日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structural and evolutionary constraints of organophosphate resistance in dipteran carboxylesterases

双翅目羧酸酯酶中有机磷抗性的结构和进化限制

Frkic, Rebecca L; Giang, Alex; Pulsford, Sacha B; Liu, Jian-Wei; Esmaeily, Mojtaba; Carr, Paul D; Fraser, Nicholas J; Hopkins, Davis; Oakeshott, John G; Batterham, Philip; Mabbitt, Peter D; Jackson, Colin J

Fragment Screening and Structure-Guided Development of Heparanase Inhibitors Reveal Orthosteric and Allosteric Inhibition

肝素酶抑制剂的片段筛选和结构导向开发揭示了正构和变构抑制作用

Davies, Lani J; Whitefield, Cassidy; Kim, Hyunjin; Nitsche, Christoph; Jackson, Colin J; Frkic, Rebecca L

Ancestral reconstruction of polyethylene terephthalate degrading cutinases reveals a rugged and unexplored sequence-fitness landscape

聚对苯二甲酸乙二醇酯降解角质酶的祖先重建揭示了一个崎岖且尚未探索的序列适应性图景

Vongsouthi, Vanessa; Georgelin, Rosemary; Matthews, Dana S; Saunders, Jake; Lee, Brendon M; Ton, Jennifer; Damry, Adam M; Frkic, Rebecca L; Spence, Matthew A; Jackson, Colin J

An increased copy number of glycine decarboxylase (GLDC) associated with psychosis reduces extracellular glycine and impairs NMDA receptor function

精神病患者体内甘氨酸脱羧酶 (GLDC) 拷贝数增加,导致细胞外甘氨酸水平降低,并损害 NMDA 受体功能。

Kambali, Maltesh; Li, Yan; Unichenko, Petr; Feria Pliego, Jessica A; Yadav, Rachita; Liu, Jing; McGuinness, Patrick; Cobb, Johanna G; Wang, Muxiao; Nagarajan, Rajasekar; Lyu, Jinrui; Vongsouthi, Vanessa; Jackson, Colin J; Engin, Elif; Coyle, Joseph T; Shin, Jaeweon; Hodgson, Nathaniel W; Hensch, Takao K; Talkowski, Michael E; Homanics, Gregg E; Bolshakov, Vadim Y; Henneberger, Christian; Rudolph, Uwe

Exploring Large Protein Sequence Space through Homology- and Representation-based Hierarchical Clustering

通过基于同源性和表征的层次聚类探索大型蛋白质序列空间

Chen, John Z; Gall, Barnabas; Pulsford, Sacha B; Tokuriki, Nobuhiko; Jackson, Colin J

Expanding the biocatalytic and oxidative landscape of the old yellow enzyme family

拓展古老黄酶家族的生物催化和氧化作用范围

White, David W; Frkic, Rebecca L; Iamurri, Samantha; Keshavarz-Joud, Parisa; Blue, Tamra; Jackson, Colin J; Copp, Janine; Lutz, Stefan

Isolation, identification, and characterisation of the malachite green detoxifying bacterial strain Bacillus pacificus ROC1 and the azoreductase AzrC

分离、鉴定和表征孔雀石绿解毒细菌菌株太平洋芽孢杆菌ROC1及其偶氮还原酶AzrC

Bibi, Shanza; Breeze, Callum W; Jadoon, Vusqa; Fareed, Anum; Syed, Alina; Frkic, Rebecca L; Zaffar, Habiba; Ali, Muhammad; Zeb, Iftikhar; Jackson, Colin J; Naqvi, Tatheer Alam

A Thermostable Bacterial Metallohydrolase that Degrades Organophosphate Plasticizers

一种能降解有机磷酸酯增塑剂的耐热细菌金属水解酶

Ji, Dawei; Frkic, Rebecca L; Delyami, Javad; Larsen, Joachim S; Spence, Matthew A; Jackson, Colin J

The ultra-high affinity transport proteins of ubiquitous marine bacteria

普遍存在的海洋细菌的超高亲和力转运蛋白

Clifton, Ben E; Alcolombri, Uria; Uechi, Gen-Ichiro; Jackson, Colin J; Laurino, Paola

Rugged fitness landscapes minimize promiscuity in the evolution of transcriptional repressors.

崎岖的适应性地形最大限度地减少了转录抑制因子进化过程中的混杂性

Meger Anthony T, Spence Matthew A, Sandhu Mahakaran, Matthews Dana, Chen Jackie, Jackson Colin J, Raman Srivatsan