日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Combination therapy of a PSEN1-selective γ-secretase inhibitor with dexamethasone and an XPO1 inhibitor to target T-cell acute lymphoblastic leukemia

PSEN1选择性γ-分泌酶抑制剂联合地塞米松和XPO1抑制剂治疗T细胞急性淋巴细胞白血病

Vandersmissen, Charlien; Prieto, Cristina; Gielen, Olga; Jacobs, Kris; Nittner, David; Maertens, Johan; Segers, Heidi; Cools, Jan

Aberrant MYCN expression drives oncogenic hijacking of EZH2 as a transcriptional activator in peripheral T-cell lymphoma

异常的MYCN表达驱动EZH2作为转录激活因子在周围T细胞淋巴瘤中发生致癌劫持

Vanden Bempt, Marlies; Debackere, Koen; Demeyer, Sofie; Van Thillo, Quentin; Meeuws, Nienke; Prieto, Cristina; Provost, Sarah; Mentens, Nicole; Jacobs, Kris; Gielen, Olga; Nittner, David; Ogawa, Seishi; Kataoka, Keisuke; Graux, Carlos; Tousseyn, Thomas; Cools, Jan; Dierickx, Daan

Oncogenic Cooperation Between IL7R-JAK-STAT Pathway Mutations

IL7R-JAK-STAT通路突变之间的致癌协同作用

Lodewijckx, Inge; Mentens, Nicole; Jacobs, Kris; Cools, Jan

Suz12 inactivation cooperates with JAK3 mutant signaling in the development of T-cell acute lymphoblastic leukemia.

Suz12 失活与 JAK3 突变信号传导协同作用,导致 T 细胞急性淋巴细胞白血病的发生

Broux Michael, Prieto Cristina, Demeyer Sofie, Vanden Bempt Marlies, Alberti-Servera Llucia, Lodewijckx Inge, Vandepoel Roel, Mentens Nicole, Gielen Olga, Jacobs Kris, Geerdens Ellen, Vicente Carmen, de Bock Charles E, Cools Jan

Ruxolitinib Synergizes With Dexamethasone for the Treatment of T-cell Acute Lymphoblastic Leukemia

鲁索替尼与地塞米松联用可协同治疗T细胞急性淋巴细胞白血病

Verbeke, Delphine; Gielen, Olga; Jacobs, Kris; Boeckx, Nancy; De Keersmaecker, Kim; Maertens, Johan; Uyttebroeck, Anne; Segers, Heidi; Cools, Jan

JAK/STAT Pathway Mutations in T-ALL, Including the STAT5B N642H Mutation, are Sensitive to JAK1/JAK3 Inhibitors

T细胞急性淋巴细胞白血病(T-ALL)中的JAK/STAT通路突变,包括STAT5B N642H突变,对JAK1/JAK3抑制剂敏感。

Govaerts, Inge; Jacobs, Kris; Vandepoel, Roel; Cools, Jan

Salmonella Typhi, Paratyphi A, Enteritidis and Typhimurium core proteomes reveal differentially expressed proteins linked to the cell surface and pathogenicity

伤寒沙门氏菌、甲型副伤寒沙门氏菌、肠炎沙门氏菌和鼠伤寒沙门氏菌核心蛋白质组揭示与细胞表面和致病性相关的差异表达蛋白质

Sara Saleh, Sandra Van Puyvelde, An Staes, Evy Timmerman, Barbara Barbé, Jan Jacobs, Kris Gevaert, Stijn Deborggraeve

Anaplastic lymphoma kinase-positive anaplastic large cell lymphoma with the variant RNF213-, ATIC- and TPM3-ALK fusions is characterized by copy number gain of the rearranged ALK gene

伴有RNF213、ATIC和TPM3-ALK融合变异的间变性淋巴瘤激酶阳性间变性大细胞淋巴瘤的特征是重排的ALK基因拷贝数增加。

van der Krogt, Jo-Anne; Bempt, Marlies Vanden; Ferreiro, Julio Finalet; Mentens, Nicole; Jacobs, Kris; Pluys, Ursula; Doms, Kathleen; Geerdens, Ellen; Uyttebroeck, Anne; Pierre, Pascal; Michaux, Lucienne; Devos, Timothy; Vandenberghe, Peter; Tousseyn, Thomas; Cools, Jan; Wlodarska, Iwona