Focal radiation therapy combined with 4-1BB activation and CTLA-4 blockade yields long-term survival and a protective antigen-specific memory response in a murine glioma model
在小鼠胶质瘤模型中,局部放射治疗联合 4-1BB 激活和 CTLA-4 阻断可实现长期生存和保护性抗原特异性记忆反应。
期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0101764
Belcaid, Zineb; Phallen, Jillian A; Zeng, Jing; See, Alfred P; Mathios, Dimitrios; Gottschalk, Chelsea; Nicholas, Sarah; Kellett, Meghan; Ruzevick, Jacob; Jackson, Christopher; Albesiano, Emilia; Durham, Nicholas M; Ye, Xiaobu; Tran, Phuoc T; Tyler, Betty; Wong, John W; Brem, Henry; Pardoll, Drew M; Drake, Charles G; Lim, Michael