Incomplete inhibition of phosphorylation of 4E-BP1 as a mechanism of primary resistance to ATP-competitive mTOR inhibitors
4E-BP1 磷酸化的不完全抑制是 ATP 竞争性 mTOR 抑制剂的主要耐药机制
期刊:Oncogene
影响因子:6.9
doi:10.1038/onc.2013.92
G S Ducker, C E Atreya, J P Simko, Y K Hom, M R Matli, C H Benes, B Hann, E K Nakakura, E K Bergsland, D B Donner, J Settleman, K M Shokat, R S Warren