日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

BMP receptor 2 inhibition regulates mitochondrial bioenergetics to induce synergistic cell death with BCL-2 inhibitors in leukemia and NSLC cells

BMP 受体 2 抑制可调节线粒体生物能量学,与 BCL-2 抑制剂一起诱导白血病和 NSLC 细胞发生协同细胞死亡

Ashley Toussaint, Manohar Singh, Guoquiang Wang, Monica Driscoll, Vrushank Bhatt, Jean De La Croix Ndong, Sahil Shuaib, Harrison Zoltowski, John Gilleran, Youyi Peng, Anastassiia Tsymbal, Dongxuan Jia, Jacques Roberge, Hellen Chiou, Jessie Yanxiang Guo, Daniel Herranz, John Langenfeld

Bone morphogenetic protein inhibitors and mitochondria targeting agents synergistically induce apoptosis-inducing factor (AIF) caspase-independent cell death in lung cancer cells

骨形态发生蛋白抑制剂和线粒体靶向剂协同诱导肺癌细胞凋亡诱导因子 (AIF) caspase 非依赖性细胞死亡

Arindam Mondal, Jacques Roberge, John Gilleran, Youyi Peng, Dongxuan Jia, Moumen Akel, Yash Patel, Harrison Zoltowski, Anupama Doraiswamy, John Langenfeld

Bone morphogenetic protein signaling regulation of AMPK and PI3K in lung cancer cells and C. elegans

骨形态发生蛋白信号调控肺癌细胞和秀丽隐杆线虫中的AMPK和PI3K

Mehul Vora, Arindam Mondal, Dongxuan Jia, Pranya Gaddipati, Moumen Akel, John Gilleran, Jacques Roberge, Christopher Rongo, John Langenfeld

Ym155 localizes to the mitochondria leading to mitochondria dysfunction and activation of AMPK that inhibits BMP signaling in lung cancer cells

Ym155 定位到线粒体,导致线粒体功能障碍和 AMPK 激活,从而抑制肺癌细胞中的 BMP 信号传导

Arindam Mondal, Dongxuan Jia, Vrushank Bhatt, Moumen Akel, Jacques Roberge, Jessie Yanxiang Guo, John Langenfeld

Bone morphogenetic protein receptor 2 inhibition destabilizes microtubules promoting the activation of lysosomes and cell death of lung cancer cells

骨形态发生蛋白受体 2 抑制会破坏微管稳定性,从而促进溶酶体的激活和肺癌细胞的细胞死亡

Arindam Mondal, Rachel NeMoyer, Mehul Vora, Logan Napoli, Zoya Syed, Elaine Langenfeld, Dongxuan Jia, Youyi Peng, John Gilleran, Jacques Roberge, Christopher Rongo, Salma K Jabbour, John Langenfeld