细胞群可以生成 T(H)1、T(H)17 和 T(reg) 细胞。

期刊:Science Advances
影响因子:12.5
doi:10.1126/sciadv.adq6618
Kawajiri, Akihisa; Li, Jing; Koinuma, Keita; Yang, Ziying; Yoon, Hye Jin; Yi, Jaeu; Nagashima, Hiroyuki; Ishii, Minami; Gao, Feng; Sato, Kosuke; Tayama, Shunichi; Harigae, Hideo; Iwakura, Yoichiro; Ishii, Naoto; Sher, Alan; Ishigaki, Kazuyoshi; Zhu, Jinfang; Kim, Kwang Soon; Kawabe, Takeshi
细胞生物学
T细胞
CD4
发表日期：2024
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Amelioration of Systemic Amyloidosis by Blocking IL-17A and Not by IL-17F, and Arteriosclerosis by Blocking Both IL-17A and IL-17F in an Inflammatory Skin Mouse Model

在炎症性皮肤小鼠模型中，阻断IL-17A而非IL-17F可改善全身性淀粉样变性，同时阻断IL-17A和IL-17F可改善动脉硬化。

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms252111617
Nakanishi, Takehisa; Iida, Shohei; Ichishi, Masako; Kondo, Makoto; Nishimura, Mai; Ichikawa, Ayaka; Matsushima, Yoshiaki; Iwakura, Yoichiro; Watanabe, Masatoshi; Yamanaka, Keiichi
IL-17F
炎症
IL-17
炎症/感染
IL-17A
Mouse
动脉粥样硬化
发表日期：2024
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Innate phase production of IFN-γ by memory and effector T cells expressing early activation marker CD69 during infection with Cryptococcus deneoformans in the lungs.

在肺部感染隐球菌期间，记忆和效应 T 细胞表达早期激活标志物 CD69，从而产生 IFN-γ 的先天阶段

期刊:Infection and Immunity
影响因子:2.8
doi:10.1128/iai.00024-24
Miyahara Anna, Umeki Aya, Sato Ko, Nomura Toshiki, Yamamoto Hideki, Miyasaka Tomomitsu, Tanno Daiki, Matsumoto Ikumi, Zong Tong, Kagesawa Takafumi, Oniyama Akiho, Kawamura Kotone, Yuan Xiaoliang, Yokoyama Rin, Kitai Yuki, Kanno Emi, Tanno Hiromasa, Hara Hiromitsu, Yamasaki Sho, Saijo Shinobu, Iwakura Yoichiro, Ishii Keiko, Kawakami Kazuyoshi
细胞生物学
CD6
肠道菌群
发表日期：2024
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