日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Reduction of spermine synthase enhances autophagy to suppress Tau accumulation

精胺合酶减少可增强自噬,从而抑制 Tau 积累

Xianzun Tao, Jiaqi Liu, Zoraida Diaz-Perez, Jackson R Foley, Ashley Nwafor, Tracy Murray Stewart, Robert A Casero Jr, R Grace Zhai

Impaired polyamine metabolism causes behavioral and neuroanatomical defects in a mouse model of Snyder-Robinson syndrome

多胺代谢受损导致 Snyder-Robinson 综合征小鼠模型出现行为和神经解剖学缺陷

Oluwaseun Akinyele, Anushe Munir, Marie A Johnson, Megan S Perez, Yuan Gao, Jackson R Foley, Ashley Nwafor, Yijen Wu, Tracy Murray-Stewart, Robert A Casero Jr, Hülya Bayir, Dwi U Kemaladewi

Polyamine Catabolism and Its Role in Renal Injury and Fibrosis in Mice Subjected to Repeated Low-Dose Cisplatin Treatment

多胺分解代谢及其在重复低剂量顺铂治疗小鼠肾损伤和纤维化中的作用

Kamyar Zahedi, Sharon Barone, Marybeth Brooks, Tracy Murray Stewart, Jackson R Foley, Ashley Nwafor, Robert A Casero Jr, Manoocher Soleimani

Deoxyhypusine synthase mutations alter the post-translational modification of eukaryotic initiation factor 5A resulting in impaired human and mouse neural homeostasis

脱氧脯氨酸合酶突变会改变真核起始因子 5A 的翻译后修饰,导致人类和小鼠神经稳态受损

Leah R Padgett, Mollie R Shinkle, Spencer Rosario, Tracy Murray Stewart, Jackson R Foley, Robert A Casero Jr, Myung Hee Park, Wendy K Chung, Teresa L Mastracci

Functional assessment of homozygous ALDH18A1 variants reveals alterations in amino acid and antioxidant metabolism

纯合 ALDH18A1 变异的功能评估揭示了氨基酸和抗氧化剂代谢的改变

Maxwell B Colonna, Tonya Moss, Sneha Mokashi, Sujata Srikanth, Julie R Jones, Jackson R Foley, Cindy Skinner, Angie Lichty, Anthony Kocur, Tim Wood, Tracy Murray Stewart, Robert A Casero Jr, Heather Flanagan-Steet, Arthur S Edison, Michael J Lyons, Richard Steet

Reduction of Spermine Synthase Suppresses Tau Accumulation Through Autophagy Modulation in Tauopathy

精胺合酶的减少通过 Tau 蛋白病中的自噬调节抑制 Tau 蛋白的积累

Xianzun Tao, Jiaqi Liu, Zoraida Diaz-Perez, Jackson R Foley, Tracy Murray Stewart, Robert A Casero Jr, R Grace Zhai

Impaired polyamine metabolism causes behavioral and neuroanatomical defects in a novel mouse model of Snyder-Robinson Syndrome

多胺代谢受损导致新型 Snyder-Robinson 综合征小鼠出现行为和神经解剖学缺陷

Oluwaseun Akinyele, Anushe Munir, Marie A Johnson, Megan S Perez, Yuan Gao, Jackson R Foley, Yijen Wu, Tracy Murray-Stewart, Robert A Casero Jr, Hulya Bayir, Dwi U Kemaladewi

Phenylbutyrate modulates polyamine acetylase and ameliorates Snyder-Robinson syndrome in a Drosophila model and patient cells

苯丁酸酯可调节多胺乙酰化酶,并在果蝇模型和患者细胞中改善斯奈德-罗宾逊综合征。

Xianzun Tao ,Yi Zhu ,Zoraida Diaz-Perez ,Seok-Ho Yu ,Jackson R Foley ,Tracy Murray Stewart ,Robert A Casero Jr ,Richard Steet ,R Grace Zhai

Self-Assembled Alkylated Polyamine Analogs as Supramolecular Anticancer Agents

自组装烷基化多胺类似物作为超分子抗癌剂

Diptesh Sil, Sudipta Panja, Chinmay M Jogdeo, Raj Kumar, Ao Yu, Cassandra E Holbert, Ling Ding, Jackson R Foley, Tracy Murray Stewart, Robert A Casero Jr, David Oupický

Histone deacetylase-10 liberates spermidine to support polyamine homeostasis and tumor cell growth

组蛋白去乙酰化酶-10 释放亚精胺以维持多胺稳态和肿瘤细胞生长

Tracy Murray Stewart, Jackson R Foley, Cassandra E Holbert, Glynis Klinke, Gernot Poschet, Raphael R Steimbach, Aubry K Miller, Robert A Casero Jr