日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Correction: Intracellular trafficking SNARE protein, syntaxin-6, modifies prion cellular phenotypes and risk of disease development in vivo

更正:细胞内转运SNARE蛋白syntaxin-6可改变朊病毒的细胞表型并影响体内疾病发生的风险。

Hill, Elizabeth; Patel, Mitali M; Ribes, Juan M; Linehan, Jacqueline; Zhang, Fuquan; Jakubcova, Tatiana; Hamdan, Shyma; Tomlinson, Andrew; Ercolani, Tiziana; Schmidt, Christian; Ahmed, Parvin; Thirlway, George; Argentina, Fabio; Marinho, Aline T; Jones, Emma; Kaye, Nicholas; Fitzhugh, Craig; Jackson, Graham S; Brandner, Sebastian; Klöhn, Peter-Christian; Collinge, John; Cunningham, Thomas J; Mead, Simon

Intracellular trafficking SNARE protein, syntaxin-6, modifies prion cellular phenotypes and risk of disease development in vivo

细胞内转运SNARE蛋白syntaxin-6可改变朊病毒的细胞表型,并影响体内疾病发生的风险。

Hill, Elizabeth; Patel, Mitali M; Ribes, Juan M; Linehan, Jacqueline; Zhang, Fuquan; Jakubcova, Tatiana; Hamdan, Shyma; Tomlinson, Andrew; Ercolani, Tiziana; Schmidt, Christian; Ahmed, Parvin; Thirlway, George; Argentina, Fabio; Marinho, Aline T; Jones, Emma; Kaye, Nicholas; Fitzhugh, Craig; Jackson, Graham S; Brandner, Sebastian; Klöhn, Peter-Christian; Collinge, John; Cunningham, Thomas J; Mead, Simon

Essential Components of Synthetic Infectious Prion Formation De Novo

从头合成感染性朊病毒形成的基本组成部分

Jack, Kezia; Jackson, Graham S; Bieschke, Jan

Overexpression of mouse prion protein in transgenic mice causes a non-transmissible spongiform encephalopathy

转基因小鼠体内小鼠朊病毒蛋白的过度表达会导致一种非传染性海绵状脑病。

Jackson, Graham S; Linehan, Jacqueline; Brandner, Sebastian; Asante, Emmanuel A; Wadsworth, Jonathan D F; Collinge, John

Evaluation of plasma tau and neurofilament light chain biomarkers in a 12-year clinical cohort of human prion diseases

对人类朊病毒疾病12年临床队列中血浆tau蛋白和神经丝轻链生物标志物的评估

Thompson, Andrew G B; Anastasiadis, Prodromos; Druyeh, Ronald; Whitworth, Ines; Nayak, Annapurna; Nihat, Akin; Mok, Tze How; Rudge, Peter; Wadsworth, Jonathan D F; Rohrer, Jonathan; Schott, Jonathan M; Heslegrave, Amanda; Zetterberg, Henrik; Collinge, John; Jackson, Graham S; Mead, Simon

Bank vole prion protein extends the use of RT-QuIC assays to detect prions in a range of inherited prion diseases

田鼠朊病毒蛋白拓展了RT-QuIC检测方法在多种遗传性朊病毒疾病中检测朊病毒的应用范围。

Mok, Tze How; Nihat, Akin; Luk, Connie; Sequeira, Danielle; Batchelor, Mark; Mead, Simon; Collinge, John; Jackson, Graham S

Structural effects of the highly protective V127 polymorphism on human prion protein.

高度保护性的 V127 多态性对人类朊病毒蛋白的结构影响

Hosszu Laszlo L P, Conners Rebecca, Sangar Daljit, Batchelor Mark, Sawyer Elizabeth B, Fisher Stuart, Cliff Matthew J, Hounslow Andrea M, McAuley Katherine, Leo Brady R, Jackson Graham S, Bieschke Jan, Waltho Jonathan P, Collinge John

Neurofilament light chain and tau concentrations are markedly increased in the serum of patients with sporadic Creutzfeldt-Jakob disease, and tau correlates with rate of disease progression

散发型克雅氏病患者血清中神经丝轻链和tau蛋白浓度显著升高,且tau蛋白水平与疾病进展速度相关。

Thompson, Andrew Geoffrey Bourne; Luk, Connie; Heslegrave, Amanda J; Zetterberg, Henrik; Mead, Simon H; Collinge, John; Jackson, Graham S

Diagnosing Sporadic Creutzfeldt-Jakob Disease by the Detection of Abnormal Prion Protein in Patient Urine

通过检测患者尿液中异常朊病毒蛋白诊断散发型克雅氏病

Luk, Connie; Jones, Samantha; Thomas, Claire; Fox, Nick C; Mok, Tze H; Mead, Simon; Collinge, John; Jackson, Graham S

Physical, chemical and kinetic factors affecting prion infectivity

影响朊病毒感染性的物理、化学和动力学因素

Properzi, Francesca; Badhan, Anjna; Klier, Steffi; Schmidt, Christian; Klöhn, Peter C; Wadsworth, Jonathan D F; Clarke, Anthony R; Jackson, Graham S; Collinge, John