日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The unique role of nucS-mediated noncanonical mismatch repair in Mycobacterium tuberculosis resistance evolution

nucS介导的非经典错配修复在结核分枝杆菌耐药性进化中的独特作用

Martín-Blecua, Isabel; Sastre-Domínguez, Jorge; Valverde, José Ramón; García-Bravo, Pablo; Ruiz-Enamorado, Ángel; Prados-Rosales, Rafael; Das, Lahari; Jacobs, William R Jr; San Millán, Álvaro; Blázquez, Jesús; Gullón, Sonia

P-1339. In vitro activity of ceftazidime-avibactam and comparators against Pseudomonas aeruginosa collected worldwide stratified by age group, ATLAS Global Surveillance Program, 2019-2023

P-1339. 头孢他啶-阿维巴坦及其对照药物对全球范围内按年龄组分层收集的铜绿假单胞菌的体外活性,ATLAS全球监测计划,2019-2023年

Jung, Yookyung; Chen, Bing; Vilchèze, Catherine; Jacobs, William R; Entenberg, David; Negassa, Meti T; Beyene, Erko; Mogus, Lia; Demsis, Wondmagegn; Dhabessa, Jiksa; Hackel, Meredith; Stone, Gregory; Perez, Katherine; Irani, Paurus; Sahm, Daniel F

Loss of the PPE71-esxX-esxY-PPE38 locus drives adaptive transcriptional responses and hypervirulence of Mycobacterium tuberculosis lineage 2

PPE71-esxX-esxY-PPE38基因座的缺失驱动结核分枝杆菌2系的适应性转录反应和高毒力

Koleske, Benjamin; Schill, Courtney; Rajagopalan, Saranathan; Shee, Somnath; Martinez-Martinez, Yazmin B; Gupta, Manish; Shen, Jessica; Jacobs, William R Jr; Bishai, William R

Loss of the ESX-5 secretion locus in Mycobacterium tuberculosis reshapes the mycomembrane and enhances ESX-1 substrate secretion

结核分枝杆菌中ESX-5分泌基因座的缺失会重塑分枝杆菌膜并增强ESX-1底物的分泌。

Koleske, Benjamin; Rajagopalan, Saranathan; Schill, Courtney; Lun, Shichun; Vilchèze, Catherine; Das, Lahari; Gupta, Manish; Martinez-Martinez, Yazmin B; Bishai, William R; Jacobs, William R Jr

Mycobacteriophage-mediated gene transfer enables in vitro drug screening and in vivo tracking of Mycobacterium leprae

利用分枝杆菌噬菌体介导的基因转移,可以进行体外药物筛选和麻风分枝杆菌的体内追踪。

Das, Lahari; Chen, Bing; Rajagopalan, Saranathan; Vilcheze, Catherine; Mulholland, Claire V; Berney, Michael; Andrews, Patrick K; Edwards, Ashley; Lahiri, Ramanuj; Jacobs, William R Jr

Luciferase reporter mycobacteriophage (TM4::GeNL) enables rapid assessment of drug susceptibilities and inducible macrolide resistance in Mycobacterium abscessus complex

荧光素酶报告基因分枝杆菌噬菌体(TM4::GeNL)能够快速评估脓肿分枝杆菌复合群的药物敏感性和诱导型大环内酯类耐药性。

Rajagopalan, Saranathan; Das, Lahari; Kohlerschmidt, Donna J; Rourke, Amy K; Shakir, Salika M; Larsen, Michelle H; O'Donnell, Max R; Szymczak, Wendy A; Escuyer, Vincent E; Thwe, Phyu M; Jacobs, William R Jr

Vitamin C potentiates the killing of Mycobacterium tuberculosis by bedaquiline through metabolic disruption

维生素C通过代谢干扰增强贝达喹啉对结核分枝杆菌的杀灭作用。

Vilchèze, Catherine; Rajagopalan, Saranathan; Kalluru, Raja Sab; Banaei, Niaz; Jacobs, William R Jr

Engineered Mycobacteriophage TM4::GeNL Rapidly Determines Bedaquiline, Pretomanid, Linezolid, Rifampicin, and Clofazimine Sensitivity in Mycobacterium tuberculosis Clinical Isolates

工程化分枝杆菌噬菌体TM4::GeNL可快速测定结核分枝杆菌临床分离株对贝达喹啉、普瑞托马尼、利奈唑胺、利福平和氯法齐明的敏感性

Rajagopalan, Saranathan; Rourke, Amy K; Asare, Emmanuel; Kohlerschmidt, Donna J; Das, Lahari; Ngema, Senamile L; Mulholland, Claire V; Vilchèze, Catherine; Mahalingam, Vaishnavi; Moodley, Sashen; Truebody, Barry; Mackenzie, Jared; Steyn, Adrie J C; Perumal, Rubeshan; Berney, Michael; Larsen, Michelle H; O'Donnell, Max R; Escuyer, Vincent E; Jacobs, William R Jr

The unique role of nucS -mediated non-canonical mismatch repair in Mycobacterium tuberculosis resistance evolution

nucS介导的非经典错配修复在结核分枝杆菌耐药性进化中的独特作用

Martín-Blecua, Isabel; Valverde, José Ramón; García-Bravo, Pablo; Ruiz-Enamorado, Ángel; Prados-Rosales, Rafael; Sastre-Domínguez, Jorge; Das, Lahari; Jacobs, William R; San Millán, Álvaro; Blázquez, Jesús; Gullón, Sonia

An unusual genetic switch controls Mycobacterium avium pathogenesis, antibiotic resistance and colony morphology.

一种不寻常的基因开关控制着鸟分枝杆菌的致病性、抗生素耐药性和菌落形态

Nilsson Hannah J, Netter Zoe, Tuncel Miles, Garelis Nicholas E, Siddiqui Nabila, Semaan Mira, McCall Rita M, Dangerfield Kyla, Cox Ella K, Britt Laura, Voorhies Mark, Roberts Allison W, Mitchell Gabriel, Cangelosi Gerard A, Jacobs William R, Sil Anita, Budzik Jonathan M, Cox Jeffery S