日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Single-Dose Cisplatin Pre-Treatment Enhances Efficacy of ROBO1-Targeted Radioimmunotherapy

单剂量顺铂预处理可增强ROBO1靶向放射免疫疗法的疗效

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms21207728
Fujiwara, Kentaro; Koyama, Keitaro; Tsuji, Atsushi B; Iwanari, Hiroko; Kusano-Arai, Osamu; Higashi, Tatsuya; Momose, Toshimitsu; Hamakubo, Takao
ROBO1
免疫/内分泌
发表日期：2020
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AT2 receptor interacting protein 1 (ATIP1) mediates COX-2 induction by an AT2 receptor agonist in endothelial cells

AT2受体相互作用蛋白1 (ATIP1) 介导AT2受体激动剂在内皮细胞中诱导COX-2的表达。

期刊:Biochemistry and Biophysics Reports
影响因子:2.2
doi:10.1016/j.bbrep.2020.100850
Soda, Keita; Nakada, Yoshiko; Iwanari, Hiroko; Hamakubo, Takao
信号转导
细胞生物学
内皮细胞
发表日期：2020
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Generation of biparatopic antibody through two-step targeting of fragment antibodies on antigen using SpyTag and SpyCatcher

利用 SpyTag 和 SpyCatcher 技术，通过两步法将片段抗体靶向抗原，生成双位点抗体。

期刊:Biotechnology Reports
影响因子:
doi:10.1016/j.btre.2020.e00418
Akiba, Hiroki; Takayanagi, Kensuke; Kusano-Arai, Osamu; Iwanari, Hiroko; Hamakubo, Takao; Tsumoto, Kouhei
发表日期：2020
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The binding property of a monoclonal antibody against the extracellular domains of aquaporin-4 directs aquaporin-4 toward endocytosis

针对水通道蛋白4胞外结构域的单克隆抗体的结合特性引导水通道蛋白4发生内吞作用。

期刊:Biochemistry and Biophysics Reports
影响因子:2.2
doi:10.1016/j.bbrep.2016.05.017
Huang, Ping; Takai, Yoshiki; Kusano-Arai, Osamu; Ramadhanti, Julia; Iwanari, Hiroko; Miyauchi, Takayuki; Sakihama, Toshiko; Han, Jing-Yan; Aoki, Masashi; Hamakubo, Takao; Fujihara, Kazuo; Yasui, Masato; Abe, Yoichiro
单克隆抗体
发表日期：2016
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Structural features of interfacial tyrosine residue in ROBO1 fibronectin domain-antibody complex: Crystallographic, thermodynamic, and molecular dynamic analyses

ROBO1纤连蛋白结构域-抗体复合物中界面酪氨酸残基的结构特征：晶体学、热力学和分子动力学分析

期刊:Protein Science
影响因子:5.2
doi:10.1002/pro.2619
Nakayama, Taisuke; Mizohata, Eiichi; Yamashita, Takefumi; Nagatoishi, Satoru; Nakakido, Makoto; Iwanari, Hiroko; Mochizuki, Yasuhiro; Kado, Yuji; Yokota, Yuki; Satoh, Reiko; Tsumoto, Kouhei; Fujitani, Hideaki; Kodama, Tatsuhiko; Hamakubo, Takao; Inoue, Tsuyoshi
ROBO1
发表日期：2015
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MicroRNA-153 Regulates the Acquisition of Gliogenic Competence by Neural Stem Cells

MicroRNA-153调控神经干细胞获得胶质细胞生成能力

期刊:Stem Cell Reports
影响因子:5.1
doi:10.1016/j.stemcr.2015.06.006
Tsuyama, Jun; Bunt, Jens; Richards, Linda J; Iwanari, Hiroko; Mochizuki, Yasuhiro; Hamakubo, Takao; Shimazaki, Takuya; Okano, Hideyuki
胶质细胞
发育与干细胞
信号转导
干细胞
细胞生物学
发表日期：2015
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90Y-Labeled Anti-ROBO1 Monoclonal Antibody Exhibits Antitumor Activity against Small Cell Lung Cancer Xenografts

90Y标记的抗ROBO1单克隆抗体对小细胞肺癌异种移植瘤表现出抗肿瘤活性

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0125468
Fujiwara, Kentaro; Koyama, Keitaro; Suga, Kosuke; Ikemura, Masako; Saito, Yasutaka; Hino, Akihiro; Iwanari, Hiroko; Kusano-Arai, Osamu; Mitsui, Kenichi; Kasahara, Hiroyuki; Fukayama, Masashi; Kodama, Tatsuhiko; Hamakubo, Takao; Momose, Toshimitsu
单克隆抗体
肺癌
肿瘤
肿瘤免疫
ROBO1
细胞生物学
发表日期：2015
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A (90)Y-labelled anti-ROBO1 monoclonal antibody exhibits antitumour activity against hepatocellular carcinoma xenografts during ROBO1-targeted radioimmunotherapy

一种经 (90)Y 标记的抗 ROBO1 单克隆抗体在 ROBO1 靶向放射免疫治疗中对肝细胞癌异种移植瘤表现出抗肿瘤活性。

期刊:Ejnmmi Research
影响因子:3
doi:10.1186/s13550-014-0029-3
Fujiwara, Kentaro; Koyama, Keitaro; Suga, Kosuke; Ikemura, Masako; Saito, Yasutaka; Hino, Akihiro; Iwanari, Hiroko; Kusano-Arai, Osamu; Mitsui, Kenichi; Kasahara, Hiroyuki; Fukayama, Masashi; Kodama, Tatsuhiko; Hamakubo, Takao; Momose, Toshimitsu
单克隆抗体
肿瘤
肿瘤免疫
ROBO1
细胞生物学
免疫/内分泌
发表日期：2014
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Novel role of copper transport protein antioxidant-1 in neointimal formation after vascular injury

铜转运蛋白抗氧化剂-1在血管损伤后新生内膜形成中的新作用

期刊:Arteriosclerosis Thrombosis and Vascular Biology
影响因子:7.4
doi:10.1161/ATVBAHA.112.300862
Kohno, Takashi; Urao, Norifumi; Ashino, Takashi; Sudhahar, Varadarajan; McKinney, Ronald D; Hamakubo, Takao; Iwanari, Hiroko; Ushio-Fukai, Masuko; Fukai, Tohru
发表日期：2013
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Single chain variable fragment against nicastrin inhibits the gamma-secretase activity.

针对尼卡斯特林的单链可变片段可抑制γ-分泌酶活性

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.M109.055061
Hayashi Ikuo, Takatori Sho, Urano Yasuomi, Iwanari Hiroko, Isoo Noriko, Osawa Satoko, Fukuda Maiko A, Kodama Tatsuhiko, Hamakubo Takao, Li Tong, Wong Philip C, Tomita Taisuke, Iwatsubo Takeshi
信号转导
发表日期：2009
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