Jackson Mandy相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Effectiveness of Benralizumab in Reducing Asthma and COPD Exacerbations in Patients with Severe Asthma and Concomitant COPD: Real-World Evidence from the ZEPHYR-5 Study

贝那利珠单抗在降低重度哮喘合并慢性阻塞性肺疾病患者哮喘和慢性阻塞性肺疾病急性加重方面的疗效：来自 ZEPHYR-5 研究的真实世界证据

期刊:International Journal of Chronic Obstructive Pulmonary Disease

影响因子:3.1

doi:10.2147/COPD.S562498

Adrish, Muhammad; DeMartino, Jessica K; Carstens, Donna; Jackson, Mandy; Wilson, Kathleen; Schinkel, Jill; Tkacz, Joseph

慢性阻塞性肺疾病

发表日期：2026

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Benralizumab Reduces Asthma Exacerbations and Costs Among Medicare Beneficiaries with Severe Asthma: The ZEPHYR-5 Study

贝那利珠单抗可降低重度哮喘患者（Medicare受益人）的哮喘急性发作次数和治疗费用：ZEPHYR-5研究

期刊:Journal of Asthma and Allergy

doi:10.2147/JAA.S568990

Adrish, Muhammad; DeMartino, Jessica K; Carstens, Donna; Jackson, Mandy; Schinkel, Jill; Wilson, Kathleen; Tkacz, Joseph

发表日期：2026

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Automated gait analysis indicates efficacy of T-type calcium channel inhibition for mitigation of disrupted calcium signalling in an SCA5 mouse model.

自动步态分析表明，T 型钙通道抑制剂可有效缓解 SCA5 小鼠模型中钙信号传导紊乱

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-025-05511-1

Suminaite Daumante, Talib Nurul Fatihah, Pettegree Sophie Jane, Tan Han Chew Gaelan, Odey Yvonne Louise, Perkins Emma Margaret, Lyndon Alastair Robert, Skehel Paul Andrew, Jackson Mandy

发表日期：2025

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Loss of cerebellar glutamate transporters EAAT4 and GLAST differentially affects the spontaneous firing pattern and survival of Purkinje cells

小脑谷氨酸转运蛋白EAAT4和GLAST的缺失对浦肯野细胞的自发放电模式和存活率产生不同的影响。

期刊:Human Molecular Genetics

影响因子:3.2

doi:10.1093/hmg/ddy169

Perkins, Emma M; Clarkson, Yvonne L; Suminaite, Daumante; Lyndon, Alastair R; Tanaka, Kohichi; Rothstein, Jeffrey D; Skehel, Paul A; Wyllie, David J A; Jackson, Mandy

细胞生物学

发表日期：2018

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Posterior cerebellar Purkinje cells in an SCA5/SPARCA1 mouse model are especially vulnerable to the synergistic effect of loss of β-III spectrin and GLAST

在SCA5/SPARCA1小鼠模型中，小脑后部浦肯野细胞对β-III谱蛋白和GLAST缺失的协同作用尤为敏感。

期刊:Human Molecular Genetics

影响因子:3.2

doi:10.1093/hmg/ddw274

Perkins, Emma M; Suminaite, Daumante; Clarkson, Yvonne L; Lee, Sin Kwan; Lyndon, Alastair R; Rothstein, Jeffrey D; Wyllie, David J A; Tanaka, Kohichi; Jackson, Mandy

细胞生物学

发表日期：2016

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De novo point mutations in patients diagnosed with ataxic cerebral palsy

共济失调型脑瘫患者的新生点突变

影响因子:11.7

doi:10.1093/brain/awv117

Parolin Schnekenberg, Ricardo; Perkins, Emma M; Miller, Jack W; Davies, Wayne I L; D'Adamo, Maria Cristina; Pessia, Mauro; Fawcett, Katherine A; Sims, David; Gillard, Elodie; Hudspith, Karl; Skehel, Paul; Williams, Jonathan; O'Regan, Mary; Jayawant, Sandeep; Jefferson, Rosalind; Hughes, Sarah; Lustenberger, Andrea; Ragoussis, Jiannis; Jackson, Mandy; Tucker, Stephen J; Németh, Andrea H

发表日期：2015

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β-III spectrin underpins ankyrin R function in Purkinje cell dendritic trees: protein complex critical for sodium channel activity is impaired by SCA5-associated mutations

β-III 血影蛋白是浦肯野细胞树突中锚蛋白 R 功能的基础：对钠通道活性至关重要的蛋白质复合物会因 SCA5 相关突变而受损

期刊:Human Molecular Genetics

影响因子:3.2

doi:10.1093/hmg/ddu103

Clarkson, Yvonne L; Perkins, Emma M; Cairncross, Callum J; Lyndon, Alastair R; Skehel, Paul A; Jackson, Mandy

细胞生物学

发表日期：2014

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Recessive mutations in SPTBN2 implicate β-III spectrin in both cognitive and motor development

SPTBN2基因的隐性突变与β-III谱蛋白在认知和运动发育中均有关联。

期刊:PLoS Genetics

影响因子:3.7

doi:10.1371/journal.pgen.1003074

Lise, Stefano; Clarkson, Yvonne; Perkins, Emma; Kwasniewska, Alexandra; Sadighi Akha, Elham; Schnekenberg, Ricardo Parolin; Suminaite, Daumante; Hope, Jilly; Baker, Ian; Gregory, Lorna; Green, Angie; Allan, Chris; Lamble, Sarah; Jayawant, Sandeep; Quaghebeur, Gerardine; Cader, M Zameel; Hughes, Sarah; Armstrong, Richard J E; Kanapin, Alexander; Rimmer, Andrew; Lunter, Gerton; Mathieson, Iain; Cazier, Jean-Baptiste; Buck, David; Taylor, Jenny C; Bentley, David; McVean, Gilean; Donnelly, Peter; Knight, Samantha J L; Jackson, Mandy; Ragoussis, Jiannis; Németh, Andrea H

发育与干细胞

发表日期：2012

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Combining comparative proteomics and molecular genetics uncovers regulators of synaptic and axonal stability and degeneration in vivo

结合比较蛋白质组学和分子遗传学，揭示了体内突触和轴突稳定性及退化的调控因子。

期刊:PLoS Genetics

影响因子:3.7

doi:10.1371/journal.pgen.1002936

Wishart, Thomas M; Rooney, Timothy M; Lamont, Douglas J; Wright, Ann K; Morton, A Jennifer; Jackson, Mandy; Freeman, Marc R; Gillingwater, Thomas H

发表日期：2012

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Beta-III spectrin mutation L253P associated with spinocerebellar ataxia type 5 interferes with binding to Arp1 and protein trafficking from the Golgi

与5型脊髓小脑性共济失调相关的β-III谱蛋白L253P突变会干扰其与Arp1的结合以及蛋白质从高尔基体的转运。

期刊:Human Molecular Genetics

影响因子:3.2

doi:10.1093/hmg/ddq279

Clarkson, Yvonne L; Gillespie, Trudi; Perkins, Emma M; Lyndon, Alastair R; Jackson, Mandy

发表日期：2010

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