日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
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2025
2026
影响因子:
–

A versatile, high-efficiency platform for CRISPR-based gene activation

一种用途广泛、高效的基于 CRISPR 的基因激活平台

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-023-36452-w
Heidersbach, Amy J; Dorighi, Kristel M; Gomez, Javier A; Jacobi, Ashley M; Haley, Benjamin
发表日期：2023
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CRISPAltRations: a validated cloud-based approach for interrogation of double-strand break repair mediated by CRISPR genome editing

CRISPAltRations：一种经过验证的基于云的方法，用于研究 CRISPR 基因组编辑介导的双链断裂修复。

期刊:Molecular Therapy-Methods & Clinical Development
影响因子:4.7
doi:10.1016/j.omtm.2021.03.024
Kurgan, Gavin; Turk, Rolf; Li, Heng; Roberts, Nathan; Rettig, Garrett R; Jacobi, Ashley M; Tso, Lauren; Sturgeon, Morgan; Mertens, Massimo; Noten, Roel; Florus, Kurt; Behlke, Mark A; Wang, Yu; McNeill, Matthew S
发表日期：2021
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Highly Efficient CRISPR-Cas9-Based Methods for Generating Deletion Mutations and F0 Embryos that Lack Gene Function in Zebrafish.

利用 CRISPR-Cas9 技术高效生成斑马鱼缺失突变体和缺乏基因功能的 F0 胚胎的方法

期刊:Developmental Cell
影响因子:8.7
doi:10.1016/j.devcel.2019.10.004
Hoshijima Kazuyuki, Jurynec Michael J, Klatt Shaw Dana, Jacobi Ashley M, Behlke Mark A, Grunwald David Jonah
发表日期：2019
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Functional inhibition of chemokine receptor CCR2 by dicer-substrate-siRNA prevents pain development

利用Dicer底物siRNA对趋化因子受体CCR2进行功能性抑制可预防疼痛的发生。

期刊:Molecular Pain
影响因子:2.8
doi:10.1177/1744806916653969
Bégin-Lavallée, Valérie; Midavaine, Élora; Dansereau, Marc-André; Tétreault, Pascal; Longpré, Jean-Michel; Jacobi, Ashley M; Rose, Scott D; Behlke, Mark A; Beaudet, Nicolas; Sarret, Philippe
CR2
信号转导
免疫/内分泌
发表日期：2016
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Correlating In Vitro Splice Switching Activity With Systemic In Vivo Delivery Using Novel ZEN-modified Oligonucleotides

利用新型ZEN修饰寡核苷酸，将体外剪接转换活性与体内系统递送相关联

期刊:Molecular Therapy-Nucleic Acids
影响因子:6.1
doi:10.1038/mtna.2014.63
Hammond, Suzan M; McClorey, Graham; Nordin, Joel Z; Godfrey, Caroline; Stenler, Sofia; Lennox, Kim A; Smith, C I Edvard; Jacobi, Ashley M; Varela, Miguel A; Lee, Yi; Behlke, Mark A; Wood, Matthew J A; Andaloussi, Samir E L
发表日期：2014
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Inosine-mediated modulation of RNA sensing by Toll-like receptor 7 (TLR7) and TLR8

肌苷介导的 Toll 样受体 7 (TLR7) 和 TLR8 对 RNA 感应的调节

期刊:Journal of Virology
影响因子:3.8
doi:10.1128/JVI.01571-13
Sarvestani, Soroush T; Tate, Michelle D; Moffat, Jessica M; Jacobi, Ashley M; Behlke, Mark A; Miller, Alistair R; Beckham, Simone A; McCoy, Claire E; Chen, Weisan; Mintern, Justine D; O'Keeffe, Meredith; John, Matthias; Williams, Bryan R G; Gantier, Michael P
信号转导
TLR7
发表日期：2014
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Post-transcriptional regulation of cystic fibrosis transmembrane conductance regulator expression and function by microRNAs

微RNA对囊性纤维化跨膜传导调节因子表达和功能的转录后调控

期刊:American Journal of Respiratory Cell and Molecular Biology
影响因子:5.3
doi:10.1165/rcmb.2012-0430OC
Ramachandran, Shyam; Karp, Philip H; Osterhaus, Samantha R; Jiang, Peng; Wohlford-Lenane, Christine; Lennox, Kim A; Jacobi, Ashley M; Praekh, Kal; Rose, Scott D; Behlke, Mark A; Xing, Yi; Welsh, Michael J; McCray, Paul B Jr
信号转导
发表日期：2013
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A microRNA network regulates expression and biosynthesis of wild-type and DeltaF508 mutant cystic fibrosis transmembrane conductance regulator

微RNA网络调控野生型和ΔF508突变型囊性纤维化跨膜传导调节因子的表达和生物合成。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1210906109
Ramachandran, Shyam; Karp, Philip H; Jiang, Peng; Ostedgaard, Lynda S; Walz, Amy E; Fisher, John T; Keshavjee, Shaf; Lennox, Kim A; Jacobi, Ashley M; Rose, Scott D; Behlke, Mark A; Welsh, Michael J; Xing, Yi; McCray, Paul B Jr
信号转导
发表日期：2012
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