日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Utility of physiologically based pharmacokinetic modeling to predict inter-antibody variability in monoclonal antibody pharmacokinetics in mice

利用生理药代动力学模型预测小鼠单克隆抗体药代动力学中抗体间差异的效用

Liu, Shufang; Humphreys, Sara C; Cook, Kevin D; Conner, Kip P; Correia, Ana R; Jacobitz, Alex W; Yang, Melissa; Primack, Ronya; Soto, Marcus; Padaki, Rupa; Lubomirski, Mariusz; Smith, Richard; Mock, Marissa; Thomas, Veena A

Development of in silico models to predict viscosity and mouse clearance using a comprehensive analytical data set collected on 83 scaffold-consistent monoclonal antibodies

使用收集的 83 种支架一致的单克隆抗体的综合分析数据集开发计算机模型来预测粘度和小鼠清除率

Marissa Mock, Alex W Jacobitz, Christopher James Langmead, Athena Sudom, Daniel Yoo, Sara C Humphreys, Mai Alday, Larysa Alekseychyk, Nicolas Angell, Vivian Bi, Hannah Catterall, Chen-Chun Chen, Hui-Ting Chou, Kip P Conner, Kevin D Cook, Ana R Correia, Andrew Dykstra, Sudipa Ghimire-Rijal, Kevin Gra

Sortase Transpeptidases: Structural Biology and Catalytic Mechanism

分选转肽酶:结构生物学和催化机制

Jacobitz, Alex W; Kattke, Michele D; Wereszczynski, Jeff; Clubb, Robert T

Rapid addition of unlabeled silent solubility tags to proteins using a new substrate-fused sortase reagent

利用新型底物融合分选酶试剂,可快速将未标记的沉默溶解度标签添加到蛋白质上。

Amer, Brendan R; Macdonald, Ramsay; Jacobitz, Alex W; Liauw, Brandon; Clubb, Robert T

Solution structure of the sortase required for efficient production of infectious Bacillus anthracis spores

高效产生感染性炭疽芽孢杆菌孢子所需的分选酶的溶液结构

Robson, Scott A; Jacobitz, Alex W; Phillips, Martin L; Clubb, Robert T

Removal of CO dehydrogenase from Pseudomonas carboxydovorans cytoplasmic membranes, rebinding of CO dehydrogenase to depleted membranes, and restoration of respiratory activities

从羧基假单胞菌细胞质膜上去除CO脱氢酶,将CO脱氢酶重新结合到已耗竭的膜上,并恢复呼吸活性

Jacobitz, S; Meyer, O