Iwanaga Ritsuko相关文献与解析，生知库 | 链接生命科学的每一步

Yamamoto Tomomi M, Iwanaga Ritsuko, Woodruff Elizabeth R, Elder Alan M, Petkov Alexander, Nurmemmedov Elmar, Eisenmesser Elan, Reigan Philip, Bitler Benjamin G, Brubaker Lindsay W

信号转导

发表日期：2026

文献求助收藏

Distinct Regulation of the ARF and TAp73 Tumor Suppressor Genes by the Transcription Factor E2F1 Enables Discrimination of Cancer Cells from Normal Growing Cells

转录因子E2F1对ARF和TAp73肿瘤抑制基因的独特调控作用，使得区分癌细胞和正常生长细胞成为可能。

期刊:Cells

影响因子:5.2

doi:10.3390/cells15010090

Zhou, Yaxuan; Nakajima, Rinka; Shirasawa, Mashiro; Fikriyanti, Mariana; Watanabe, Ako; Yang, Caiwei; Iwanaga, Ritsuko; Bradford, Andrew P; Kurayoshi, Kenta; Araki, Keigo; Ohtani, Kiyoshi

Utility of Tumor Suppressor E2F Target Gene Promoter Elements to Drive Gene Expression Specifically in Cancer Cells

肿瘤抑制因子E2F靶基因启动子元件在癌细胞中特异性驱动基因表达的应用

期刊:Cells

影响因子:5.2

doi:10.3390/cells14241953

Kurayoshi, Kenta; Tanaka, Masakazu; Nakajima, Rinka; Zhou, Yaxuan; Shirasawa, Mashiro; Fikriyanti, Mariana; Fujisawa, Jun-Ichi; Iwanaga, Ritsuko; Bradford, Andrew P; Araki, Keigo; Ohtani, Kiyoshi

Transcriptional Activation Mechanisms and Target Genes of the Oncogene Product Tax of Human T-Cell Leukemia Virus Type 1

人类T细胞白血病病毒1型癌基因产物Tax的转录激活机制和靶基因

期刊:Genes

影响因子:2.8

doi:10.3390/genes16101221

Shirasawa, Mashiro; Nakajima, Rinka; Zhou, Yaxuan; Fikriyanti, Mariana; Iwanaga, Ritsuko; Bradford, Andrew P; Kurayoshi, Kenta; Araki, Keigo; Ohtani, Kiyoshi

The Transcriptional Coactivator DEAD/H Box 5 (DDX5) Gene Is a Target of the Transcription Factor E2F1 Deregulated from the Tumor Suppressor pRB.

转录共激活因子 DEAD/H 盒 5 (DDX5) 基因是转录因子 E2F1 的靶标，而 E2F1 又受到肿瘤抑制因子 pRB 的调控

期刊:Genes

影响因子:2.8

doi:10.3390/genes16080929

Nakajima Rinka, Zhou Yaxuan, Shirasawa Mashiro, Fikriyanti Mariana, Iwanaga Ritsuko, Bradford Andrew P, Kurayoshi Kenta, Araki Keigo, Ohtani Kiyoshi

Combining EHMT and PARP Inhibition: A Strategy to Diminish Therapy-Resistant Ovarian Cancer Tumor Growth while Stimulating Immune Activation.

结合 EHMT 和 PARP 抑制：一种在抑制耐药性卵巢癌肿瘤生长的同时刺激免疫激活的策略

期刊:Molecular Cancer Therapeutics

影响因子:5.5

doi:10.1158/1535-7163.MCT-23-0613

Nguyen Lily L, Watson Zachary L, Ortega Raquel, Woodruff Elizabeth R, Jordan Kimberly R, Iwanaga Ritsuko, Yamamoto Tomomi M, Bailey Courtney A, To Francis, Jeong Abigail D, Guntupalli Saketh R, Behbakht Kian, Gibaja Veronica, Arnoult Nausica, Cocozaki Alexis, Chuong Edward B, Bitler Benjamin G

EHMT1/2 Inhibition Promotes Regression of Therapy-Resistant Ovarian Cancer Tumors in a CD8 T-cell-Dependent Manner.

EHMT1/2 抑制以 CD8 T 细胞依赖的方式促进耐药性卵巢癌肿瘤的消退

期刊:Molecular Cancer Research

影响因子:4.7

doi:10.1158/1541-7786.MCR-24-0067

Nguyen Lily L, Watson Zachary L, Ortega Raquel, Woodruff Elizabeth R, Jordan Kimberly R, Iwanaga Ritsuko, Yamamoto Tomomi M, Bailey Courtney A, To Francis, Lin Shujian, Villagomez Fabian R, Jeong Abigail D, Guntupalli Saketh R, Behbakht Kian, Gibaja Veronica, Arnoult Nausica, Chuong Edward B, Bitler Benjamin G

Activation of the CDK7 Gene, Coding for the Catalytic Subunit of the Cyclin-Dependent Kinase (CDK)-Activating Kinase (CAK) and General Transcription Factor II H, by the Trans-Activator Protein Tax of Human T-Cell Leukemia Virus Type-1.

人类 T 细胞白血病病毒 1 型的反式激活蛋白 Tax 激活 CDK7 基因，该基因编码细胞周期蛋白依赖性激酶 (CDK) 激活激酶 (CAK) 的催化亚基和通用转录因子 II H

期刊:Genes

影响因子:2.8

doi:10.3390/genes15081080

Shirasawa Mashiro, Nakajima Rinka, Zhou Yaxuan, Zhao Lin, Fikriyanti Mariana, Iwanaga Ritsuko, Bradford Andrew P, Kurayoshi Kenta, Araki Keigo, Ohtani Kiyoshi

Expanding Roles of the E2F-RB-p53 Pathway in Tumor Suppression

E2F-RB-p53通路在肿瘤抑制中的作用日益增强

期刊:Biology-Basel

影响因子:3.5

doi:10.3390/biology12121511

Zhou, Yaxuan; Nakajima, Rinka; Shirasawa, Mashiro; Fikriyanti, Mariana; Zhao, Lin; Iwanaga, Ritsuko; Bradford, Andrew P; Kurayoshi, Kenta; Araki, Keigo; Ohtani, Kiyoshi

Distinct E2F-mediated transcriptional program regulates p14ARF gene expression

独特的E2F介导的转录程序调控p14ARF基因表达

期刊:EMBO Journal

影响因子:8.3

doi:10.1038/sj.emboj.7600836

Komori, Hideyuki; Enomoto, Mitsuru; Nakamura, Masataka; Iwanaga, Ritsuko; Ohtani, Kiyoshi

Chromobox2 inhibition: a novel activity of alisertib, an aurora A kinase inhibitor.

Chromobox2 抑制：alisertib（一种极光 A 激酶抑制剂）的新活性。

Distinct Regulation of the ARF and TAp73 Tumor Suppressor Genes by the Transcription Factor E2F1 Enables Discrimination of Cancer Cells from Normal Growing Cells

转录因子E2F1对ARF和TAp73肿瘤抑制基因的独特调控作用，使得区分癌细胞和正常生长细胞成为可能。

Utility of Tumor Suppressor E2F Target Gene Promoter Elements to Drive Gene Expression Specifically in Cancer Cells

肿瘤抑制因子E2F靶基因启动子元件在癌细胞中特异性驱动基因表达的应用

Transcriptional Activation Mechanisms and Target Genes of the Oncogene Product Tax of Human T-Cell Leukemia Virus Type 1

人类T细胞白血病病毒1型癌基因产物Tax的转录激活机制和靶基因

The Transcriptional Coactivator DEAD/H Box 5 (DDX5) Gene Is a Target of the Transcription Factor E2F1 Deregulated from the Tumor Suppressor pRB.

转录共激活因子 DEAD/H 盒 5 (DDX5) 基因是转录因子 E2F1 的靶标，而 E2F1 又受到肿瘤抑制因子 pRB 的调控

Combining EHMT and PARP Inhibition: A Strategy to Diminish Therapy-Resistant Ovarian Cancer Tumor Growth while Stimulating Immune Activation.

结合 EHMT 和 PARP 抑制：一种在抑制耐药性卵巢癌肿瘤生长的同时刺激免疫激活的策略

EHMT1/2 Inhibition Promotes Regression of Therapy-Resistant Ovarian Cancer Tumors in a CD8 T-cell-Dependent Manner.

EHMT1/2 抑制以 CD8 T 细胞依赖的方式促进耐药性卵巢癌肿瘤的消退

Activation of the CDK7 Gene, Coding for the Catalytic Subunit of the Cyclin-Dependent Kinase (CDK)-Activating Kinase (CAK) and General Transcription Factor II H, by the Trans-Activator Protein Tax of Human T-Cell Leukemia Virus Type-1.

人类 T 细胞白血病病毒 1 型的反式激活蛋白 Tax 激活 CDK7 基因，该基因编码细胞周期蛋白依赖性激酶 (CDK) 激活激酶 (CAK) 的催化亚基和通用转录因子 II H

Expanding Roles of the E2F-RB-p53 Pathway in Tumor Suppression

E2F-RB-p53通路在肿瘤抑制中的作用日益增强

Distinct E2F-mediated transcriptional program regulates p14ARF gene expression

独特的E2F介导的转录程序调控p14ARF基因表达