日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

SARS-CoV-2-specific CD8(+) T cells from people with long COVID establish and maintain effector phenotype and key TCR signatures over 2 years

来自新冠长期患者的 SARS-CoV-2 特异性 CD8(+) T 细胞可在 2 年内建立并维持效应表型和关键 TCR 特征。

Rowntree, Louise C; Audsley, Jennifer; Allen, Lilith F; McQuilten, Hayley A; Hagen, Ruth R; Chaurasia, Priyanka; Petersen, Jan; Littler, Dene R; Tan, Hyon-Xhi; Murdiyarso, Lydia; Habel, Jennifer R; Foo, Isabelle J H; Zhang, Wuji; Ten Berge, Elizabeth R V; Ganesh, Hanujah; Kaewpreedee, Prathanporn; Lee, Kelly W K; Cheng, Samuel M S; Kwok, Janette S Y; Jayasinghe, Dhilshan; Gras, Stephanie; Juno, Jennifer A; Wheatley, Adam K; Kent, Stephen J; Rossjohn, Jamie; Cheng, Allen C; Kotsimbos, Tom C; Trubiano, Jason A; Holmes, Natasha E; Pang Chan, Ken Ka; Hui, David S C; Peiris, Malik; Poon, Leo L M; Lewin, Sharon R; Doherty, Peter C; Thevarajan, Irani; Valkenburg, Sophie A; Kedzierska, Katherine; Nguyen, Thi H O

Quantifying conformational changes in the TCR:pMHC-I binding interface

量化TCR:pMHC-I结合界面构象变化

McMaster, Benjamin; Thorpe, Christopher J; Rossjohn, Jamie; Deane, Charlotte M; Koohy, Hashem

Broad spectrum SARS-CoV-2-specific immunity in hospitalized First Nations peoples recovering from COVID-19

新冠肺炎康复的原住民住院患者体内存在广谱SARS-CoV-2特异性免疫力

Zhang, Wuji; Clemens, E Bridie; Kedzierski, Lukasz; Chua, Brendon Y; Mayo, Mark; Lonzi, Claire; Hinchcliff, Alexandra; Rigas, Vanessa; Middleton, Bianca F; Binks, Paula; Rowntree, Louise C; Allen, Lilith F; Tan, Hyon-Xhi; Petersen, Jan; Chaurasia, Priyanka; Krammer, Florian; Wheatley, Adam K; Kent, Stephen J; Rossjohn, Jamie; Miller, Adrian; Lynar, Sarah; Nelson, Jane; Nguyen, Thi Ho; Davies, Jane; Kedzierska, Katherine

A natural product compound inhibits coronaviral replication in vitro by binding to the conserved Nsp9 SARS-CoV-2 protein

一种天然产物化合物通过与SARS-CoV-2保守的Nsp9蛋白结合,在体外抑制冠状病毒复制。

Littler, Dene R; Liu, Miaomiao; McAuley, Julie L; Lowery, Shea A; Illing, Patricia T; Gully, Benjamin S; Purcell, Anthony W; Chandrashekaran, Indu R; Perlman, Stanley; Purcell, Damian F J; Quinn, Ronald J; Rossjohn, Jamie

Rational design of a hydrolysis-resistant mycobacterial phosphoglycolipid antigen presented by CD1c to T cells

合理设计一种由CD1c呈递给T细胞的耐水解分枝杆菌磷脂糖脂抗原

Reijneveld, Josephine F; Marino, Laura; Cao, Thinh-Phat; Cheng, Tan-Yun; Dam, Dennis; Shahine, Adam; Witte, Martin D; Filippov, Dmitri V; Suliman, Sara; van der Marel, Gijsbert A; Moody, D Branch; Minnaard, Adriaan J; Rossjohn, Jamie; Codée, Jeroen D C; Van Rhijn, Ildiko

SARS-CoV-2-specific CD8(+) T-cell responses and TCR signatures in the context of a prominent HLA-A*24:02 allomorph

在显著的HLA-A*24:02同种异型背景下,SARS-CoV-2特异性CD8(+) T细胞反应和TCR特征

Rowntree, Louise C; Petersen, Jan; Juno, Jennifer A; Chaurasia, Priyanka; Wragg, Kathleen; Koutsakos, Marios; Hensen, Luca; Wheatley, Adam K; Kent, Stephen J; Rossjohn, Jamie; Kedzierska, Katherine; Nguyen, Thi Ho

Challenging immunodominance of influenza-specific CD8+ T cell responses restricted by the risk-associated HLA-A*68:01 allomorph

挑战由风险相关的HLA-A*68:01同种异型体限制的流感特异性CD8+ T细胞反应的免疫优势

C E van de Sandt ,E B Clemens ,E J Grant ,L C Rowntree ,S Sant ,H Halim ,J Crowe ,A C Cheng ,T C Kotsimbos ,M Richards ,A Miller ,S Y C Tong ,J Rossjohn ,T H O Nguyen ,S Gras ,W Chen ,K Kedzierska

Mucosal-associated invariant T-cell activation and accumulation after in vivo infection depends on microbial riboflavin synthesis and co-stimulatory signals

体内感染后粘膜相关不变T细胞的活化和积累依赖于微生物核黄素的合成和共刺激信号

Z Chen, H Wang, C D'Souza, S Sun, L Kostenko, S B G Eckle, B S Meehan, D C Jackson, R A Strugnell, H Cao, N Wang, D P Fairlie, L Liu, D I Godfrey, J Rossjohn, J McCluskey, A J Corbett

A semi-invariant Vα10+ T cell antigen receptor defines a population of natural killer T cells with distinct glycolipid antigen-recognition properties

一种半不变的Vα10+ T细胞抗原受体定义了一类具有独特糖脂抗原识别特性的自然杀伤T细胞。

Uldrich, Adam P; Patel, Onisha; Cameron, Garth; Pellicci, Daniel G; Day, E Bridie; Sullivan, Lucy C; Kyparissoudis, Konstantinos; Kjer-Nielsen, Lars; Vivian, Julian P; Cao, Benjamin; Brooks, Andrew G; Williams, Spencer J; Illarionov, Petr; Besra, Gurdyal S; Turner, Stephen J; Porcelli, Steven A; McCluskey, James; Smyth, Mark J; Rossjohn, Jamie; Godfrey, Dale I

Constraints within major histocompatibility complex class I restricted peptides: presentation and consequences for T-cell recognition

主要组织相容性复合体I类限制性肽的限制:呈递及其对T细胞识别的影响

Theodossis, Alex; Guillonneau, Carole; Welland, Andrew; Ely, Lauren K; Clements, Craig S; Williamson, Nicholas A; Webb, Andrew I; Wilce, Jacqueline A; Mulder, Roger J; Dunstone, Michelle A; Doherty, Peter C; McCluskey, James; Purcell, Anthony W; Turner, Stephen J; Rossjohn, Jamie