日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Paving the way toward treatment solutions for CTNNB1 syndrome: a patient organization perspective

为CTNNB1综合征的治疗方案铺平道路:患者组织的视角

Miroševič, Špela; Khandelwal, Shivang; Amerson, Emily; Parks, Effie; Parks, Mariana; Cochran, Lauren; González Hernández, Ana; Ferraro, Mirela; Lisowski, Leszek; Perez-Iturralde, Andrea; Chung, Wendy; Jacob, Michele H; Žakelj, Nina; Lainšček, Duško; Forstnerič, Vida; Sušjan, Petra; Maruna, Matea; Jerala, Roman; Osredkar, Damjan

Excessive β-Catenin in Excitatory Neurons Results in Reduced Social and Increased Repetitive Behaviors and Altered Expression of Multiple Genes Linked to Human Autism

兴奋性神经元中β-catenin过量会导致社交能力下降、重复行为增多,并改变与人类自闭症相关的多个基因的表达。

Alexander, Jonathan Michael; Pirone, Antonella; Jacob, Michele H

Learning impairments and molecular changes in the brain caused by β-catenin loss

β-catenin缺失导致的学习障碍和大脑分子变化

Wickham, Robert J; Alexander, Jonathan M; Eden, Lillian W; Valencia-Yang, Mabel; Llamas, Josué; Aubrey, John R; Jacob, Michele H

Extracellular matrix directs phenotypic heterogeneity of activated fibroblasts.

细胞外基质决定活化成纤维细胞的表型异质性

Avery Diana, Govindaraju Priya, Jacob Michele, Todd Leslie, Monslow James, Puré Ellen

Social Stimulus Causes Aberrant Activation of the Medial Prefrontal Cortex in a Mouse Model With Autism-Like Behaviors

社会刺激导致具有自闭症样行为的小鼠模型内侧前额叶皮层异常激活

Pirone, Antonella; Alexander, Jonathan M; Koenig, Jenny B; Cook-Snyder, Denise R; Palnati, Medha; Wickham, Robert J; Eden, Lillian; Shrestha, Neha; Reijmers, Leon; Biederer, Thomas; Miczek, Klaus A; Dulla, Chris G; Jacob, Michele H

APC conditional knock-out mouse is a model of infantile spasms with elevated neuronal β-catenin levels, neonatal spasms, and chronic seizures

APC条件性敲除小鼠是婴儿痉挛症的模型,其特征是神经元β-catenin水平升高、新生儿痉挛和慢性癫痫发作。

Pirone, Antonella; Alexander, Jonathan; Lau, Lauren A; Hampton, David; Zayachkivsky, Andrew; Yee, Amy; Yee, Audrey; Jacob, Michele H; Dulla, Chris G

Alexa Fluor 546-ArIB[V11L;V16A] is a potent ligand for selectively labeling alpha 7 nicotinic acetylcholine receptors

Alexa Fluor 546-ArIB[V11L;V16A] 是一种强效配体,可选择性地标记 α7 尼古丁乙酰胆碱受体。

Hone, Arik J; Whiteaker, Paul; Mohn, Jesse L; Jacob, Michele H; McIntosh, J Michael

Dystrophin and utrophin isoforms are expressed in glia, but not neurons, of the avian parasympathetic ciliary ganglion

肌营养不良蛋白和肌营养不良蛋白亚型在鸟类副交感神经睫状神经节的神经胶质细胞中表达,但不在神经元中表达。

Blitzblau, Rachel; Storer, Elizabeth K; Jacob, Michele H

RGS3 mediates a calcium-dependent termination of G protein signaling in sensory neurons

RGS3介导感觉神经元中G蛋白信号传导的钙依赖性终止

Tosetti, Patrizia; Pathak, Narendra; Jacob, Michele H; Dunlap, Kathleen

Extrasynaptic alpha 7-nicotinic acetylcholine receptor expression in developing neurons is regulated by inputs, targets, and activity

发育中神经元的突触外α7-尼古丁乙酰胆碱受体表达受输入、靶点和活动调控。

Brumwell, Craig L; Johnson, James L; Jacob, Michele H